The genetic basis of autoantibody production

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

2004 • 1,392 citations

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

2003 • 1,143 citations

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

2002 • 756 citations

Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE

2004 • 665 citations

The Codon 620 Tryptophan Allele of the Lymphoid Tyrosine Phosphatase (LYP) Gene Is a Major Determinant of Graves’ Disease

2004 • 464 citations

Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis

2004 • 392 citations

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

2005 • 372 citations

The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status

2004 • 203 citations

Association of the TSHR gene with Graves' disease: the first disease specific locus

2005 • 176 citations

Interrelationship of major histocompatibility complex class II alleles and autoantibodies in four ethnic groups with various forms of myositis

1996 • 167 citations

In primary Sjögren's syndrome, HLA class II is associated exclusively with autoantibody production and spreading of the autoimmune response

2003 • 164 citations

Specific amino acid residues in the second hypervariable region of HLA-DQA1 and DQB1 chain genes promote the Ro (SS-A)/La (SS-B) autoantibody responses.

1991 • 158 citations

Genetics in coeliac disease

2005 • 132 citations

The genetic contribution to the pathogenesis of rheumatoid arthritis

1998 • 128 citations

The emerging role of the CTLA-4 gene in autoimmune endocrinopathies

2004 • 124 citations

Associations with autoimmune disorders and HLA class I and II antigens in inclusion body myositis

2004 • 118 citations

Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant.

1991 • 118 citations

Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: Ethnogeographic influences in the genetics and clinical expression of myositis

2002 • 102 citations

Fcγ receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups

2000 • 97 citations

Comparison of HLA class II genes in Caucasoid, Chinese, and Japanese patients with primary Sjögren's syndrome.

1993 • 89 citations

Association of a functional CD19 polymorphism with susceptibility to systemic sclerosis

2004 • 83 citations

HLA-DPB1 alleles association of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with systemic lupus erythematosus

2003 • 81 citations

The TNF‐863A allele strongly associates with anticentromere antibody positivity in scleroderma

2004 • 67 citations

Polymorphisms of theRo52 gene associated with anti-Ro 52-kd autoantibodies in patients with primary Sj�gren's syndrome

2001 • 66 citations

Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients

2004 • 66 citations

The etiology of autoimmune diabetes and thyroiditis: evidence for common genetic susceptibility

2003 • 65 citations

HLA class II alleles associations of anticardiolipin and anti b2GPI antibodies in a large series of European patients with systemic lupus erythematosus

2000 • 64 citations

Association of transforming growth factor β1 and tumor necrosis factor α polymorphisms with anti‐SSB/La antibody secretion in patients with primary Sjögren's syndrome

2004 • 61 citations

Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis

2004 • 60 citations

Significance of valine/leucine²⁴⁷ polymorphism of β₂‐glycoprotein I in antiphospholipid syndrome: Increased reactivity of anti–β₂‐glycoprotein I autoantibodies to the valine²⁴⁷ β₂‐glycoprotein I variant

2005 • 58 citations

Immunogenetic features in 120 Japanese patients with idiopathic inflammatory myopathy.

2004 • 50 citations

Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes

2005 • 44 citations

Interaction between RANKL and HLA–DRB1 genotypes may contribute to younger age at onset of seropositive rheumatoid arthritis in an inception cohort

2004 • 44 citations

Association of the glutathione S-transferase M1 homozygous null genotype with susceptibility to Sj�gren's syndrome in Japanese individuals

1999 • 40 citations

2 Adrenoceptor gene single nucleotide polymorphisms are associated with rheumatoid arthritis in northern Sweden

2004 • 23 citations

Interleukin-10 promoter microsatellite polymorphisms in systemic lupus erythematosus: association with the anti-Sm immune response

2004 • 21 citations

Association of -1087 IL10 and -308 TNFA gene polymorphisms with serological markers of coeliac disease.

2003 • 20 citations

HLA class II alleles associations of anticardiolipin and anti-beta2GPI antibodies in a large series of European patients with SLE

2000 • 18 citations

Genomic absence of the gene encoding T cell receptor V_β7.2 is linked to the presence of autoantibodies in Sjögren's syndrome

2004 • 10 citations

MHC CLASS II AND NON-MHC GENES IN THE PATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS

2004 • 5 citations

Ankylosing spondylitis

2016 • 5 citations

The Pathogenesis of Ankylosing Spondylitis

2006 • 4 citations

Systemic Lupus Erythematosus

2003 • 2 citations