Differential ligand binding specificities of recombinant CD11b/CD18 integrin I-domain.

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Integrins: Versatility, modulation, and signaling in cell adhesion

1992 • 9,986 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Integrins.

1991 • 1,369 citations

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells.

1988 • 988 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 962 citations

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

Structure and function of the leukocyte adhesion molecules CD11/CD18

1990 • 785 citations

Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor.

1982 • 615 citations

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

1985 • 593 citations

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1993 • 546 citations

A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen.

1993 • 523 citations

Platelet receptor recognition site on human fibrinogen. Synthesis and structure-function relationship of peptides corresponding to the carboxy-terminal segment of the .gamma. chain

1984 • 479 citations

Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen.

1988 • 457 citations

Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.

1986 • 423 citations

A novel divalent cation-binding site in the a domain of the ?2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1993 • 383 citations

Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen.

1988 • 374 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation.

1986 • 298 citations

The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.

1988 • 281 citations

The saturable high affinity association of factor X to ADP-stimulated monocytes defines a novel function of the Mac-1 receptor.

1988 • 279 citations

The superfamily of proteins with von Willebrand factor type A-like domains: one theme common to components of extracellular matrix, hemostasis, cellular adhesion, and defense mechanisms

1991 • 206 citations

The structural motif glycine 190-valine 202 of the fibrinogen gamma chain interacts with CD11b/CD18 integrin (alpha M beta 2, Mac-1) and promotes leukocyte adhesion.

1993 • 190 citations

Monoclonal antibody-defined functional epitopes on the adhesion- promoting glycoprotein complex (CDw18) of human neutrophils

1986 • 173 citations

A monoclonal antibody reacting with distinct adhesion molecules defines a transition in the functional state of the receptor CD11b/CD18 (Mac-1).

1988 • 166 citations

The cell surface glycoprotein Mac-1 (CD11b/CD18) mediates neutrophil adhesion and modulates degranulation independently of its quantitative cell surface expression.

1989 • 158 citations

Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3).

1988 • 140 citations

A novel LFA-1 activation epitope maps to the I domain.

1993 • 136 citations

Mechanism of inhibition of immunoglobulin G-mediated phagocytosis by monoclonal antibodies that recognize the Mac-1 antigen.

1988 • 125 citations

Expression of native and truncated forms of the human integrin alpha 1 subunit.

1993 • 108 citations

High molecular weight kininogen inhibits fibrinogen binding to cytoadhesins of neutrophils and platelets.

1989 • 89 citations

Fibrinogen association with human monocytes: Evidence for constitutive expression of fibrinogen receptors and for involvement of Mac-1 (CD18, CR3) in the binding

1988 • 60 citations

Structurally Homologous Ligand Binding of Integrin Mac-1 and Viral Glycoprotein C Receptors

1991 • 50 citations

Characterization of the gene for the human high affinity IgE receptor (Fc epsilon RI) alpha-chain.

1993 • 34 citations

Functional studies of truncated soluble intercellular adhesion molecule 1 expressed in Escherichia coli

1993 • 21 citations