Colony stimulating factors, cytokines and monocyte-macrophages-some controversies

Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis

1990 • 963 citations

Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

1992 • 841 citations

Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1

1986 • 781 citations

How important are t cells in chronic rheumatoid synovitis?

1990 • 553 citations

Inflammatory and immunomodulatory roles of TGF-β

1989 • 450 citations

Macrophage growth factor CSF-1 stimulates human monocyte production of interferon, tumor necrosis factor, and colony stimulating activity.

1986 • 397 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Modulation of cytokine production by transforming growth factor-beta.

1989 • 331 citations

Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhancing the function of antigen-presenting cells.

1987 • 299 citations

Regulation of tumor necrosis factor/cachectin and IL-1 secretion in human mononuclear phagocytes.

1988 • 278 citations

Production of lymphocyte-activating factor (Interleukin 1) by macrophages activated with colony-stimulating factors.

1980 • 272 citations

Expression of the M-CSF (CSF-1) gene by human monocytes

1987 • 238 citations

Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages

1988 • 234 citations

Granulocyte-macrophage colony-stimulating factor activates macrophages derived from bone marrow cultures to synthesis of MHC class II molecules and to augmented antigen presentation function.

1988 • 227 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor- dependent mechanism

1988 • 221 citations

Production of interleukin-1 receptor antagonist and interleukin-1 beta by peripheral blood mononuclear cells is differentially regulated

1991 • 201 citations

Independent regulation of M-CSF and G-CSF gene expression in human monocytes

1988 • 200 citations

Recombinant human granulocyte/macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor alpha and interferon in cancer patients

1989 • 185 citations

Human granulocyte-macrophage colony-stimulating factor induces expression of the tumor necrosis factor gene by the U937 cell line and by normal human monocytes.

1987 • 178 citations

Regulation of the expression of IL-6 in human monocytes.

1989 • 176 citations

Expression of the macrophage-specific colony-stimulating factor in human monocytes treated with granulocyte-macrophage colony-stimulating factor

1987 • 169 citations

Induction of the interleukin 1 receptor antagonist protein by transforming growth factor‐β

1991 • 167 citations

Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte- macrophage colony-stimulating factor [see comments]

1988 • 165 citations

Synergistic activation of human monocytes by granulocyte-macrophage colony-stimulating factor and IFN-gamma. Increased TNF-alpha but not IL-1 activity.

1988 • 139 citations

Regulation of Granulocyte- and Monocyte-colony Stimulating Factor mRNA Levels in Human Blood Monocytes Is Mediated Primarily at a Post-transcriptional Level

1989 • 139 citations

Macrophage activation by granulocyte/macrophage colony-stimulating factor. Priming for enhanced release of tumor necrosis factor-alpha and prostaglandin E2.

1989 • 136 citations

Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: Stimulation by endotoxin, M-CSF and multi-CSF

1985 • 124 citations

Control by IFN-gamma and PGE2 of TNF alpha and IL-1 production by human monocytes.

1989 • 123 citations

Interleukin-4 induces secretion of CSF for granulocytes and CSF for macrophages by peripheral blood monocytes

1989 • 103 citations

Production of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor by human mononuclear cells stimulated with granulocyte- macrophage colony-stimulating factor [see comments]

1988 • 103 citations

Contrasting effects of interferon-gamma and interleukin-4 on the interleukin-6 activity of stimulated human monocytes.

1990 • 94 citations

Interferon blocks interleukin 1-induced prostaglandin release from human peripheral monocytes.

1987 • 91 citations

Production of macrophage‐, granulocyte‐, granulocyte‐macrophage‐ and multi‐colony‐stimulating factor by peripheral blood cells

1989 • 83 citations

Transforming growth factor beta downregulates interleukin-1 (IL-1)- induced IL-6 production by human monocytes

1990 • 77 citations

Granulocyte-macrophage colony-stimulating factor stimulates human monocyte accessory cell function.

