The U _L 41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins

Characterization of Herpes Simplex Virus Strains Differing in their Effects on Social Behaviour of Infected Cells

1968 • 874 citations

Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

2002 • 688 citations

Stressful initiations

2002 • 359 citations

Herpes simplex virus virion host shutoff function

1988 • 350 citations

Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs.

1987 • 292 citations

Herpes Simplex Virus Virion Host Shutoff Protein: Immune Evasion Mediated by a Viral RNase?

2004 • 231 citations

Control of mRNA stability by the virion host shutoff function of herpes simplex virus

1989 • 229 citations

mRNA Degradation by the Virion Host Shutoff (Vhs) Protein of Herpes Simplex Virus: Genetic and Biochemical Evidence that Vhs Is a Nuclease

2002 • 162 citations

Effects of herpes simplex virus on mRNA stability

1987 • 151 citations

Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs

1994 • 151 citations

The Herpes Simplex Virus vhs Protein Induces Endoribonucleolytic Cleavage of Target RNAs in Cell Extracts

1999 • 125 citations

Mitochondrial distribution and function in herpes simplex virus-infected cells

2000 • 108 citations

The virion host shutoff protein of herpes simplex virus type 1: messenger ribonucleolytic activity in vitro

1996 • 107 citations

Macromolecular Synthesis in Cells infected with Herpes Simplex Virus

1965 • 103 citations

The herpes simplex virus 1 U _L 41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific

2004 • 91 citations

RNAs Extracted from Herpes Simplex Virus 1 Virions: Apparent Selectivity of Viral but Not Cellular RNAs Packaged in Virions

2001 • 90 citations

An amino acid sequence shared by the herpes simplex virus 1 alpha regulatory proteins 0, 4, 22, and 27 predicts the nucleotidylylation of the UL21, UL31, UL47, and UL49 gene products

1994 • 89 citations

Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteins

1995 • 81 citations

Herpes Simplex Virus 1 Induces Cytoplasmic Accumulation of TIA-1/TIAR and both Synthesis and Cytoplasmic Accumulation of Tristetraprolin, Two Cellular Proteins That Bind and Destabilize AU-Rich RNAs

2004 • 80 citations

Herpes Simplex Virus Virion Host Shutoff Protein Is Stimulated by Translation Initiation Factors eIF4B and eIF4H

2004 • 74 citations

The U _L 41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs

2004 • 74 citations

The Virion Host Shutoff Function of Herpes Simplex Virus Degrades the 5′ End of a Target mRNA before the 3′ End

1999 • 74 citations

In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus

1991 • 71 citations

Picornavirus Internal Ribosome Entry Site Elements Target RNA Cleavage Events Induced by the Herpes Simplex Virus Virion Host Shutoff Protein

1999 • 64 citations

The Stress-Inducible Immediate-Early Responsive Gene IEX-1 Is Activated in Cells Infected with Herpes Simplex Virus 1, but Several Viral Mechanisms, Including 3′ Degradation of Its RNA, Preclude Expression of the Gene

2003 • 47 citations

The Virion Host Shutoff Protein of Herpes Simplex Virus Inhibits Reporter Gene Expression in the Absence of Other Viral Gene Products

1995 • 47 citations

Differentiation of the Shutoff of Protein Synthesis by Virion Host Shutoff and Mutant γ134.5 Genes of Herpes Simplex Virus 1

1997 • 45 citations

Site-Directed Mutagenesis of the Virion Host Shutoff Gene (UL41) of Herpes Simplex Virus (HSV): Analysis of Functional Differences between HSV Type 1 (HSV-1) and HSV-2 Alleles

1999 • 36 citations

Nuclear Localizations of the Herpes Simplex Virus Type 1 Tegument Proteins VP13/14, vhs, and VP16 Precede VP22-Dependent Microtubule Reorganization and VP22 Nuclear Import

2005 • 33 citations

Affinity purification of GST fusion proteins for immunohistochemical studies of gene expression

2002 • 23 citations

RNA Degradation Induced by the Herpes Simplex Virus vhs Protein Proceeds 5′ to 3′ In Vitro

2004 • 19 citations