Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia

Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

1998 • 9,382 citations

The clinical evaluation of chemotherapeutic agents in cancer

1949 • 2,793 citations

Decay characteristics of HIV-1-infected compartments during combination therapy

1997 • 1,849 citations

The AIDS dementia complex: I. Clinical features

1986 • 1,679 citations

Spatial Localization in NMR Spectroscopy in Vivo

1987 • 1,342 citations

Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types

1993 • 997 citations

Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus‐type 1 (HIV‐1) infection

1991 • 755 citations

Dementia in AIDS patients

1993 • 671 citations

Impact of new antiretroviral combination therapies in HIV infected patients in Switzerland: prospective multicentre study

1997 • 630 citations

Secretion of Neurotoxins by Mononuclear Phagocytes Infected with HIV-1

1990 • 628 citations

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide

1988 • 616 citations

Evidence for Early Central Nervous System Involvement in the Acquired Immunodeficiency Syndrome (AIDS) and Other Human Immunodeficiency Virus (HIV) Infections

1987 • 573 citations

Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease

1998 • 553 citations

HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

1997 • 527 citations

Absolute Quantitation of Water and Metabolites in the Human Brain. II. Metabolite Concentrations

1993 • 499 citations

Dementia Associated with the Acquired Immunodeficiency Syndrome

1995 • 465 citations

Neocortical damage during HIV infection

1991 • 456 citations

Relationship between human immunodeficiency virus—associated dementia and viral load in cerebrospinal fluid and brain

1997 • 397 citations

In vivo 1H MRS choline: Correlation with in vitro chemistry/histology

1996 • 367 citations

Cerebral white matter changes in acquired immunodeficiency syndrome dementia: Alterations of the blood‐brain barrier

1993 • 333 citations

Neuropsychological performance in HIV‐1‐infected homosexual men

1990 • 328 citations

Reduced basal ganglia volume in HIV‐1‐associated dementia

1993 • 318 citations

Low prevalence of neurological and neuropsychological abnormalities in otherwise healthy HIV‐1–infected individuals: Results from the multicenter AIDS cohort study

1989 • 267 citations

Cerebral metabolite abnormalities correlate with clinical severity of HIV-1 cognitive motor complex

1999 • 238 citations

The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir

1998 • 235 citations

Reduced brain N ‐acetylaspartate suggests neuronal loss in cognitively impaired human immunodeficiency virus‐seropositive individuals

1993 • 197 citations

Proton spectroscopy of the brain in HIV infection: correlation with clinical, immunologic, and MR imaging findings.

1993 • 157 citations

Brain choline-containing compounds are elevated in HIV-positive patients before the onset of AIDS dementia complex

1996 • 143 citations

Clinical confirmation of the American Academy of Neurology algorithm for HIV-1-associated cognitive/motor disorder

1996 • 132 citations

HIV-related metabolic abnormalities in the brain: depiction with proton MR spectroscopy with short echo times.

1996 • 131 citations

Abnormal cerebral glucose metabolism in HIV-1 seropositive subjects with and without dementia.

1996 • 125 citations

Biochemical changes in the frontal lobe of HIV-infected individuals detected by magnetic resonance spectroscopy

1997 • 120 citations

Proton MR spectroscopy of HIV-infected patients: characterization of abnormalities with imaging and clinical correlation.

1993 • 119 citations

Elimination of artifacts in short echo time ¹H MR spectroscopy of the frontal lobe

1996 • 95 citations

HIV-1 Associated Dementia: Clinical Features and Pathogenesis

1995 • 94 citations

Prospective Utility of Cerebral Proton Magnetic Resonance Spectroscopy in Monitoring HIV Infection and Its Associated Neurological Impairment

1994 • 64 citations

Single-photon emission computed tomography in human immunodeficiency virus encephalopathy: a preliminary report.

1991 • 54 citations

In Vivo Magnetic Resonance Spectroscopy in HIV and HIV-Related Brain Diseases

1995 • 44 citations

Proton Spectroscopy in Asymptomatic HIV-Infected Adults: Initial Results in a Prospective Cohort Study

1996 • 42 citations

Improved Pulse Program for Long-Range Heteronuclear Correlation

1993 • 38 citations

Functional and Morphological Findings in Early and Advanced Stages of HIV Infection: a Comparison of 99mTc-HMPAO SPECT with CT and MRI Studies

1990 • 36 citations

The management of the neurological complications of HIV infection and AIDS

1988 • 32 citations

Issues in the evaluation of AIDS vaccines.

1988 • 12 citations

New Knockout Mice Point to Molecular Basis of Memory

1997 • 12 citations