DNA repair in genes

A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

1973 • 4,217 citations

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

1963 • 2,742 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 • 848 citations

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

1985 • 829 citations

DNA repair: a laboratory manual of research procedures

1981 • 818 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations

1983 • 719 citations

PROTEIN-NUCLEIC ACID INTERACTIONS IN TRANSCRIPTION: A Molecular Analysis

1984 • 620 citations

A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region

1983 • 618 citations

Viral oncogenes

1985 • 605 citations

Repair deficient human disorders and cancer

1978 • 491 citations

Preferential DNA repair of an active gene in human cells.

1986 • 455 citations

Failure of RNA synthesis to recover after UV irradiation; An early defect in cells from individuals with Cockayne syndrome and xeroderma pigmentosum

1982 • 418 citations

Chromatin assembly in Xenopus oocytes: In vivo studies

1984 • 404 citations

Transcriptionally active chromatin

1984 • 361 citations

Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus

1980 • 336 citations

Cellular responses to DNA damage

1983 • 301 citations

ATP-dependent DNA topoisomerase from D. melanogaster reversibly catenates duplex DNA rings

1980 • 292 citations

Gene amplification, drug resistance, and cancer.

1984 • 284 citations

Modern Biological Theories of Aging

1987 • 274 citations

Heterogeneous DNA damage and repair in the mammalian genome.

1987 • 274 citations

The mouse c-abl locus: Molecular cloning and characterization

1984 • 223 citations

A structural analysis of the role of the nuclear matrix and DNA loops in the organization of the nucleus and chromosome

1984 • 220 citations

Nucleosome rearrangement in human chromatin during UV-induced DNA- reapir synthesis.

1978 • 204 citations

Differential DNA repair in transcriptionally active and inactive proto-oncogenes: c-abl and c-mos

1986 • 202 citations

Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene.

1986 • 196 citations

DNA repair and its inhibition

1984 • 174 citations

Genetic diversity of UV-sensitive DNA repair mutants of Chinese hamster ovary cells.

1981 • 173 citations

Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene.

1986 • 157 citations

Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide

1984 • 154 citations

Torsional stress promotes the DNAase I sensitivity of active genes

1984 • 145 citations

Preferential DNA Repair in Human Cells

1974 • 144 citations

Cancer-prone hereditary diseases with DNA processing abnormalities

1986 • 143 citations

Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.

1983 • 124 citations

Sensitive determination of pyrimidine dimers in DNA of UV-irradiated mammalian cells Introduction of T4 endonuclease V into frozen and thawed cells

1981 • 124 citations

The association of transcribed genes with the nuclear matrix ofDrosophilacells during heat shock

1985 • 114 citations

Dependence of mammalian DNA replication on DNA supercoiling II. Effects of novobiocin on DNA synthesis in Chinese hamster ovary cells

1979 • 114 citations

Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells

1979 • 112 citations

Characterization of a DNA repair domain containing the dihydrofolate reductase gene in Chinese hamster ovary cells.

1986 • 105 citations

Deficient repair of chemical adducts in α DNA of monkey cells

1982 • 101 citations

Dependence of mammalian DNA synthesis on DNA supercoiling. III Characterization of the inhibition of replicative and repair-type DNA synthesis by novobiocin and nalidixic acid

1981 • 96 citations

Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases

1985 • 90 citations

Nonrandom nature of in vivo methylation of dimethylnitrosamine and the subsequent removal of methylated products from rat liver chromatin DNA.

1976 • 89 citations

Processive action of T4 endonuclease V on ultraviolet-irradiated DNA

1980 • 85 citations

Novobiocin inhibition of simian virus 40 DNA replication

1980 • 85 citations

Deoxyribonucleic acid excision repair in chromatin after ultraviolet irradiation of human fibroblasts in culture

1979 • 81 citations

Preferential repair of nuclear matrix associated DNA in xeroderma pigmentosum complementation group C

1984 • 77 citations

Measurement of repair replication by equilibrium sedimentation

1981 • 75 citations

Coordinate amplification of metallothionein I and II genes in cadmium-resistant Chinese hamster cells: implications for mechanisms regulating metallothionein gene expression.

