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Echistatin is a potent inhibitor of bone resorption in culture.

Data up to Jan 2025

Published1990
Citations201
References34

Total Citations Per Year

Abstract

References (34)

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

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1987 • 4,322 citations

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1989 • 864 citations

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1988 • 380 citations

The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor.

1989 • 372 citations

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1988 • 365 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Cellular biology and biochemical mechanism of bone resorption. A review of recent developments on the formation, activation, and mode of action of osteoclasts.

1988 • 332 citations

Cell-substratum interaction of cultured avian osteoclasts is mediated by specific adhesion structures.

1984 • 324 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

Isolated osteoclasts resorb the organic and inorganic components of bone.

1986 • 276 citations

Effects of bisphosphonates on isolated Rat osteoclasts as examined by reflected light microscopy

1990 • 271 citations

Identification of a bone sialoprotein receptor in osteosarcoma cells.

1988 • 248 citations

Polarized secretion of lysosomal enzymes: co-distribution of cation-independent mannose-6-phosphate receptors and lysosomal enzymes along the osteoclast exocytic pathway.

1988 • 209 citations

Immunocytochemical distribution of extracellular matrix receptors in human osteoclasts: A β3 integrin is colocalized with vinculin and talin in the podosomes of osteoclastoma giant cells

1989 • 199 citations

Quantitative reflection contrast microscopy of living cells.

1979 • 194 citations

A Comparative Study of Disaggregated Chick and Rat Osteoclasts in Vitro: Effects of Calcitonin and Prostaglandins*

1987 • 181 citations

A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.

1989 • 167 citations

Trigramin: primary structure and its inhibition of von Willebrand factor binding to glycoprotein IIb/IIIa complex on human platelets

1989 • 161 citations

Osteoclastic bone resorption: In vitro analysis of the rate of resorption and migration of individual osteoclasts

1988 • 155 citations

Characterization and Platelet Inhibitory Activity of Bitistatin, a Potent Arginine-Glycine-Aspartic Acid-Containing Peptide from the Venom of the Viper Bitis arietans

1989 • 150 citations

Monoclonal antibodies against osteoclasts inhibit bone resorption in vitro.

1986 • 122 citations

Isolated osteoclasts in primary culture: first observations on structure and survival in culture media

1982 • 121 citations

Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp-containing peptide overproduce the fibronectin receptor.

1987 • 102 citations

Chemical synthesis of echistatin, a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs.

1989 • 100 citations

Adhesion patterns and cytoskeleton of rabbit osteoclasts on bone slices and glass

1988 • 87 citations

Trigramin, an RGD-containing peptide from snake venom, inhibits cell-substratum adhesion of human melanoma cells

1988 • 74 citations

The effect of fluoride on the patterns of adherence of osteoclasts cultured on and resorbing dentine: a 3-D assessment of vinculin-labelled cells using confocal optical microscopy

1989 • 42 citations

Evidence for capping of Fcγ receptors on osteoclasts

1986 • 25 citations

Contacts of chick fibroblasts on glass: Results and limitations of quantitative interferometry

1988 • 20 citations

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1989 • 12 citations

Deleted Work

1955 • 0 citations

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Echistatin is a potent inhibitor of bone resorption in culture. (1990) – The Journal of Cell Biology | Metascience Observatory Explorer