Induction of apoptosis in childhood acute leukemia by chemotherapeutic agents: Failure to detect evidence of apoptosis in vivo

Proposals for the Classification of the Acute Leukaemias F<scp>rench</scp>‐A<scp>merican</scp>‐B<scp>ritish</scp> (FAB) C<scp>o‐operative</scp> G<scp>roup</scp>

1976 • 5,620 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line

1993 • 898 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Apoptosis induced by anticancer drugs

1992 • 861 citations

Apoptosis: a different type of cell death

1992 • 523 citations

IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells.

1986 • 380 citations

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression.

1992 • 366 citations

Perspectives on mammalian cell death

1988 • 334 citations

The biochemistry of cell death by apoptosis

1990 • 326 citations

Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages.

1982 • 326 citations

Bone marrow-derived stromal cells prevent apoptotic cell death in B- lineage acute lymphoblastic leukemia

1992 • 265 citations

Spontaneous programmed death (apoptosis) of B‐chronic lymphocytic leukaemia cells following their culture in vitro

1989 • 260 citations

Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia.

1993 • 258 citations

Apoptosis Biochemical events and relevance to cancer chemotherapy

1992 • 238 citations

In vitro drug sensitivity of cells from children with leukemia using the MTT assay with improved culture conditions

1990 • 232 citations

Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells

1992 • 195 citations

Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells.

1991 • 189 citations

Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells

1992 • 145 citations

Induction of apoptosis in chronic lymphocytic leukemia cells and its prevention by phorbol ester

1992 • 110 citations

Inhibition of both etoposide-induced DNA fragmentation and activation of poly(ADP-ribose) synthesis by zinc ion

1990 • 78 citations

A quantitative assay for fragmented DNA in apoptotic cells

1992 • 64 citations

Glucocorticosteroids induce DNA fragmentation in human lymphoid leukemia cells

1988 • 49 citations

Effect of combination treatment with analogs of luteinizing hormone-releasing hormone (LH-RH) or somatostatin and 5-fluorouracil on pancreatic cancer in hamsters

1991 • 44 citations

Induction of apoptosis in CD4+ prolymphocytic leukemia by deoxyadenosine and 2′-deoxycoformycin

1992 • 27 citations

DNA fragmentation in childhood T-cell acute lymphoblastic leukaemia.

1987 • 8 citations

Pharmacologic Considerations in the Treatment of Acute Lymphoblastic Leukemia

1988 • 5 citations