Granulocyte Colony-Stimulating Factor and Granulocyte-Macrophage Colony-Stimulating Factor

Proposals for the classification of the myelodysplastic syndromes

1982 • 3,616 citations

Quantitative Relationships Between Circulating Leukocytes and Infection in Patients with Acute Leukemia

1966 • 2,470 citations

Reduction by Granulocyte Colony-Stimulating Factor of Fever and Neutropenia Induced by Chemotherapy in Patients with Small-Cell Lung Cancer

1991 • 1,401 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Human GM-CSF: Molecular Cloning of the Complementary DNA and Purification of the Natural and Recombinant Proteins

1985 • 1,253 citations

Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium

1988 • 961 citations

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

1992 • 900 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Reconstitution after High-Dose Chemotherapy and Autologous Bone Marrow Transplantation

1988 • 779 citations

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR TO HARVEST CIRCULATING HAEMOPOIETIC STEM CELLS FOR AUTOTRANSPLANTATION

1989 • 776 citations

EFFECT OF GRANULOCYTE COLONY STIMULATING FACTOR ON NEUTROPENIA INDUCED BY CYTOTOXIC CHEMOTHERAPY

1988 • 740 citations

Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Chemotherapy-Induced Myelosuppression

1988 • 689 citations

Effects of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor in Patients with Myelodysplastic Syndromes

1987 • 653 citations

Effect of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor on Myelopoiesis in the Acquired Immunodeficiency Syndrome

1987 • 633 citations

Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer

1987 • 605 citations

Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients

1988 • 600 citations

GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR EXPANDS THE CIRCULATING HAEMOPOIETIC PROGENITOR CELL COMPARTMENT IN MAN

1988 • 585 citations

Recombinant Granulocyte-Macrophage Colony-Stimulating Factor after Autologous Bone Marrow Transplantation for Lymphoid Cancer

1991 • 509 citations

Steel locus defines new multipotent growth factor

1990 • 509 citations

Hematopoietic Growth Factors

1989 • 465 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

GRANULOCYTE COLONY-STIMULATING FACTOR AND NEUTROPHIL RECOVERY AFTER HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS BONE MARROW TRANSPLANTATION

1989 • 440 citations

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates.

1987 • 428 citations

Effect of Granulocyte Colony-Stimulating Factor after Intensive Induction Therapy in Relapsed or Refractory Acute Leukemia

1990 • 403 citations

Review: Stratton Lecture 1990. Clinical implications of positive and negative hematopoietic stem cell regulators

1991 • 369 citations

Treatment of Cyclic Neutropenia with Granulocyte Colony-Stimulating Factor

1989 • 363 citations

Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay

1989 • 339 citations

The kinetics of human granulopoiesis following treatment with granulocyte colony-stimulating factor in vivo.

1989 • 337 citations

Levels of serum granulocyte colony-stimulating factor in patients with infections

1990 • 337 citations

Erythropoietin

1991 • 321 citations

Cloning, sequence, and expression of a human granulocyte/macrophage colony-stimulating factor.

1985 • 314 citations

Phase I/II study of recombinant human granulocyte-macrophage colony- stimulating factor in aplastic anemia and myelodysplastic syndrome

1988 • 301 citations

Aplastic Anemia

1982 • 294 citations

Various human hematopoietic growth factors (interleukin-3, GM-CSF, G- CSF) stimulate clonal growth of nonhematopoietic tumor cells [see comments]

1989 • 294 citations

Replication of human immunodeficiency virus in monocytes. Granulocyte/macrophage colony-stimulating factor (GM-CSF) potentiates viral production yet enhances the antiviral effect mediated by 3'-azido-2'3'-dideoxythymidine (AZT) and other dideoxynucleoside congeners of thymidine.

