Selective attenuation of μ-opioid receptor-mediated effects in rat sensory neurons by intrathecal administration of antisense oligodeoxynucleotides

Studies on the direct spinal action of narcotics in the production of analgesia in the rat.

1977 • 543 citations

Activation of μ opioid receptors inhibits transient high- and low-threshold Ca 2+ currents, but spares a sustained current

1991 • 202 citations

Selective loss of δ opioid analgesia and binding by antisense oligodeoxynucleotides to a δ opioid receptor

1994 • 192 citations

Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitro

1996 • 188 citations

Involvement of the mu-opiate receptor in peripheral analgesia

1989 • 172 citations

Direct cutaneous hyperalgesia induced by adenosine

1990 • 143 citations

C-fos antisense oligodeoxynucleotide increases formalin-induced nociception and regulates preprodynorphin expression

1995 • 113 citations

Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor

1994 • 110 citations

Opioid and adenosine peripheral antinociception are subject to tolerance and withdrawal

1995 • 104 citations

Kappa- and delta-opioids block sympathetically dependent hyperalgesia

1991 • 74 citations

Mu-opioid agonist enhancement of prostaglandin-induced hyperalgesia in the rat: A G-protein βγ subunit-mediated effect?

1995 • 61 citations

Comparison of intradermal and subcutaneous hyperalgesic effects of inflammatory mediators in the rat

1993 • 40 citations

ANTISENSE OLIGONUCLEOTIDES: A NEW TOOL IN NEUROSCIENCE

1994 • 37 citations

Stimulation of spinal δ-opioid receptors in mice selectively enhances the attenuation of δ-opioid receptor-mediated antinociception by antisense oligodeoxynucleotide

1995 • 15 citations