Evidence of a role for TRPC channels in VEGF-mediated increased vascular permeability in vivo

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1991 • 2,499 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

STUDIES ON INFLAMMATION

1961 • 1,539 citations

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol

1999 • 1,456 citations

The trp ion channel family

2001 • 1,108 citations

Ion Channels and Their Functional Role in Vascular Endothelium

2001 • 850 citations

The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α ₁ -Adrenoceptor–Activated Ca ²⁺ -Permeable Cation Channel

2001 • 596 citations

Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains

1995 • 480 citations

STUDIES ON INFLAMMATION. III. GROWING CAPILLARIES: THEIR STRUCTURE AND PERMEABILITY.

1963 • 430 citations

Impairment of Store-Operated Ca ²⁺ Entry in TRPC4 ^−/− Mice Interferes With Increase in Lung Microvascular Permeability

2002 • 363 citations

Activation of a TRPC3-Dependent Cation Current through the Neurotrophin BDNF

1999 • 343 citations

Tumor-secreted vascular permeability factor increases cytosolic Ca2+ and von Willebrand factor release in human endothelial cells.

1991 • 325 citations

The myosin swinging cross-bridge model

2001 • 314 citations

Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl- channels in Xenopus oocytes.

1990 • 309 citations

Studies on inflammation

1963 • 306 citations

VEGF induces NO-dependent hyperpermeability in coronary venules

1996 • 247 citations

TRPC6 is a candidate channel involved in receptor-stimulated cation currents in A7r5 smooth muscle cells

2002 • 232 citations

Pathways of Macromolecular Extravasation Across Microvascular Endothelium in Response to VPF/VEGF and Other Vasoactive Mediators

1999 • 180 citations

Vascular endothelial growth factor increases hydraulic conductivity of isolated perfused microvessels

1996 • 167 citations

A DEVELOPMENT OF THE LANDIS TECHNIQUE FOR MEASURING THE FILTRATION COEFFICIENT OF INDIVIDUAL CAPILLARIES IN THE FROG MESENTERY

1974 • 166 citations

Potentiation of large conductance KCa channels by niflumic, flufenamic, and mefenamic acids

1994 • 152 citations

Inhibition of Gap Junction Hemichannels by Chloride Channel Blockers

2002 • 151 citations

Vascular endothelial growth factor increases microvascular permeability via a Ca(2+)-dependent pathway

1997 • 150 citations

Expression of Functional Receptor-coupled TRPC3 Channels in DT40 Triple Receptor InsP3 knockout Cells

2001 • 144 citations

A diacylglycerol-activated Ca2+ channel in PC12 cells (an adrenal chromaffin cell line) correlates with expression of the TRP-6 (transient receptor potential) protein

2001 • 95 citations

Vascular permeability factor/vascular endothelial growth factor-mediated signaling in mouse mesentery vascular endothelium.

1998 • 94 citations

ZM323881, a Novel Inhibitor of Vascular Endothelial Growth Factor‐Receptor‐2 Tyrosine Kinase Activity

2002 • 86 citations

Non‐specificity of chloride channel blockers in rat cerebral arteries: block of the L‐type calcium channel

1998 • 84 citations

Openings Through Endothelial Cells Associated with Increased Microvascular Permeability

1999 • 79 citations

Differential actions of cAMP on endothelial [Ca2+]i and permeability in microvessels exposed to ATP

1993 • 69 citations

Ca2+ entry through conductive pathway modulates receptor-mediated increase in microvessel permeability

1996 • 63 citations

Measurement of cytoplasmic calcium in single microvessels with increased permeability

1990 • 60 citations

Two Functional Forms of Vascular Endothelial Growth Factor Receptor-2/Flk-1 mRNA Are Expressed in Normal Rat Retina

1998 • 58 citations

VEGF and ATP act by different mechanisms to increase microvascular permeability and endothelial [Ca²⁺]_i

2000 • 50 citations

Differential Effects of Vascular Endothelial Growth Factor-C and Placental Growth Factor-1 on the Hydraulic Conductivity of Frog Mesenteric Capillaries

2001 • 49 citations

Openings Through Endothelial Cells Associated with Increased Microvascular Permeability

1999 • 44 citations

In vivo mechanisms of vascular endothelial growth factor‐mediated increased hydraulic conductivity of Rana capillaries

2001 • 37 citations

Mechanisms of Heterogeneous Endothelial Cytoplasmic Calcium Increases in Venular Microvessels

2002 • 13 citations

Seasonal variations of capillary hydraulic conductivity and volume status

1995 • 13 citations