1985 • 71 citations

Novobiocin blocks the Drosophila heat shock response

1985 • 70 citations

Processivity of T4 endonuclease V is sensitive to sodium chloride concentration

1986 • 69 citations

Cellular Moloney Murine Sarcoma (c-mos) Sequences Are Hypermethylated and Transcriptionally Silent in Normal and Transformed Rodent Cells

1982 • 66 citations

Phage T4 endonuclease V stimulates DNA repair replication in isolated nuclei from ultraviolet-irradiated human cells, including xeroderma pigmentosum fibroblasts

1978 • 66 citations

DNA repair in the metallothionein gene increases with transcriptional activation

1987 • 65 citations

Non-random binding of a chemical carcinogen to the DNA in chromatin

1977 • 63 citations

Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity.

1979 • 58 citations

Transient conformation changes in chromatin during excision repair of ultraviolet damage to DNA

1981 • 56 citations

Quantitation of aflatoxin B1 adduction within the ribosomal RNA gene sequences of rat liver DNA.

1984 • 55 citations

Pyrimidine dimers block simian virus 40 replication forks.

1986 • 53 citations

Accessibility of deoxyribonucleic acid in chromatin to the covalent binding of the chemical carcinogen benzo[a]pyrene

1979 • 52 citations

Benzpyrene groups bind preferentially to the DNA of active chromatin in human lung cells

1982 • 51 citations

Specificity and completeness of inhibition of DNA repair by novobiocin and aphidicolin

1982 • 49 citations

Rearrangement of mammalian chromatin structure following excision repair

1982 • 49 citations

IN VIVO EXCISION OF PYRIMIDINE DIMERS IS MEDIATED BY A DNA N‐GLYCOSYLASE IN MICROCOCCUS LUTEUS BUT NOT IN HUMAN FIBROBLASTS

1982 • 49 citations

Distribution of DNA damage in chromatin and its relation to repair in human cells treated with 7-bromomethylbenz(a) anthracene

1979 • 47 citations

Carcinogen aflatoxin B1 is located preferentially in internucleosomal deoxyribonucleic acid following exposure in vivo in rainbow trout

1980 • 42 citations

Cellular Moloney murine sarcoma (c-mos) sequences are hypermethylated and transcriptionally silent in normal and transformed rodent cells.

1982 • 38 citations

Nalidixic Acid, Oxolinic Acid, and Novobiocin Inhibit Yeast Glycyl- and Leucyl-Transfer RNA Synthetases

1981 • 36 citations

Chromatin structure of the human dihydrofolate reductase gene promoter. Multiple protein-binding sites.

1986 • 32 citations

Gene control: Eukaryotic topoisomerases come into the limelight

1985 • 29 citations

Enhanced repair of pyrimidine dimers in coding and non-coding genomic sequences in CHO cells expressing a prokaryotic DNA repair gene

1987 • 28 citations

Intragenomal Distribution of DNA Repair Synthesis: Repair in Satellite and Mainband DNA in Cultured Mouse Cells

1974 • 28 citations

Environmental carcinogenesis

1986 • 27 citations

Methylation of chromosomal DNA by two alkylating agents differing in carcinogenic potential

1981 • 20 citations

Coordinate Expression of Amplified Metallothionein I and II Genes in Cadmium-Resistant Chinese Hamster Cells

1985 • 19 citations

Dermatology in General Medicine

1971 • 18 citations

Effects of Ultraviolet Irradiation and Postirradiation Incubation on Heterogeneous Nuclear RNA Size in Murine Cells

1978 • 15 citations

Comparative effects of growth inhibitors on DNA replication, DNA repair, and protein synthesis in human epidermal keratinocytes.

1986 • 14 citations

Non-random interaction of N-2-acetylaminofluorene and its N-hydroxy metabolite with DNA of rat hepatic parenchymal and non-parenchymal cell nuclei following in vivo administration of carcinogen

1984 • 12 citations

Novobiocin does not inhibit DNA repair in an activve gene

1986 • 11 citations

Coordinate expression of amplified metallothionein I and II genes in cadmium-resistant Chinese hamster cells.

1985 • 11 citations

Factors that affect the initiation of excision-repair in chromatin.

1984 • 10 citations

DNA excision repair in mammalian cells

1980 • 8 citations