Overexpression of transforming growth factor β1 in arterial endothelium causes hyperplasia, apoptosis, and cartilaginous metaplasia

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Compensatory Enlargement of Human Atherosclerotic Coronary Arteries

1987 • 3,549 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

Handbook of Experimental Pharmacology

1968 • 789 citations

Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.

1990 • 734 citations

Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme.

1995 • 643 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Significance of quiescent smooth muscle migration in the injured rat carotid artery.

1985 • 570 citations

Production of transforming growth factor beta 1 during repair of arterial injury.

1991 • 539 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

Evidence for apoptosis in human atherogenesis and in a rat vascular injury model.

1995 • 484 citations

TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify.

1994 • 454 citations

Atherosclerosis and Coronary Artery Disease

1996 • 438 citations

Cartilage-derived morphogenetic proteins. New members of the transforming growth factor-beta superfamily predominantly expressed in long bones during human embryonic development.

1994 • 415 citations

Proliferation of Human Smooth Muscle Cells Promoted by Lipoprotein(a)

1993 • 407 citations

Direct transfer of transforming growth factor beta 1 gene into arteries stimulates fibrocellular hyperplasia.

1993 • 387 citations

The serum concentration of active transforming growth factor-β is severely depressed in advanced atherosclerosis

1995 • 386 citations

Expression of transforming growth factor-beta 1 is increased in human vascular restenosis lesions.

1992 • 383 citations

Activation of transforming growth factor-β is inhibited in transgenic apolipoprotein(a) mice

1994 • 363 citations

Significance of quiescent smooth muscle migration in the injured rat carotid artery.

1985 • 342 citations

Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells.

1988 • 305 citations

Antibodies against transforming growth factor-beta 1 suppress intimal hyperplasia in a rat model.

1994 • 303 citations

S-100 protein in human chondrocytes

1982 • 289 citations

Promoter Sequences of the Human Transforming Growth Factor-β1 Gene Responsive to Transforming Growth Factor-β1 Autoinduction

1989 • 254 citations

Transforming growth factor beta 1 promotes the differentiation of endothelial cells into smooth muscle-like cells in vitro

1992 • 247 citations

TGF-β1 Prevents Hypertrophy of Epiphyseal Chondrocytes: Regulation of Gene Expression for Cartilage Matrix Proteins and Metalloproteases

1993 • 240 citations

Site-directed Mutagenesis of Cysteine Residues in the Pro Region of the Transforming Growth Factor β1 Precursor

1989 • 220 citations

In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries.

1993 • 210 citations

Kinetics of cellular proliferation after arterial injury. II. Inhibition of smooth muscle growth by heparin.

1985 • 195 citations

Growth factor expression in aorta of normotensive and hypertensive rats.

1989 • 195 citations

Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis.

1984 • 191 citations

Tamoxifen elevates transforming growth factor–β and suppresses diet–induced formation of lipid lesions in mouse aorta

1995 • 139 citations

In Vivo Effect of TGF-β1

1995 • 124 citations

Endothelium-Specific In Vivo Gene Transfer

1995 • 116 citations

Endothelial cell behavior after denudation injury is modulated by transforming growth factor-beta1 and fibronectin.

1989 • 101 citations

S-100 protein in human cartilage lesions.

1986 • 90 citations

Genetic Determination of Cartilaginous Metaplasia in Mouse Aorta

1995 • 76 citations

Immunohistochemical detection of active transforming growth factor-beta in situ using engineered tissue.

1995 • 66 citations

In Vivo Adenovirus-Mediated Gene Transfer Via the Pulmonary Artery of Rats

1995 • 52 citations

Identification of a cis-Acting Sequence in the Human Plasminogen Activator Inhibitor Type-1 Gene That Mediates Transforming Growth Factor-β1 Responsiveness in Endothelium in Vivo

1996 • 43 citations

Reversal of coronary atherosclerosis. Clinical promise as the basis for noninvasive management of coronary artery disease.

1994 • 43 citations

Cartilaginous Transformation of the Aortic Valve

1973 • 35 citations

Regional Variability in the Time Course of TGF-β1 Expression, Cellular Proliferation and Extracellular Matrix Expansion following Arterial Injury

1997 • 18 citations

Interaction of Therapeutic Diets and Cholesterol-Lowering Drugs in Regression Studies in Animals

1984 • 11 citations

Molecular Identity of Smooth Muscle Cells

1995 • 3 citations