Cell signaling through membrane mucins

Epithelial Mucin Genes

1995 • 982 citations

Mucin-Type Glycoproteins

1992 • 902 citations

A neu acquaintance for ErbB3 and ErbB4: A role for receptor heterodimerization in growth signaling

1994 • 601 citations

Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor Receptors

1999 • 548 citations

MUC1, the renaissance molecule.

2001 • 545 citations

The cadherin-catenin adhesion system in signaling and cancer

2002 • 541 citations

Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components.

1995 • 503 citations

Cell membrane-associated mucins and their adhesion-modulating property

1992 • 472 citations

The cadherin-catenin adhesion system in signaling and cancer

2002 • 448 citations

Mechanisms of apoptosis avoidance in cancer

1999 • 371 citations

Transgenic MUC1 Interacts with Epidermal Growth Factor Receptor and Correlates with Mitogen-activated Protein Kinase Activation in the Mouse Mammary Gland

2001 • 340 citations

Interaction of the DF3/MUC1 Breast Carcinoma-associated Antigen and β-Catenin in Cell Adhesion

1997 • 306 citations

The Yin-Yang of TCF/β-Catenin Signaling

1999 • 293 citations

ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor

2000 • 289 citations

The Epidermal Growth Factor Receptor Regulates Interaction of the Human DF3/MUC1 Carcinoma Antigen with c-Src and β-Catenin

2001 • 251 citations

Human epithelial tumor antigen cDNA sequences

1990 • 242 citations

Interaction of Glycogen Synthase Kinase 3β with the DF3/MUC1 Carcinoma-Associated Antigen and β-Catenin

1998 • 238 citations

Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism

1991 • 225 citations

The c-Src Tyrosine Kinase Regulates Signaling of the Human DF3/MUC1 Carcinoma-associated Antigen with GSK3β and β-Catenin

2001 • 219 citations

Rat Muc4 (sialomucin complex) reduces binding of anti‐ErbB2 antibodies to tumor cell surfaces, a potential mechanism for herceptin resistance

2002 • 200 citations

A single autophosphorylation site confers oncogenicity to the Neu/ErbB-2 receptor and enables coupling to the MAP kinase pathway.

1994 • 198 citations

An Intramembrane Modulator of the ErbB2 Receptor Tyrosine Kinase That Potentiates Neuregulin Signaling

1999 • 197 citations

Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein.

1995 • 188 citations

Reversible Disruption of Cell-Matrix and Cell-Cell Interactions by Overexpression of Sialomucin Complex

1997 • 167 citations

Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins Cytokine receptor‐like molecules

1994 • 155 citations

Protein Kinase C δ Regulates Function of the DF3/MUC1 Carcinoma Antigen in β-Catenin Signaling

2002 • 141 citations

Overexpression of sialomucin complex, a rat homologue of MUC4, inhibits tumor killing by lymphokine-activated killer cells.

1999 • 137 citations

Muc4/sialomucin complex, the intramembrane ErbB2 ligand, induces specific phosphorylation of ErbB2 and enhances expression of p27kip, but does not activate mitogen-activated kinase or protein kinaseB/Akt pathways

2002 • 137 citations

Muc4/sialomucin complex, an intramembrane modulator of ErbB2/HER2/Neu, potentiates primary tumor growth and suppresses apoptosis in a xenotransplanted tumor

2001 • 132 citations

Sialomucin Complex, a Heterodimeric Glycoprotein Complex

1996 • 117 citations

Molecular cloning of the transmembrane component of the 13762 mammary adenocarcinoma sialomucin complex. A new member of the epidermal growth factor superfamily.

1992 • 115 citations

Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins

2000 • 109 citations

The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail

1992 • 85 citations

Involvement of the MAP kinase ERK2 in MUC1 mucin signaling

2001 • 79 citations

Signaling, mitogenesis and the cytoskeleton: Where the action is

1995 • 76 citations

Multiple facets of sialomucin complex/MUC4, a membrane mucin and ErbB2 ligand, in tumors and tissues (Y2K update)

2000 • 73 citations

Wnt signaling and mammary tumorigenesis.

2001 • 73 citations

Sialomucin complex at the rat ocular surface: a new model for ocular surface protection

1998 • 63 citations

The Human DF3/MUC1 Carcinoma-Associated Antigen Signals Nuclear Localization of the Catenin p120ctn

2001 • 61 citations

Multiple protein forms of the human breast tumor-associated epithelial membrane antigen (EMA) are generated by alternative splicing and induced by hormonal stimulation

1990 • 50 citations

Sialomucin Complex (Muc4) Expression in the Rat Female Reproductive Tract1

1999 • 49 citations

Involvement of the neuregulins and their receptors in cardiac and neural development

1996 • 39 citations

Sialomucin complex in tumors and tissues

1997 • 39 citations

Construction and characterization of a chimeric receptor containing the cytoplasmic domain of MUC1 mucin

2000 • 32 citations

Regulation of sialomucin complex/Muc4 expression in rat uterine luminal epithelial cells by transforming growth factor-?: Implications for blastocyst implantation

2000 • 30 citations