Muscimol-Like Discriminative Stimulus Effects of GABA Agonists in Rats

γ‐VINYL GABA (4‐amino‐hex‐5‐enoic acid), A NEW SELECTIVE IRREVERSIBLE INHIBITOR OF GABA‐T: EFFECTS ON BRAIN GABA METABOLISM IN MICE¹

1977 • 472 citations

Mechanism of anticonvulsant action of valproate

1982 • 344 citations

Vigabatrin

1991 • 309 citations

Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.

1986 • 272 citations

Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor

1991 • 233 citations

(R)‐N‐[4,4‐Bis(3‐Methyl‐2‐Thienyl)but‐3‐en‐1‐yl]Nipecotic Acid Binds with High Affinity to the Brain γ‐Aminobutyric Acid Uptake Carrier

1990 • 228 citations

Propofol Activates GABAA Receptor-Chloride Ionophore Complex in Dissociated Hippocampal Pyramidal Neurons of the Rat

1993 • 217 citations

Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons

1990 • 197 citations

Classification of drugs according to their discriminable effects in rats.

1974 • 176 citations

Inhibitors of GABA metabolism

1979 • 170 citations

DT‐n‐PROPYLACETATE AND GABA DEGRADATION. PREFERENTIAL INHIBITION OF SUCCINIC SEMIALDEHYDE DEHYDROGENASE AND INDIRECT INHIBITION OF GABA‐TRANSAMINASE

1979 • 147 citations

Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits.

1995 • 133 citations

The pharmacology of GABA-transaminase inhibitors

1981 • 116 citations

Discriminative stimulus properties of benzodiazepines, barbiturates and pharmacologically related drugs; Relation to some intrinsic and anticonvulsant effects

1976 • 115 citations

Transduction Mechanisms of Drug Stimuli

1988 • 113 citations

GABAA Receptor Agonists, Partial Agonists, and Antagonists. Design and Therapeutic Prospects

1994 • 102 citations

Ethanol drug discrimination in rats: substitution with GABA agonists and NMDA antagonists.

1994 • 93 citations

gamma-Aminobutyric acid (GABA) receptor stimulation. II. Specificity of progabide (SL 76002) and SL 75102 for the GABA receptor.

1982 • 81 citations

Evidence that gaba mechanisms mediate the anxiolytic action of benzodiazepines: A study with valproic acid

1980 • 78 citations

Lorazepam and pentobarbital drug discrimination in baboons: cross-drug generalization and interaction with Ro 15-1788.

1983 • 73 citations

Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.

1985 • 68 citations

Discriminative stimulus effects of atypical anxiolytics in baboons and rats.

1986 • 68 citations

Anesthetics Affect the Uptake but Not the Depolarization-evoked Release of GABA in Rat Striatal Synaptosomes

1995 • 64 citations

Differential generalization to pentobarbital in rats trained to discriminate lorazepam, chlordiazepoxide, diazepam, or triazolam

1989 • 58 citations

Gamma-vinyl GABA

1985 • 52 citations

Discriminative stimulus effects of pentobarbital in pigeons

1980 • 41 citations

Pentobarbital-like discriminative stimulus effects of direct GABA agonists in rats

1993 • 26 citations

Tiagabine: A Novel Drug with a GABAergic Mechanism of Action

1994 • 20 citations

Differential modification of pentobarbital stimulus control by d-amphetamine and ethanol

1986 • 20 citations

Tolerance to the discriminative stimulus effects of ethanol

1990 • 19 citations

Discriminative Stimulus Properties of Anxiolytic and Sedative Drugs: Pharmacological Specificity

1988 • 18 citations

Midazolam cue in rats: effects of drugs acting on GABA and 5-hydroxytryptamine systems, anticonvulsants and sedatives

1987 • 18 citations

The discriminative stimulus effects of muscimol in rats.

1997 • 15 citations

Effects of propofol, pentobarbital and alphaxalone on binding in rat cerebral cortex

1994 • 14 citations

Temperature and anion dependence of allosteric interactions at the γ-aminobutyric acid-benzodiazepine receptor

1992 • 14 citations

Progabide: a new GABA-mimetic agent in clinical use.

1985 • 14 citations

Discriminative stimulus effects of presynaptic GABA agonists in pentobarbital-trained rats

1994 • 9 citations

The anticonvulsant effects of propofol, diazepam, and thiopental, against picrotoxin-induced seizure in the rat.

1993 • 8 citations

GABAmimetic drugs in hyperkinetic involuntary movement disorders and their effects on mental status

1990 • 5 citations