Heat-shock protein hsp90 governs the activity of pp60v-src kinase.

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures.

1989 • 624 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Steroid receptors and their associated proteins.

1993 • 513 citations

The effects of reciprocal changes in temperature on the transformed state of cells infected with a Rous sarcoma virus mutant

1971 • 411 citations

Chapter 16 The Use of Fluorescent DNA-Binding Agent for Detecting and Separating Yeast Mitochondrial DNA

1975 • 364 citations

The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins

1981 • 360 citations

DNA sequences homologous to vertebrate oncogenes are conserved in Drosophila melanogaster.

1981 • 269 citations

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70.

1993 • 266 citations

A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein.

1981 • 246 citations

hsp82 Is an Essential Protein That Is Required in Higher Concentrations for Growth of Cells at Higher Temperatures

1989 • 244 citations

Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts.

1984 • 239 citations

Interaction of the Rous Sarcoma Virus Protein pp60 src with the Cellular Proteins pp50 and pp90

1986 • 223 citations

The nucleotide sequence and the tissue-specific expression of Drosophila c-src

1985 • 201 citations

Genetics of src: Structure and Functional Organization of a Protein Tyrosine Kinase

1989 • 197 citations

Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex.

1990 • 190 citations

A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity.

1985 • 126 citations

Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region

1987 • 117 citations

Reconstitution of the multiprotein complex of pp60src, hsp90, and p50 in a cell-free system.

1992 • 93 citations

Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: Evidence for a common ancestor to the src and abl cellular genes

1983 • 91 citations

Characterization of avian and viral p60src proteins expressed in yeast.

1987 • 84 citations

Interaction of the glucocorticoid receptor with the Mr 90,000 heat shock protein: an evolving model of ligand-mediated receptor transformation and translocation.

1989 • 74 citations

Protein-Tyrosine Kinase Activity in Saccharomyces cerevisiae

1986 • 67 citations

Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells.

1987 • 67 citations

Drosophila abl and genetic redundancy in signal transduction

1991 • 63 citations

The transforming proteins of PRCII virus and Rous sarcoma virus form a complex with the same two cellular phosphoproteins

1982 • 49 citations

Identification of a 60-Kilodalton Stress-Related Protein, p60, which Interacts with hsp90 and hsp70

1993 • 48 citations

A Mutation at the ATP-Binding Site of pp60^v-src Abolishes Kinase Activity, Transformation, and Tumorigenicity

1985 • 39 citations

Expression of Rous Sarcoma Virus Transforming Protein pp60^v-src in Saccharomyces cerevisiae Cells

1987 • 26 citations