1990 • 75 citations

Granulocyte-macrophage colony-stimulating factor (CSF) and multilineage CSF recruit human monocytes to express granulocyte CSF

1989 • 75 citations

Differential Expression of M-CSF, G-CSF, and GM-CSF by Human Monocytes

1990 • 72 citations

Recombinant and native human urinary colony-stimulating factor directly augments granulocytic and granulocyte-macrophage colony-stimulating factor production of human peripheral blood monocytes.

1989 • 70 citations

Biochemical events accompanying macrophage activation and the inhibition of colony‐stimulating factor‐1‐induced macrophage proliferation by tumor necrosis factor‐α, interferon‐γ, and lipopolysaccharide

1992 • 63 citations

T cell-monocyte interactions in the production of humoral factors regulating human granulopoiesis in vitro.

1986 • 62 citations

Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-2, interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α) and IL-6 on the production of immunoreactive IL-1 and TNF-α by human monocytes

1991 • 56 citations

Activation and proliferation signals in murine macrophages. Biochemical signals controlling the regulation of macrophage urokinase-type plasminogen activator activity by colony-stimulating factors and other agents

1991 • 54 citations

Release of granulocyte-macrophage colony stimulating factors from major histocompatibility complex class II antigen-positive monocytes is enhanced by human gamma interferon

1985 • 51 citations

Mode of action of human urinary colony-stimulating factor.

1986 • 50 citations

Human T cells and interleukin 4 inhibit the release of interleukin 1 induced by lipopolysaccharide in serumfree cultures of autologous monocytes

1989 • 49 citations

Granulocyte-macrophage colony stimulating factor induces both HLA-DR expression and cytokine production by human monocytes

1990 • 48 citations

Regulation of macrophage activation by IL-3. II. IL-3 and lipopolysaccharide act synergistically in the regulation of IL-1 expression.

1990 • 47 citations

Activation of human monocytes by granulocyte-macrophage colony- stimulating factor: increased urokinase-type plasminogen activator activity

1991 • 46 citations

Enhancement of release from MHC class II antigen-positive monocytes of hematopoietic colony stimulating factors CSF-1 and G-CSF by recombinant human tumor necrosis factor-alpha: synergism with recombinant human interferon-gamma

1988 • 44 citations

Interleukin-4 suppresses granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor levels in stimulated human monocytes.

1992 • 41 citations

Interleukin-3 enhances cytokine production by LPS-stimulated macrophages

1991 • 32 citations

Interleukin-1 beta (IL-1 beta) expression in human blood mononuclear phagocytes is differentially regulated by granulocyte-macrophage colony- stimulating factor (GM-CSF), M-CSF, and IL-3

1992 • 29 citations

Heterogeneity in Responses of Human Blood Monocytes to Granulocyte-Macrophage Colony-Stimulating Factor

1990 • 26 citations

Synergistic interaction of bacterial lipopolysaccharide and the monocyte-macrophage colony-stimulating factor: potential quantitative and qualitative changes in macrophage-produced cytokine bioactivity

1992 • 26 citations

Interleukin‐4 prevents the induction of G‐CSF mRNA in human adherent monocytes in response to endotoxin and IL‐1 stimulation

1991 • 26 citations

Interleukin-1 beta (IL-1 beta) expression in human blood mononuclear phagocytes is differentially regulated by granulocyte-macrophage colony- stimulating factor (GM-CSF), M-CSF, and IL-3

1992 • 24 citations

Regulation of murine mononuclear phagocyte inflammatory products by macrophage colony-stimulating factor. Lack of IL-1 and prostaglandin E2 production and generation of a specific IL-1 inhibitor.

1991 • 23 citations

Regulation by interleukin-3 of human monocyte pro-inflammatory mediators. Similarities with granulocyte-macrophage colony-stimulating factor.

1990 • 19 citations

Regulation of Systemic Macrophage IL-1 Gene Transcription: The Involvement of Tumor-Derived Macrophage Growth Factor, CSF-1

1989 • 19 citations

Interferon-γ Potentiation of Lipopolysaccharide-Induced Eicosanoid Release from Human Monocytes

1987 • 19 citations

TNFα, IL-1α and bFGF are Implicated in the Complex Disease of GM-CSF Transgenic Mice

1992 • 13 citations