Frequency-dependent electrophysiologic properties of ventricular repolarization in patients with congenital long QT syndrome

On methods in the analysis of profile data

1959 • 4,777 citations

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

1995 • 2,391 citations

A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

1995 • 2,263 citations

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

1996 • 1,746 citations

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

1995 • 1,686 citations

Congenital deaf-mutism, functional heart disease with prolongation of the Q-T interval, and sudden death

1957 • 1,593 citations

Diagnostic criteria for the long QT syndrome. An update.

1993 • 1,160 citations

Nonuniform Recovery of Excitability in Ventricular Muscle

1964 • 939 citations

A NEW FAMILIAL CARDIAC SYNDROME IN CHILDREN.

1964 • 842 citations

Long QT Syndrome Patients With Mutations of the SCN5A and HERG Genes Have Differential Responses to Na ⁺ Channel Blockade and to Increases in Heart Rate

1995 • 801 citations

The long QT syndromes: A critical review, new clinical observations and a unifying hypothesis

1988 • 801 citations

Characteristics and possible mechanism of ventricular arrhythmia dependent on the dispersion of action potential durations.

1983 • 747 citations

ECG T-Wave Patterns in Genetically Distinct Forms of the Hereditary Long QT Syndrome

1995 • 618 citations

Linkage of a Cardiac Arrhythmia, the Long QT Syndrome, and the Harvey ras -1 Gene

1991 • 526 citations

Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide.

1993 • 512 citations

Cycle length dependence of human action potential duration in vivo. Effects of single extrastimuli, sudden sustained rate acceleration and deceleration, and different steady-state frequencies.

1988 • 459 citations

Dispersion of the QT interval. A marker of therapeutic efficacy in the idiopathic long QT syndrome.

1994 • 401 citations

Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report.

1991 • 375 citations

Electrophysiologic substrate of torsade de pointes: Dispersion of repolarization or early afterdepolarizations?

1989 • 276 citations

Two long QT syndrome loci map to chromosomes 3 and 7 with evidence for further heterogeneity

1994 • 270 citations

[RARE CARDIAC ARRYTHMIAS OF THE PEDIATRIC AGE. II. SYNCOPAL ATTACKS DUE TO PAROXYSMAL VENTRICULAR FIBRILLATION. (PRESENTATION OF 1ST CASE IN ITALIAN PEDIATRIC LITERATURE)].

1963 • 241 citations

Long-term recording of monophasic action potentials from human endocardium

1983 • 225 citations

Efficacy of permanent pacing in the management of high-risk patients with long QT syndrome.

1991 • 197 citations

Early afterdepolarizations induced by isoproterenol in patients with congenital long QT syndrome.

1991 • 180 citations

Assessment of QT dispersion in symptomatic patients with congenital long QT syndromes

1992 • 168 citations

Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome

1995 • 157 citations

Prolonged QT-Interval Syndromes

1986 • 150 citations

Electrophysiologic testing in patients with the long QT syndrome.

1985 • 150 citations

Combined use of beta-adrenergic blocking agents and long-term cardiac pacing for patients with the long QT syndrome

1992 • 146 citations

The Idiopathic Long QT Syndrome: Pathogenetic Mechanisms and Therapy

1985 • 146 citations

Heritable Q-T Prolongation Without Deafness

1970 • 122 citations

Differential Response of QTU Interval to Exercise, Isoproterenol, and Atrial Pacing in Patients with Congenital Long QT Syndrome

1991 • 64 citations

Autonomic maneuvers in hereditary Q-T interval prolongation (Romano-Ward syndrome)

1978 • 51 citations

Epinephrine‐Induced Ventricular Premature Complexes Due to Early Afterdepolarizations and Effects of Verapamil and Propranolol in a Patient with Congenital Long QT Syndrome

1994 • 50 citations

Diagnostic value of recovery time measured by body surface mapping in patients with congenital long QT syndrome

1994 • 47 citations

[Prolonged QT interval syndrome].

1983 • 19 citations