Effects induced by the antiepileptic drug valproic acid upon the ionic currents recorded in rat neocortical neurons in cell culture

Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons

1986 • 560 citations

EFFECTS OF DI‐n‐PROPYLACETATE, AN ANTICONVULSIVE COMPOUND, ON GABA METABOLISM¹

1969 • 394 citations

Mechanism of anticonvulsant action of valproate

1982 • 344 citations

Sodium valproate, but not ethosuximide, produces use- and voltage-dependent limitation of high frequency repetitive firing of action potentials of mouse central neurons in cell culture.

1986 • 272 citations

Low‐calcium field burst discharges of CA1 pyramidal neurones in rat hippocampal slices.

1984 • 269 citations

Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium

1986 • 229 citations

Mechanisms of interictal epileptogenesis.

1986 • 154 citations

Valproic Acid

1979 • 126 citations

Valproate induced changes in GABA metabolism at the subcellular level

1981 • 125 citations

Disposition of valproic acid in man

1977 • 121 citations

Calcium and epileptogenesis

1986 • 114 citations

Valproate Reduces Excitability by Blockage of Sodium and Potassium Conductance

1986 • 112 citations

Sodium Valproate Increases Potassium Conductance in Aplysia Neurons

1978 • 90 citations

Dissociation between drug-induced increases in nerve terminal and non-nerve terminal pools of GABA in vivo

1979 • 83 citations

The action of valproate on spontaneous epileptiform activity in the absence of synaptic transmission and on evoked changes in [Ca2+]0 and [K+]0 in the hippocampal slice

1986 • 75 citations

Sodium valproate enhancement of gamma-aminobutyric acid (GABA) inhibition: electrophysiological evidence for anticonvulsant activity.

1981 • 71 citations

Sodium di-n-propylacetate (valproate) potentiates responses to GABA and muscimol on single central neurones

1980 • 56 citations

Excitable channel currents and gating times in the presence of anticonvulsants ethosuximide and valproate.

1984 • 40 citations

Valproate enhances inhibitory postsynaptic potentials in hippocampal neurons in vitro

1987 • 39 citations

Delayed and fast transient potassium currents in rat neocortical neurons in cell culture

1988 • 32 citations

Sodium valproate decreases synaptic potentiation and epileptiform activity in hippocampus

1988 • 31 citations

Calcium currents in cultured rat cortical neurons

1989 • 31 citations

Testing of prototype antiepileptics in hippocampal slices

1986 • 27 citations

Failure of the antiepileptic drug valproic acid to modify synaptic and non-synaptic responses of CA1 hippocampal pyramidal cells maintained ‘in vitro’

1989 • 20 citations

Valproic acid serum levels and protection against kindled amygdaloid scizures in the rat

1981 • 17 citations

Depression of hippocampal low calcium field bursts by the antiepileptic drug valproic acid

1985 • 15 citations

Pre- and postsynaptic actions of valproic acid at the frog neuromuscular junction

1984 • 14 citations

Mechanisms of Anticonvulsant Action of Valproate: An Overview and Perspective

1990 • 11 citations