1989 • 293 citations

Recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndromes--a phase I/II trial

1989 • 293 citations

Differential effects of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in children with severe congenital neutropenia

1990 • 289 citations

The effects of GM-CSF and G-CSF in promoting growth of clonogenic cells in acute myeloblastic leukemia

1987 • 273 citations

Serum granulocyte colony-stimulating factor levels in healthy volunteers and patients with various disorders as estimated by enzyme immunoassay

1989 • 272 citations

Use of recombinant human granulocyte-macrophage colony-stimulating factor in autologous marrow transplantation for lymphoid malignancies

1988 • 271 citations

The use of granulocyte colony-stimulating factor to increase the intensity of treatment with doxorubicin in patients with advanced breast and ovarian cancer

1989 • 267 citations

Hemopoietic Growth Factors: A Review

1992 • 239 citations

Maintenance treatment of patients with myelodysplastic syndromes using recombinant human granulocyte colony-stimulating factor

1990 • 238 citations

Phase I study of granulocyte colony-stimulating factor in patients with transitional cell carcinoma of the urothelium.

1988 • 233 citations

Evidence for a novel in vivo control mechanism of granulopoiesis: mature cell-related control of a regulatory growth factor

1989 • 231 citations

Nonhematopoietic tumor cells express functional GM-CSF receptors

1989 • 212 citations

Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor

1987 • 211 citations

Treatment of Myelodysplastic Syndromes with Recombinant Human Granulocyte Colony-Stimulating Factor

1989 • 208 citations

Development of antibodies to unprotected glycosylation sites on recombinant human GM-CSF

1990 • 207 citations

Recombinant human granulocyte-macrophage colony-stimulating factor reduces hematologic toxicity and widens clinical applicability of high-dose cyclophosphamide treatment in breast cancer and non-Hodgkin's lymphoma.

1990 • 203 citations

Hematologic effects of recombinant human granulocyte colony-stimulating factor in patients with malignancy

1989 • 200 citations

Therapy for Neutropenia in Hairy Cell Leukemia with Recombinant Human Granulocyte Colony-Stimulating Factor

1988 • 196 citations

Effects of Bacterially Synthesized Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor in Patients with Advanced Malignancy

1989 • 194 citations

Granulocyte-macrophage colony-stimulating factor enhances neutrophil function in acquired immunodeficiency syndrome patients.

1988 • 193 citations

Stimulation of Myelopoiesis in Patients with Aplastic Anemia by Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

1988 • 188 citations

Recombinant human granulocyte colony-stimulating factor hastens granulocyte recovery after high-dose chemotherapy and autologous bone marrow transplantation in Hodgkin's disease.

1989 • 188 citations

In vitro and in vivo analysis of the effects of recombinant human granulocyte colony-stimulating factor in patients

1988 • 187 citations

Recombinant human granulocyte/macrophage colony-stimulating factor enhances monocyte cytotoxicity and secretion of tumor necrosis factor alpha and interferon in cancer patients

1989 • 185 citations

Treatment of chemotherapy-induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and duration of therapy.

1989 • 181 citations

Subcutaneous granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome: toxicity, pharmacokinetics, and hematological effects.

1989 • 179 citations

Hematopoietic responses in patients with advanced malignancy treated with recombinant human granulocyte-macrophage colony-stimulating factor.

1989 • 179 citations

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) as Adjunct Therapy in Relapsed Hodgkin Disease

1992 • 174 citations

Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse

1991 • 165 citations

Recombinant human GM-CSF induces leukocytosis and activates peripheral blood polymorphonuclear neutrophils in nonhuman primates

1987 • 164 citations

Effects of Human Granulocyte Colony-Stimulating Factor in a Patient with Idiopathic Neutropenia

1989 • 164 citations

Treatment of refractory aplastic anemia with recombinant human granulocyte-macrophage-colony-stimulating factor

1989 • 160 citations

Granulocyte colony-stimulating factor stimulates recovery of granulocytes in patients receiving dose-intensive chemotherapy without bone marrow transplantation.

1989 • 150 citations

Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1

1989 • 146 citations

Correction of granulocytopenia in Felty's syndrome by granulocyte- macrophage colony-stimulating factor. Simultaneous induction of interleukin-6 release and flare-up of the arthritis

1989 • 145 citations

Kinetics of human hemopoietic cells after in vivo administration of granulocyte-macrophage colony-stimulating factor.

