Memantine and HIV-associated cognitive impairment: a neuropsychological and proton magnetic resonance spectroscopy study

A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or Less

1997 • 2,670 citations

Memantine in Moderate-to-Severe Alzheimer's Disease

2003 • 1,889 citations

Memantine Treatment in Patients With Moderate to Severe Alzheimer Disease Already Receiving Donepezil

2004 • 1,350 citations

¹H NMR chemical shift selective (CHESS) imaging

1985 • 1,016 citations

Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

2006 • 847 citations

The HNRC 500-Neuropsychology of Hiv infection at different disease stages

1995 • 639 citations

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

1992 • 626 citations

HIV-associated cognitive impairment before and after the advent of combination therapy

2002 • 585 citations

Memantine in severe dementia: results of the9M-best study (benefit and efficacy in severly demented patients during treatment with memantine)

1999 • 532 citations

Changing incidence of AIDS-defining illnesses in the era of antiretroviral combination therapy

1997 • 423 citations

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

1999 • 422 citations

The Epidemiology of Human Immunodeficiency Virus-Associated Neurological Disease in the Era of Highly Active Antiretroviral Therapy

2002 • 406 citations

Human Immunodeficiency Virus-Associated Dementia: An Evolving Disease

2003 • 377 citations

Neuropsychological performance in HIV‐1‐infected homosexual men

1990 • 328 citations

Zidovudine treatment of the AIDS dementia complex: Results of a placebo‐controlled trial

1993 • 275 citations

Synergistic neurotoxicity by human immunodeficiency virus proteins Tat and gp120: Protection by memantine

2000 • 259 citations

Automated single‐voxel proton MRS: Technical development and multisite verification

1994 • 245 citations

Cerebral metabolite abnormalities correlate with clinical severity of HIV-1 cognitive motor complex

1999 • 238 citations

Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia

1999 • 231 citations

HIV-Related Neuropathology, 1985 to 1999: Rising Prevalence of HIV Encephalopathy in the Era of Highly Active Antiretroviral Therapy

2002 • 224 citations

Neuropsychological characterization of the AIDS dementia complex

1988 • 214 citations

Reduced brain N ‐acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus‐seropositive individuals

1993 • 197 citations

Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation

1998 • 194 citations

Highly active antiretroviral treatment in HIV infection

1998 • 190 citations

Computerized and conventional neuropsychological assessment of HIV‐1‐infected homosexual men

1991 • 189 citations

A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age

2004 • 186 citations

Elevated subcortical choline metabolites in cognitively and clinically asymptomatic HIV patients

1999 • 167 citations

Memantine prevents HIV coat protein‐induced neuronal injury in vitro

1992 • 153 citations

Variable benefit in neuropsychological function in HIV-infected HAART-treated patients

2006 • 151 citations

AIDS dementia complex: evaluation with proton MR spectroscopic imaging.

1995 • 147 citations

Highly Active Antiretroviral Therapy Improves Neurocognitive Functioning

2004 • 146 citations

Brain choline-containing compounds are elevated in HIV-positive patients before the onset of AIDS dementia complex

1996 • 143 citations

Neurological outcomes in late HIV infection: adverse impact of neurological impairment on survival and protective effect of antiviral therapy

1999 • 142 citations

Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine

1996 • 139 citations

Efficacy of memantine, an NMDA receptor antagonist, in the treatment of Parkinson's disease

1992 • 137 citations

Normative Data for a Brief Neuropsychological Screening Battery

1991 • 124 citations

Biochemical changes in the frontal lobe of HIV-infected individuals detected by magnetic resonance spectroscopy

1997 • 120 citations

A phase I/II trial of nimodipine for HIV-related neurologic complications

1998 • 111 citations

Correlates of independent HIV-1 replication in the CNS and of its control by antiretrovirals

2002 • 89 citations

Regional patterns of brain metabolites in AIDS dementia complex

2004 • 87 citations

A multi‐center ¹H MRS study of the AIDS dementia complex: Validation and preliminary analysis

2003 • 81 citations

Brain Proton Magnetic Resonance Spectroscopy in HIV-Related Encephalopathy: Identification of Evolving Metabolic Patterns in Relation to Dementia and Therapy

1997 • 81 citations

Memantine Protects Hippocampal Neuronal Function in Murine Human Immunodeficiency Virus Type 1 Encephalitis

2004 • 72 citations

N-acetylaspartate reductions measured by 1H MRSI in cognitively impaired HIV-seropositive individuals

1994 • 67 citations

Memantine in the treatment of senile dementia of the Alzheimer type

1986 • 67 citations

Evaluation of the AIDS dementia complex in clinical trials.

1990 • 66 citations

Localized cerebral proton MR spectroscopy in HIV infection and AIDS.

1994 • 63 citations

Proton Spectroscopy in Asymptomatic HIV-Infected Adults: Initial Results in a Prospective Cohort Study

1996 • 42 citations

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