Inhibition of Rev-Mediated HIV-1 Expression by an RNA Binding Protein Encoded by the Interferon-Inducible 9-27 Gene

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

1984 • 729 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.

1988 • 583 citations

A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

1989 • 536 citations

HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence

1990 • 457 citations

Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1

1990 • 430 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Regulation of human immunodeficiency virus env expression by the rev gene product

1989 • 365 citations

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region

1989 • 359 citations

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

1986 • 358 citations

Interferon-α But Not AZT Suppresses HIV Expression in Chronically Infected Cell Lines

1989 • 339 citations

THE BIOCHEMISTRY OF AIDS

1991 • 332 citations

RECOMBINANT HUMAN INTERFERON ALFA-A SUPPRESSES HTLV-III REPLICATION IN VITRO

1985 • 306 citations

Role of Mononuclear Phagocytes in the Pathogenesis of Human Immunodeficiency Virus Infection

1990 • 277 citations

Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein

1992 • 276 citations

Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression

1992 • 267 citations

A single DNA response element can confer inducibility by both alpha- and gamma-interferons.

1989 • 262 citations

A mechanism for the control of protein synthesis by adenovirus VA RNAI

1986 • 256 citations

Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs.

1991 • 232 citations

Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type I

1992 • 217 citations

SEPTICÆMIA DUE TO PORCINE STREPTOCOCCI

1975 • 212 citations

The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs.

1992 • 208 citations

Patients at Risk for AIDS-Related Opportunistic Infections

1985 • 197 citations

Secondary Structure is the Major Determinant for Interaction of HIV rev Protein with RNA

1990 • 188 citations

CLINICAL AND VIROLOGICAL EFFECTS OF HIGH-DOSE RECOMBINANT INTERFERON-α IN DISSEMINATED AIDS-RELATED KAPOSI'S SARCOMA

1988 • 187 citations

Molecular analysis of a human interferon‐inducible gene family

1991 • 186 citations

Transcriptional regulation of interferon‐stimulated genes

1991 • 184 citations

Adenovirus VAI RNA complexes with the 68 000 Mr protein kinase to regulate its autophosphorylation and activity.

1987 • 181 citations

Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation

1991 • 168 citations

Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA.

1991 • 163 citations

Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression

1991 • 160 citations

Alpha interferon inhibits early stages of the human immunodeficiency virus type 1 replication cycle

1992 • 159 citations

Functional Analysis of CAR, the Target Sequence for the Rev Protein of HIV-1

1989 • 152 citations

Regulation of HIV replication in infected monocytes by IFN-alpha. Mechanisms for viral restriction.

1990 • 134 citations

Restricted replication of lentiviruses. Visna viruses induce a unique interferon during interaction between lymphocytes and infected macrophages.

1985 • 127 citations

Commentary from Westminster

1983 • 126 citations

Transcription of interferon-stimulated genes is induced by adenovirus particles but is suppressed by E1A gene products

1988 • 124 citations

Interferons in the Persistence, Pathogenesis, and Treatment of HIV Infection

1992 • 123 citations

Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.

1990 • 119 citations

Interferon-gamma concentrations are increased in sera from individuals infected with human immunodeficiency virus type 1.

1989 • 119 citations

Immunological variables as predictors of prognosis in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome.

1986 • 108 citations

Interferon Production in Patients Infected with HIV-1

1989 • 100 citations

The role of interferons in the control of HIV replication in macrophages

1990 • 93 citations

Adenovirus early region 1A modulation of interferon antiviral activity

1987 • 79 citations

Interferon and Other Biologic Agents for the Treatment of Kaposi's Sarcoma

1991 • 79 citations

The control of interferon‐inducible gene expression

1991 • 73 citations

The HIV-1 Rev protein: a model system for coupled RNA transport and translation.

1991 • 69 citations

Tat and Rev

1990 • 64 citations

Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1

1990 • 63 citations

Lentivirus-induced interferon inhibits maturation and proliferation of monocytes and restricts the replication of caprine arthritis-encephalitis virus

1989 • 56 citations

Spontaneous interferon production by pulmonary leukocytes is associated with lentivirus-induced lymphoid interstitial pneumonia.

1988 • 44 citations

Zidovudine-Interferon- Combination Therapy in Patients with Advanced Human Immunodeficiency Virus Type 1 Infection: Biphasic Response of p24 Antigen and Quantitative Polymerase Chain Reaction

1992 • 36 citations

Interferon and interferon inhibitor levels in patients infected with varicella-zoster virus, acquired immunodeficiency syndrome, acquired immunodeficiency syndrome-related complex, or kaposi's sarcoma, and in normal individuals

1989 • 35 citations

Transcriptional activation of the tat-defective human immunodeficiency virus type-1 provirus: Effect of interferon

1992 • 22 citations

Regulation of Gene Expression in the Human Immunodeficiency Virus Type 1

1991 • 17 citations

2',5'-Oligoadenylate synthetase, neopterin and β2-microglobulin in asymptomatic HIV-infected individuals

1991 • 16 citations