1989 • 144 citations

Recombinant Human Granulocyte Colony Stimulating Factor: Molecular and Biological Characterization

1986 • 142 citations

Granulocyte-macrophage colony-stimulating factor induces the expression of the CD11b surface adhesion molecule on human granulocytes in vivo

1988 • 141 citations

Treatment of aplastic anemia in children with recombinant human granulocyte colony-stimulating factor

1991 • 138 citations

Human recombinant GM-CSF in allogeneic bone-marrow transplantation for leukaemia: double-blind, placebo-controlled trial

1990 • 138 citations

Combined therapy with recombinant granulocyte colony-stimulating factor and erythropoietin decreases hematologic toxicity from zidovudine

1991 • 133 citations

Increased biological activity of deglycosylated recombinant human granulocyte/macrophage colony-stimulating factor produced by yeast or animal cells.

1987 • 130 citations

Increased serum levels of granulocyte colony-stimulating factor in patients with severe congenital neutropenia

1991 • 127 citations

Pharmacokinetics of human granulocyte-macrophage colony-stimulating factor using a sensitive immunoassay

1988 • 124 citations

Escalated Therapy for Refractory Urothelial Tumors: Methotrexate- Vinblastine-Doxorubicin- Cisplatin Plus Unglycosylated Recombinant Human Granulocyte-macrophage Colony-Stimulating Factor

1990 • 118 citations

Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity.

1990 • 117 citations

In vivo administration of recombinant human granulocyte/macrophage colony-stimulating factor in acute lymphoblastic leukemia patients receiving purged autografts [see comments]

1989 • 113 citations

Granulocyte macrophage colony stimulating factor induced changes in cellular adhesion molecule expression and adhesion to endothelium: in‐vitro and in‐vivo studies in man

1989 • 108 citations

Quantitative enzyme immunoassay for human granulocyte colony stimulating factor (G-CSF)

1989 • 108 citations

Characterization of the clinical effects after the first dose of bacterially synthesized recombinant human granulocyte-macrophage colony- stimulating factor

1989 • 106 citations

Failure of recombinant human granulocyte-macrophage colony-stimulating factor therapy in aplastic anemia patients with very severe neutropenia

1988 • 103 citations

Subcutaneous recombinant granulocyte-macrophage colony-stimulating factor used as a single agent and in an alternating regimen with azidothymidine in leukopenic patients with severe human immunodeficiency virus infection [see comments]

1990 • 100 citations

Effect of recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome with excess blasts.

1989 • 100 citations

Granulocyte colony-stimulating factor receptors in human acute myelocytic leukemia

1989 • 99 citations

A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma.

1991 • 98 citations

Induction of proliferation of purified human myeloid progenitor cells: a rapid assay for granulocyte colony-stimulating factors

1984 • 93 citations

Phase I/II trial of recombinant human granulocyte-macrophage colony- stimulating factor following allogeneic bone marrow transplantation

1991 • 88 citations

Recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) given as daily short infusions – a phase I dose-toxicity study

1989 • 85 citations

High-dose melphalan and granulocyte-macrophage colony-stimulating factor for refractory multiple myeloma

1990 • 82 citations

GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease.

1989 • 80 citations

Interferon gamma and granulocyte/macrophage colony-stimulating factor inhibit growth and induce antigens characteristic of myeloid differentiation in small-cell lung cancer cell lines.

1986 • 78 citations

Effect of granulocyte-macrophage colony-stimulating factor on neutropenia and related morbidity induced by myelotoxic chemotherapy

1990 • 77 citations

Recombinant human granulocyte colony-stimulating factor in allogeneic bone marrow transplantation.

1989 • 73 citations

Treatment of poor-prognosis, newly diagnosed acute myeloid leukemia with ara-C and recombinant human granulocyte-macrophage colony- stimulating factor

1990 • 69 citations

Reversible thyroid dysfunction during treatment with GM-CSF

1991 • 68 citations

Effect of recombinant human granulocyte‐macrophage colony stimulating factor on progenitor cells in patients with advanced malignancies

1990 • 68 citations

Phase I study of intravenously administered bacterially synthesized granulocyte-macrophage colony-stimulating factor and comparison with subcutaneous administration.

