Glycoprotein contributions to mammary gland and mammary tumor structure and function: Roles of adherens junctions, ErbBs and membrane MUCs

Untangling the ErbB signalling network

2001 • 6,623 citations

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Regulation of Cadherin Adhesive Activity

2000 • 793 citations

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor.

1994 • 712 citations

The organizing principle: microenvironmental influences in the normal and malignant breast

2002 • 603 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Regulation of E-cadherin/Catenin Association by Tyrosine Phosphorylation

1999 • 589 citations

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

2001 • 559 citations

MUC1, the renaissance molecule.

2001 • 545 citations

New Perspectives on Mechanisms Involved in Generating Epithelial Cell Polarity

1999 • 522 citations

Decreased Accessibility and Lack of Activation of ErbB2 in JIMT-1, a Herceptin-Resistant, MUC4-Expressing Breast Cancer Cell Line

2005 • 494 citations

CD44 anchors the assembly of matrilysin/MMP-7 with heparin-binding epidermal growth factor precursor and ErbB4 and regulates female reproductive organ remodeling

2002 • 472 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Molecular organization of the uvomorulin-catenin complex.

1992 • 378 citations

Peroxynitrite Inhibits Glutamate Transporter Subtypes

1996 • 375 citations

The E-cadherin–catenin complex in tumour metastasis

2000 • 347 citations

p120 Catenin-Associated Fer and Fyn Tyrosine Kinases Regulate β-Catenin Tyr-142 Phosphorylation and β-Catenin-α-Catenin Interaction

2003 • 329 citations

Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes

2004 • 310 citations

Cell signaling through membrane mucins

2002 • 232 citations

The mammary gland and its origin during synapsid evolution.

2002 • 223 citations

Beta-catenin and Tcfs in mammary development and cancer.

2003 • 208 citations

An Intramembrane Modulator of the ErbB2 Receptor Tyrosine Kinase That Potentiates Neuregulin Signaling

1999 • 197 citations

The mammary gland: A unique organ for the study of development and tumorigenesis

1996 • 188 citations

The cadherin–catenin complex as a focal point of cell adhesion and signalling: new insights from three‐dimensional structures

2004 • 183 citations

c-erbB-2 Gene Product Directly Associates with β-Catenin and Plakoglobin

1995 • 165 citations

The MUC1 Oncoprotein Activates the Anti-apoptotic Phosphoinositide 3-Kinase/Akt and Bcl-xL Pathways in Rat 3Y1 Fibroblasts

2004 • 163 citations

Use of Three-Dimensional Basement Membrane Cultures to Model Oncogene-Induced Changes in Mammary Epithelial Morphogenesis

2004 • 148 citations

MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation

2004 • 147 citations

Density-Dependent Inhibition of Growth Involves Prevention of EGF Receptor Activation by E-Cadherin-Mediated Cell–Cell Adhesion

1996 • 142 citations

Transgenic mouse models of human breast cancer

2000 • 141 citations

Overexpression of sialomucin complex, a rat homologue of MUC4, inhibits tumor killing by lymphokine-activated killer cells.

1999 • 137 citations

Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27kip, but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways

2002 • 137 citations

Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor

2001 • 132 citations

ErbBs in mammary development

2003 • 123 citations

The biochemistry and physiology of the receptor-kinase for epidermal growth factor

1983 • 117 citations

Sialomucin Complex, a Heterodimeric Glycoprotein Complex

1996 • 117 citations

Molecular cloning of the transmembrane component of the 13762 mammary adenocarcinoma sialomucin complex. A new member of the epidermal growth factor superfamily.

1992 • 115 citations

Molecular complexity of vertebrate tight junctions (Review)

2002 • 113 citations

Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer

2004 • 112 citations

Muc4/sialomucin complex, the intramembrane Er6B2 ligand, in cancer and epithelia: To protect and to survive

2002 • 110 citations

Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer

2004 • 98 citations

A complex of two cell surface glycoproteins from ascites mammary adenocarcinoma cells.

1980 • 91 citations

Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein.

2003 • 89 citations

Muc4/Sialomucin Complex, the Intramembrane ErbB2 Ligand, Translocates ErbB2 to the Apical Surface in Polarized Epithelial Cells

2003 • 80 citations

Induction of ductal morphogenesis and lobular hyperplasia by amphiregulin in the mouse mammary gland.

1996 • 60 citations

Sialomucin complex in the rat respiratory tract: a model for its role in epithelial protection

1998 • 53 citations

Recruitment of Phosphoinositide 3-Kinase Defines a Positive Contribution of Tyrosine Kinase Signaling to E-cadherin Function

2004 • 52 citations

Synthesis and secretion of Muc4/sialomucin complex: implication of intracellular proteolysis

2002 • 46 citations

Expression, location, and interactions of ErbB2 and its intramembrane ligand Muc4 (sialomucin complex) in rat mammary gland during pregnancy

2004 • 32 citations

SMAD2 and SMAD7 Involvement in the Post-translational Regulation of Muc4 via the Transforming Growth Factor-β and Interferon-γ Pathways in Rat Mammary Epithelial Cells

2003 • 32 citations

Multidrug resistance correlates with overexpression of Muc4 but inversely with P-glycoprotein and multidrug resistance related protein in transfected human melanoma cells

2003 • 26 citations

The Cross-Rho'ds of Cell-Cell Adhesion

2004 • 25 citations

General Keynote: Expression of Epidermal Growth Factor Receptor Family in Transgenic Mouse Models of Human Breast Cancer

2003 • 5 citations

Deleted Work

1955 • 0 citations