Back to search

Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may contribute to immune evasion

Data up to Jan 2025

Published2007
Citations229
References36

Total Citations Per Year

Abstract

References (36)

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1994 • 553 citations

Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis

2000 • 468 citations

Downregulation of Major Histocompatibility Complex Class I Molecules by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5 Proteins

2000 • 436 citations

A re‐examination of the epstein‐barr virus carrier state in healthy seropositive individuals

1985 • 336 citations

Epitope-specific Evolution of Human CD8+ T Cell Responses from Primary to Persistent Phases of Epstein-Barr Virus Infection

2002 • 310 citations

Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs.

1987 • 292 citations

Herpes Simplex Virus Virion Host Shutoff Protein: Immune Evasion Mediated by a Viral RNase?

2004 • 231 citations

Characterization of the CD4+ T Cell Response to Epstein-Barr Virus during Primary and Persistent Infection

2003 • 226 citations

Lytic KSHV Infection Inhibits Host Gene Expression by Accelerating Global mRNA Turnover

2004 • 223 citations

Inhibition of MHC class I-restricted antigen presentation by γ2-herpesviruses

2000 • 214 citations

Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing

2005 • 188 citations

Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis

1995 • 163 citations

Human herpes simplex virus (HSV)-specific CD8+ CTL clones recognize HSV-2-infected fibroblasts after treatment with IFN-gamma or when virion host shutoff functions are disabled.

1996 • 140 citations

Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond

2005 • 128 citations

Highly Selective Escape from KSHV-mediated Host mRNA Shutoff and Its Implications for Viral Pathogenesis

2004 • 115 citations

The Exonuclease and Host Shutoff Functions of the SOX Protein of Kaposi's Sarcoma-Associated Herpesvirus Are Genetically Separable

2005 • 108 citations

Interference with T cell receptor–HLA-DR interactions by Epstein–Barr virus gp42 results in reduced T helper cell recognition

2003 • 99 citations

Epstein-Barr Virus gp42 Is Posttranslationally Modified To Produce Soluble gp42 That Mediates HLA Class II Immune Evasion

2004 • 96 citations

Virus-specific CD4+ T cells: ready for direct attack

2006 • 88 citations

Epstein-Barr Virus mRNA Export Factor EB2 Is Essential for Production of Infectious Virus

2002 • 83 citations

The U L 41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins

2006 • 82 citations

The UL41-encoded virion host shutoff (vhs) protein and vhs-independent mechanisms are responsible for down-regulation of MHC class I molecules by bovine herpesvirus 1

2001 • 78 citations

The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules

2002 • 76 citations

Viral Regulation of mRNA Export

2004 • 74 citations

The Epstein–Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression

1998 • 72 citations

Impaired Transporter Associated with Antigen Processing-Dependent Peptide Transport during Productive EBV Infection

2005 • 66 citations

Herpes Simplex Virus Virion Host Shutoff (vhs) Activity Alters Periocular Disease in Mice

2000 • 54 citations

Comparison of exonucleolytic activities of herpes simplex virus type‐1 DNA polymerase and DNase

1990 • 52 citations

Disruption of Virion Host Shutoff Activity Improves the Immunogenicity and Protective Capacity of a Replication-Incompetent Herpes Simplex Virus Type 1 Vaccine Strain

2000 • 52 citations

The UL12.5 Gene Product of Herpes Simplex Virus Type 1 Exhibits Nuclease and Strand Exchange Activities but Does Not Localize to the Nucleus

2004 • 49 citations

The human cytomegalovirus UL98 gene encodes the conserved herpesvirus alkaline nuclease.

1997 • 31 citations

Functional Analysis of Epstein-Barr Virus SM Protein: Identification of Amino Acids Essential for Structure, Transactivation, Splicing Inhibition, and Virion Production

2003 • 28 citations

Epstein-Barr Virus (EBV) Replication and Expressions of EA-D (BMRF1 Gene Product), Virus-Specific Deoxyribonuclease, and DNA Polymerase in EBV-Activated Akata Cells

1993 • 19 citations

Site-directed mutagenesis in a conserved motif of Epstein–Barr virus DNase that is homologous to the catalytic centre of type II restriction endonucleases

2003 • 13 citations

Cited By (0)

Loading...
Host shutoff during productive Epstein–Barr virus infection is mediated by BGLF5 and may… (2007) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer