Induction of apoptosis in chronic lymphocytic leukemia cells and its prevention by phorbol ester

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGS

1989 • 1,799 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

Death and the cell

1986 • 616 citations

Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis.

1990 • 489 citations

The biochemistry of cell death by apoptosis

1990 • 326 citations

Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex.

1989 • 315 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Spontaneous programmed death (apoptosis) of B‐chronic lymphocytic leukaemia cells following their culture in vitro

1989 • 260 citations

Cellular signalling in programmed cell death (apoptosis)

1990 • 255 citations

THE ESTIMATION OF DEOXYRIBONUCLEIC ACID IN THE PRESENCE OF SIALIC ACID: APPLICATION TO ANALYSIS OF HUMAN GASTRIC WASHINGS

1965 • 239 citations

Anti‐immunoglobulins induce death by apoptosis in WEHI‐231 B lymphoma cells

1990 • 239 citations

Mechanism of action of the phorbol ester tumor promoters: Specific receptors for lipophilic ligands

1984 • 209 citations

Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells.

1991 • 189 citations

IL-2 protects T lymphocytes from glucocorticoid-induced DNA fragmentation and cell death.

1989 • 158 citations

Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells

1990 • 119 citations

Synergy between zinc and phorbol ester in translocation of protein kinase C to cytoskeleton

1990 • 92 citations

Calcium‐dependent DNA fragmentation in human synovial cells exposed to cold shock

1990 • 82 citations

Inhibition of both etoposide-induced DNA fragmentation and activation of poly(ADP-ribose) synthesis by zinc ion

1990 • 78 citations

NK cell‐induced cytotoxicity is dependent on a Ca²⁺ increase in the target

1990 • 73 citations

Specific loss of microtubules in HL-60 cells leads to programmed cell death (apoptosis)

1990 • 25 citations

B cell development in chronic lymphocytic leukemia.

1987 • 23 citations

Decreased phorbol ester receptor and protein kinase C in P388 murine leukemic cells resistant to etoposide.

1987 • 23 citations

Loss of receptor activity for mouse erythrocytes precedes tumour promoter-induced maturation of chronic lymphocytic leukaemia cells

1981 • 19 citations

Phorbol ester-induced loss of colchicine ultrasensitivity in chronic lymphocytic leukaemia lymphocytes

1985 • 15 citations

Natural Killer Cells and Cytotoxic T Cells Induce DNA Fragmentation in Both Human and Murine Target Cells in Vitro

1989 • 14 citations

12-O-Tetradecanoylphorbol 13-acetate potentiates the action of cAMP in inducing DNA cleavage in thymocytes

1990 • 8 citations