Genetic Determination of Cartilaginous Metaplasia in Mouse Aorta

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1992 • 2,216 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

1994 • 1,646 citations

Bone morphogenetic protein expression in human atherosclerotic lesions.

1993 • 1,014 citations

Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op/op) mouse.

1990 • 1,012 citations

Absence of Thymus in a Mouse Mutant

1968 • 701 citations

Depletion of CD4 ⁺ T Cells in Major Histocompatibility Complex Class II-Deficient Mice

1991 • 673 citations

Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression.

1994 • 632 citations

High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.

1994 • 616 citations

RECOMBINANT-INBRED STRAINS AN AID TO FINDING IDENTITY, LINKAGE, AND FUNCTION OF HISTOCOMPATIBILITY AND OTHER GENES

1971 • 595 citations

TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify.

1994 • 454 citations

Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis.

1994 • 357 citations

RECOMBINANT INBRED STRAINS: USE IN GENE MAPPING

1978 • 351 citations

Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques.

1994 • 314 citations

Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: A quantitative pathologic comparison study

1992 • 313 citations

Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease.

1992 • 278 citations

The diagnostic and prognostic significance of coronary artery calcification. A report of 800 cases.

1980 • 275 citations

Origins of Inbred Mice

1978 • 263 citations

Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques. A possible association with calcification.

1993 • 259 citations

Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification.

1994 • 244 citations

Aortic calcified plaques and cardiovascular disease (the Framingham study)

1990 • 236 citations

Coronary Calcification

1965 • 221 citations

Incidence and significance of coronary artery calcification.

1974 • 178 citations

Calcification of the coronary arteries.

1959 • 164 citations

Calcification in porcine xenograft valves in children

1980 • 151 citations

Pathologic findings after cardiac valve replacement with glutaraldehyde-fixed porcine valves

1977 • 142 citations

CALCIFICATION IN THE CORONARY ARTERIES AND ITS RELATIONSHIP TO ARTERIOSCLEROSIS AND MYOCARDIAL INFARCTION.

1964 • 140 citations

Animal models in atherosclerosis research

1985 • 136 citations

Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.

1993 • 130 citations

Mechanism of calcification in atherosclerosis

1994 • 117 citations

Mechanism of calcification of porcine bioprosthetic aortic valve cusps: Role of T-lymphocytes

1983 • 76 citations

Coronary Artery Calcification: Its Relationship to Coronary Artery Stenosis and Myocardial Infarction

1968 • 73 citations

c-fos expression precedes osteogenic differentiation of cartilage cells in vitro.

1990 • 71 citations

Immune-complex-mediated vasculitis increases coronary artery lipid accumulation in autoimmune-prone MRL mice.

1993 • 69 citations

Differential accumulation of intimal monocyte-macrophages relative to lipoproteins and lipofuscin corresponds to hemodynamic forces on cardiac valves in mice.

1991 • 50 citations

Observations on the mechanically induced differentiation of cartilage from fibrous connective tissue

1970 • 45 citations

Cartilaginous Transformation of the Aortic Valve

1973 • 35 citations

Calcific deposits developing in a bovine pericardial bioprosthetic valve 3 days after implantation.

1981 • 34 citations

Constitutive myc expression impairs hypertrophy and calcification in cartilage

1992 • 27 citations

Cartilaginous focus at the base of the non-coronary semilunar valve of the aorta in rats of different ages☆

1968 • 23 citations

Involvement of the tyrosinase gene in the deposition of cardiac lipofuscin in mice. Association with aortic fatty streak development.

1993 • 21 citations

Cartilaginous Metaplasia in Calcific Aortic Valve Disease

1990 • 20 citations

Aortic cartilage produced by intramural carrageenan.

1963 • 17 citations

Matrix vesicle calcification of rat aorta in millipore chambers

1978 • 12 citations

Deleted Work

1955 • 0 citations