Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine

Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders

1994 • 2,668 citations

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1994 • 1,342 citations

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

1993 • 800 citations

Central nervous system damage produced by expression of the HIV-1 coat protein gpl20 in transgenic mice

1994 • 678 citations

Secretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1

1990 • 628 citations

Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity

1992 • 626 citations

Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease.

1992 • 531 citations

GFAP promoter directs astrocyte-specific expression in transgenic mice

1994 • 471 citations

Neocortical damage during HIV infection

1991 • 456 citations

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1993 • 447 citations

Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity

1991 • 397 citations

Spectrum of human immunodeficiency virus–associated neocortical damage

1992 • 369 citations

Human immunodeficiency virus type 1 infection of the nervous system: Pathogenetic mechanisms

1993 • 367 citations

Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.

1993 • 348 citations

Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin

1994 • 317 citations

The neuropathogenesis of HIV-1 infection

1994 • 277 citations

Pathology of HIV-1 Infection of the Central Nervous System. A review

1992 • 244 citations

The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.

1993 • 230 citations

Astrocytes in infectious and immune‐mediated diseases of the central nervous system

1993 • 217 citations

Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat

1991 • 207 citations

gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine

1992 • 174 citations

A Review of Neuronal Damage in Human Immunodeficiency Virus Infection

1993 • 169 citations

Neuroprotective effect of memantine demonstrated in vivo and in vitro

1990 • 157 citations

Memantine prevents HIV coat protein‐induced neuronal injury in vitro

1992 • 153 citations

Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120

1992 • 149 citations

Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex.

1994 • 148 citations

HIV envelope protein-induced neuronal damage and retardation of behavioral development in rat neonates

1993 • 132 citations

gp120 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages

1994 • 117 citations

Developmental Expression of the Glial Fibrillary Acidic Protein mRNA in the Central Nervous System and in Cultured Astrocytes

1989 • 107 citations

Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein.

1995 • 92 citations

HIV-related neuronal injury

1994 • 89 citations

HIV, AIDS, And the Brain

1994 • 88 citations

Memantine prevents quinolinic acid-induced hippocampal damage

1992 • 55 citations

Expression of human immunodeficiency virus type 1 in the nervous system of transgenic mice leads to neurological disease

1994 • 49 citations

Transgenic Models to Assess the Neuropathogenic Potential of HIV-1 Proteins and Cytokines

1995 • 31 citations

HIV‐1 Envelope Protein gp120 Potentiates NMDA‐evoked Noradrenaline Release by a Direct Action at Rat Hippocampal and Cortical Noradrenergic Nerve Endings

1994 • 24 citations

Age- and dose-related NMDA induction of Fos-like immunoreactivity and c-fos mRNA in the arcuate nucleus of immature female rats

1993 • 22 citations

Development of dopamine and systems in rat brain: the effect of prenatal phencyclidine exposure

1993 • 17 citations

Cerebral pathology in AIDS: a new nomenclature and pathogenetic concepts.

1992 • 13 citations