In Vivo Adenovirus-Mediated Gene Transfer Via the Pulmonary Artery of Rats

Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension

1993 • 1,829 citations

The Lung: Scientific Foundations

1991 • 1,181 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

1991 • 983 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis

1994 • 829 citations

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo

1991 • 743 citations

Pathology of the lung

1985 • 702 citations

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis

1993 • 669 citations

The normal human lung: ultrastructure and morphometric estimation of diffusion capacity

1978 • 602 citations

Adenovirus–mediated in vivo gene transfer and expression in normal rat liver

1992 • 451 citations

Inhaled nitric oxide in congenital heart disease.

1993 • 400 citations

Resistance to Parvovirus B19 Infection Due to Lack of Virus Receptor (Erythrocyte P Antigen)

1994 • 348 citations

Adenovirus mediated expression of therapeutic plasma levels of human factor IX in mice

1993 • 345 citations

Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation.

1991 • 340 citations

Adenovirus-Mediated Transfer of the CFTR Gene to Lung of Nonhuman Primates: Toxicity Study

1993 • 324 citations

Efficient catheter-mediated gene transfer into the heart using replication-defective adenovirus.

1994 • 285 citations

Role of early region 3 (E3) in pathogenesis of adenovirus disease.

1989 • 285 citations

The Influence of Hydrogen Ion Concentration and Hypoxia on the Pulmonary Circulation*

1964 • 263 citations

In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.

1993 • 256 citations

New findings in pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

1976 • 251 citations

Elevated immunoreactive endothelin-1 levels in newborn infants with persistent pulmonary hypertension

1993 • 220 citations

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

1992 • 216 citations

In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries.

1993 • 210 citations

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.

1993 • 199 citations

Normobaric hypoxia stimulates endothelin-1 gene expression in the rat

1992 • 182 citations

Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus)

1993 • 173 citations

Anatomic barriers influence the distribution of in vivo gene transfer into the arterial wall. Modeling with microscopic tracer particles and verification with a recombinant adenoviral vector.

1994 • 154 citations

Increased lung endothelin-1 production in rats with idiopathic pulmonary hypertension

1992 • 151 citations

Expression of Escherichia coli β-Galactosidase and Rat HPRT in the CNS of Macaca mulatta Following Adenoviral Mediated Gene Transfer

1994 • 144 citations

A New Animal Model for Human Respiratory Tract Disease Due to Adenovirus

1984 • 128 citations

Increased Pulmonary Artery Elastolytic Activity in Adult Rats with Monocrotaline-induced Progressive Hypertensive Pulmonary Vascular Disease Compared with Infant Rats with Nonprogressive Disease

1992 • 125 citations

Chronic hypoxic pulmonary hypertension in rats and increased elastolytic activity

1991 • 122 citations

Ultrastructural findings in lung biopsy material from children with congenital heart defects.

1980 • 101 citations

Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension

1993 • 92 citations

Histamine H1- and H2-receptors in pulmonary and systemic vasculature of the dog

1975 • 92 citations

Protection of rabbit lungs from endotoxin injury by in vivo hyperexpression of the prostaglandin G/H synthase gene.

1994 • 90 citations

Isolated single-lung perfusion with doxorubicin is pharmacokinetically superior to intravenous injection

1993 • 80 citations

Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension.

1990 • 77 citations

Profile of paediatric patients with pulmonary hypertension judged by responsiveness to vasodilators.

1993 • 77 citations

Lymphatics and Lymphoid Tissues

1967 • 59 citations

Adenoviral Vector-Mediated Gene Transfer into Sheep Arteries Using a Double-Balloon Catheter

1994 • 49 citations

In vivo adenovirus-mediated gene transfer to lungs via pulmonary artery

1994 • 49 citations

Catheterization of the pulmonary artery in the closed-chest rat

1981 • 44 citations

Advances in the Treatment of Persistent Pulmonary Hypertension of the Newborn

1993 • 42 citations

Insulin-like Growth Factor I and Pulmonary Hypertension Induced by Continuous Air Embolization in Sheep

1992 • 42 citations

Transforming growth factor-beta 1 is decreased in remodeling hypertensive bovine pulmonary arteries.

1992 • 32 citations

Normal Anatomy and Histology

2001 • 29 citations

Pulmonary Vascular Obstructive Disease

1993 • 21 citations