1990 • 67 citations

Effect of granulocyte colony-stimulating factor on neutropenia due to chemotherapy for non-Hodgkin's lymphoma

1990 • 66 citations

The effect of recombinant human granulocyte macrophage colony- stimulating factor on neutrophil activation in patients with refractory carcinoma

1989 • 63 citations

Haemopoietic cell kinetics in humans treated with rGM‐CSF

1992 • 59 citations

A Phase I/II Trial of Zidovudine, Interferon- , and Granulocyte-Macrophage Colony-Stimulating Factor in the Treatment of Human Immunodeficiency Virus Type 1 Infection

1991 • 58 citations

Hematopoietic progenitors in cyclic neutropenia: effect of granulocyte colony-stimulating factor in vivo

1990 • 53 citations

Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in patients with refractory metastatic carcinoma

1989 • 52 citations

The effects of dose and route of the administration on the pharmacokinetics of granulocyte-macrophage colony-stimulating factor

1990 • 52 citations

Effect of zidovudine and granulocyte-macrophage colony-stimulating factor on human immunodeficiency virus replication in alveolar macrophages

1990 • 52 citations

Recombinant human granulocyte colony-stimulating factor increases circulating burst forming unit-erythron and red blood cell production in patients with severe human immunodeficiency virus infection

1990 • 51 citations

Granulocyte-macrophage colony-stimulating factor may inhibit neutrophil migration in vivo.

1989 • 48 citations

Granulocyte-macrophage colony stimulating factor (GM-CSF) after high-dose melphalan in patients with advanced colon cancer

1990 • 44 citations

Effect of recombinant granulocyte colony-stimulating factor (rG-CSF) on chemotherapy-induced neutropenia in patients with urogenital cancer

1991 • 43 citations

Comparison of intravenous versus subcutaneous recombinant human granulocyte-macrophage colony-stimulating factor in patients with primary myelodysplasia.

1991 • 42 citations

Mitoxantrone/high-dose ara-c and recombinant human gm-csf in the treatment of refractory non-hodgkin's lymphoma a pilot study

1990 • 41 citations

Enhancement of superoxide anion release by granulocytes harvested from patients receiving granulocyte‐macrophage colony‐stimulating factor

1989 • 38 citations

Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in patients with refractory metastatic carcinoma

1989 • 37 citations

Effect of recombinant GM-CSF and recombinant G-CSF on colony formation of blast progenitors in acute myeloblastic leukemia.

1989 • 37 citations

Recombinant Granulocyte Colony-Stimulating Factor (rG-CSF)

1992 • 35 citations

Serum levels of tumor necrosis factor alpha in patients treated with granulocyte-macrophage colony-stimulating factor [letter; comment]

1990 • 31 citations

The dissociation of GM‐CSF efficacy from toxicity according to route of administration: a pharmacodynamic study

1992 • 28 citations

DIFFERENTIAL EFFECT OF G‐CSF AND GM‐CSF IN ACQUIRED CHRONIC NEUTROPENIA

1991 • 27 citations

Serum levels of tumor necrosis factor alpha in patients treated with granulocyte-macrophage colony-stimulating factor [letter; comment]

1990 • 19 citations

Serum cholesterol-lowering activity of granulocyte-macrophage colony-stimulating factor

1988 • 14 citations

Measuring the cost-effectiveness of hematopoietic growth factor therapy

1991 • 13 citations

Serum Granulocyte Colony-Stimulating Factor Levels in Chronic Neutropenia of Infancy

1990 • 12 citations

Influence of GM-CSF-schedule on post-chemotherapy myelosuppression

1991 • 3 citations

Medical and economic implications of hematopoietic colony-stimulating factor use in oncology

1991 • 2 citations

Correction

1992 • 1 citations

Deleted Work

1955 • 0 citations