Adenovirus VAI RNA complexes with the 68 000 Mr protein kinase to regulate its autophosphorylation and activity.

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis

1977 • 750 citations

Two small RNAs encoded by Epstein-Barr virus and complexed with protein are precipitated by antibodies from patients with systemic lupus erythematosus.

1981 • 577 citations

Interferon-mediated protein kinase and low-molecular-weight inhibitor of protein synthesis

1976 • 435 citations

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1985 • 383 citations

Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase

1986 • 358 citations

Interferon, double-stranded RNA, and protein phosphorylation.

1976 • 328 citations

Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII.

1981 • 315 citations

The Regulation of Initiation of Mammalian Protein Synthesis

1981 • 266 citations

Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells.

1979 • 263 citations

A mechanism for the control of protein synthesis by adenovirus VA RNAI

1986 • 256 citations

The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates

1975 • 254 citations

Specific phosphorylation in vitro of a protein associated with ribosomes of interferon‐treated mouse L cells

1976 • 238 citations

Inhibition of HeLa cell protein synthesis during adenovirus infection

1979 • 236 citations

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport.

1985 • 234 citations

Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation.

1983 • 203 citations

A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation.

1983 • 177 citations

2B or not 2B: Regulation of the catalytic utilization of elF-2

1983 • 172 citations

Purification and properties of poliovirus double-stranded ribonucleic acid

1966 • 171 citations

RNA of low molecular weight in KB cells infected with adenovirus type 2

1966 • 162 citations

Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI

1985 • 157 citations

Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2.

1980 • 157 citations

Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection.

1985 • 155 citations

Interaction between VA RNA and the lupus antigen La: formation of a ribonucleoprotein particle in vitro.

1982 • 154 citations

Effect of Adenovirus on Metabolism of Specific Host mRNAs: Transport Control and Specific Translational Discrimination

1983 • 151 citations

Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vectors.

1985 • 142 citations

Intracellular Uncoating of Type 5 Adenovirus Deoxyribonucleic Acid

1967 • 141 citations

Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells.

1985 • 138 citations

Striking Similarities Are Exhibited by Two Small Epstein-Barr Virus-Encoded Ribonucleic Acids and the Adenovirus-Associated Ribonucleic Acids VAI and VAII

1981 • 129 citations

Interferon, double-stranded RNA, and protein phosphorylation. Characteristics of a double-stranded RNA-activated protein kinase system partially purified from interferon treated Ehrlich ascites tumor cells.

1978 • 128 citations

Adenovirus E1B Proteins Are Required for Accumulation of Late Viral mRNA and for Effects on Cellular mRNA Translation and Transport

1985 • 117 citations

La Antigen Recognizes and Binds to the 3′-Oligouridylate Tail of a Small RNA

1984 • 115 citations

Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinase

1984 • 114 citations

Two small RNAs encoded by Epstein-Barr virus can functionally substitute for the virus-associated RNAs in the lytic growth of adenovirus 5.

1983 • 113 citations

Resistance of vaccinia virus to interferon is related to an interference phenomenon between the virus and the interferon system

1984 • 113 citations

Interferon-mediated, double-stranded RNA-dependent protein kinase is inhibited in extracts from vaccinia virus-infected cells

1984 • 101 citations

Translational control by influenza virus: suppression of the kinase that phosphorylates the alpha subunit of initiation factor eIF-2 and selective translation of influenza viral mRNAs.

1986 • 92 citations

Inhibition of Host Protein Synthesis in Type 5 Adenovirus-infected Cells

1967 • 89 citations

Cellular mRNA translation is blocked at both initiation and elongation after infection by influenza virus or adenovirus

1986 • 88 citations

Construction and analysis of additional adenovirus substitution mutants confirm the complementation of VAI RNA function by two small RNAs encoded by Epstein-Barr virus

1985 • 79 citations

Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA

1985 • 78 citations

Adenovirus VA RNAI mediates a translational stimulation which is not restricted to the viral mRNAs.

1985 • 77 citations

Binding of adenovirus VA RNA to mRNA: a possible role in splicing?

1980 • 76 citations

Adenovirus VA RNAI: a positive regulator of mRNA translation.

1984 • 66 citations

Synthesis of Complementary RNA Sequences During Productive Adenovirus Infection

1974 • 66 citations

Nuclear-cytoplasmic transport and VAI RNA-independent translation of influenza viral messenger RNAs in late adenovirus-infected cells

1984 • 59 citations

Studies of low molecular weight RNA from cells infected with adenovirus 2. II. Heterogeneity at the 5' end of VA-RNA I.

1977 • 55 citations

The conformation of adenovirus VAI-RNA in solution

1981 • 45 citations

Structural requirements of adenovirus VAI RNA for its translation enhancement function.

1985 • 44 citations

Synthesis and processing of simian virus 40-specific RNA in adenovirus-infected, simian virus 40-transformed human cells

1983 • 39 citations

Translational Control by Influenza Virus: Suppression of the Kinase That Phosphorylates the Alpha Subunit of Initiation Factor eIF-2 and Selective Translation of Influenza Viral mRNAs

1986 • 30 citations

Adenovirus VA RNA_I: a Positive Regulator of mRNA Translation

1984 • 28 citations

Structural Requirements of Adenovirus VAI RNA for Its Translation Enhancement Function

1985 • 27 citations