Real-time imaging of intrinsic optical signals during early excitotoxicity evoked by domoic acid in the rat hippocampal slice

Cloned Glutamate Receptors

1994 • 3,989 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Functional architecture of cortex revealed by optical imaging of intrinsic signals

1986 • 1,246 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

Anatomical organization of excitatory amino acid receptors and their pathways

1987 • 877 citations

An Outbreak of Toxic Encephalopathy Caused by Eating Mussels Contaminated with Domoic Acid

1990 • 726 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Neurologic Sequelae of Domoic Acid Intoxication Due to the Ingestion of Contaminated Mussels

1990 • 555 citations

AMPA and kainate receptors

1995 • 460 citations

Identification of domoic acid, a neuroexcitatory amino acid, in toxic mussels from eastern Prince Edward Island

1989 • 419 citations

Mechanisms of excitotoxicity in neurologic diseases

1992 • 382 citations

Changes in neuron structure during action potential propagation and synaptic transmission.

1973 • 339 citations

Imaging of synaptically evoked intrinsic optical signals in hippocampal slices

1991 • 302 citations

Imaging cell volume changes and neuronal excitation in the hippocampal slice

1994 • 302 citations

Opacity changes in stimulated nerve

1949 • 251 citations

Intrinsic optical signals in rat neocortical slices measured with near- infrared dark-field microscopy reveal changes in extracellular space

1996 • 219 citations

Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures

1989 • 169 citations

Effects of membrane depolarization on light scattering by cerebral cortical slices

1973 • 163 citations

Domoic acid: A dementia-inducing excitotoxic food poison with kainic acid receptor specificity

1990 • 150 citations

Kainic acid produces depolarization of CA3 pyramidal cells in the in vitro hippocampal slice

1981 • 148 citations

Treatment with an AMPA Antagonist 12 Hours following Severe Normothermic Forebrain Ischemia Prevents CA₁ Neuronal Injury

1993 • 148 citations

Cerebroprotective effect of a non-N-methyl-D-aspartate antagonist, GYKI 52466, after focal ischemia in the rat.

1992 • 145 citations

Carrier-mediated KCl accumulation accompanied by water movements is involved in the control of physiological K+ levels by astrocytes

1985 • 143 citations

Blockade of both NMDA and non-NMDA receptors is required for optimal protection against ischemic neuronal degeneration in the in vivo adult mammalian retina

1991 • 142 citations

The volume change resulting from stimulation of a giant nerve fibre

1950 • 137 citations

High‐affinity kainate a domoate receptors in rat brain

1992 • 135 citations

Quantitative autoradiography of binding sites for [3H]AMPA, a structural analogue of glutamic acid

1984 • 135 citations

Hippocampal damage produced by systemic injections of domoic acid in mice

1991 • 135 citations

Interaction of domoic acid and several derivatives with kainic acid and AMPA binding sites in rat brain

1992 • 130 citations

Depressant actions of γ-d-glutamylaminomethyl sulfonate (GAMS) on amino acid-induced and synaptic excitation in the cat spinal cord

1985 • 113 citations

Optical Imaging of Cortical Activity: Real-time imaging using extrinsic dye-signals and high resolution imaging based on slow intrinsic-signals

1989 • 97 citations

Domoic and quisqualic acids as potent amino acid excitants of frog and rat spinal neurones

1975 • 96 citations

Excitotoxicity: An overview

1990 • 93 citations

Changes in light scattering associated with the action potential in crab nerves

1971 • 91 citations

AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?

1993 • 88 citations

Kynurenic Acid: A Potential Pathogen in Brain Disorders^a

1992 • 79 citations

Imaging NMDA- and kainate-induced intrinsic optical signals from the hippocampal slice

1996 • 76 citations

Mapping patterns of neuronal activity and seizure propagation by imaging intrinsic optical signals in the isolated whole brain of the guinea-pig

1994 • 76 citations

A transmembrane sodium cycle in astrocytes

1986 • 66 citations

Excitotoxins: Possible Mechanisms of Action^a

1992 • 60 citations

Characterization of the pharmacology and regional distribution of (S)‐[³H]‐5‐fluorowillardiine binding in rat brain

1995 • 59 citations

Light transmittance as an index of cell volume in hippocampal slices: optical differences of interfaced and submerged positions

1995 • 55 citations

Glutamate-Mediated Excitotoxic Death of Cultured Striatal Neurons Is Mediated by Non-NMDA Receptors

1995 • 52 citations

Channel shutdown: a response of hippocampal neurons to adverse environments

1993 • 33 citations

Direct observation of neurotoxicity in brain slices with infrared videomicroscopy

1993 • 32 citations

Therapeutic Potential of AMPA Receptor Ligands in Neurological Disorders

1996 • 31 citations

Protection by Two Non-NMDA Antagonists, NBQX and GYKI 52466 Against Selective Cell Loss following Transient Global Ischaemia (4VO) in the Rat

1992 • 29 citations

Optical mapping of translucence changes in rat hippocampal slices during hypoxia

1995 • 27 citations

γ-d-glutamylaminomethyl sulfonic acid (GAMS) distinguishes kainic acid- from AMPA-induced responses in Xenopus oocytes expressing chick brain glutamate receptors

1993 • 21 citations

Anticonvulsant action of stereoisomers of γ-glutamylaminomethylsulphonic acid in mice

1985 • 18 citations

Kynurenic acid protects against neurotoxicity and lethality of toxic extracts from contaminated atlantic coast mussels

1989 • 15 citations

Analysis of the CCK_B receptor antagonism of virginiamycin in guinea‐pig ileum longitudinal myenteric plexus

1993 • 8 citations

Influence of rhein anthrone on peristaltic reflex of guinea‐pig isolated ileum: involvement of prostaglandins

1993 • 8 citations

Delayed increase of cell volume of single pyramidal cells in live rat hippocampal slices upon kainate application

1995 • 6 citations

Kynurenate antagonism of domoic acid-provoked EEG seizure activity in the mouse

1990 • 4 citations