Initiation Codon Scanthrough versus Termination Codon Readthrough Demonstrates Strong Potential for Major Histocompatibility Complex Class I–restricted Cryptic Epitope Expression

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

1987 • 1,189 citations

How do eucaryotic ribosomes select initiation regions in messenger RNA?

1978 • 830 citations

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

1985 • 669 citations

ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX

1996 • 613 citations

Effects of Intercistronic Length on the Efficiency of Reinitiation by Eucaryotic Ribosomes

1987 • 540 citations

Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

1985 • 526 citations

Context Effects and Inefficient Initiation at Non-AUG Codons in Eucaryotic Cell-Free Translation Systems

1989 • 471 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

Cell Biology of Antigen Processing and Presentation to Major Histocompatibility Complex Class I Molecule-Restricted T Lymphocytes

1992 • 373 citations

Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

1991 • 336 citations

The Efficiency of Translation Termination is Determined by a Synergistic Interplay Between Upstream and Downstream Sequences inSaccharomyces cerevisiae

1995 • 303 citations

Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen.

1996 • 261 citations

Adherence to the first-AUG rule when a second AUG codon follows closely upon the first.

1995 • 254 citations

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

1991 • 243 citations

A peptide recognized by human cytolytic T lymphocytes on HLA-A2 melanomas is encoded by an intron sequence of the N-acetylglucosaminyltransferase V gene.

1996 • 235 citations

Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells.

1993 • 185 citations

Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes.

1992 • 184 citations

Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance

1995 • 178 citations

Regulation of Protein Synthesis in Virus-Infected Animal Cells

1986 • 177 citations

Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes

1992 • 155 citations

A Consideration of Alternative Models for the Initiation of Translation in Eukaryotes

1992 • 137 citations

Recognition of pre-processed endogenous antigen by class I but not class II MHC-restricted T cells

1989 • 113 citations

MHC class I-associated peptides produced from endogenous gene products with vastly different efficiencies.

1997 • 110 citations

Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames.

1996 • 100 citations

Identification of a unique antigen peptide pRL1 on BALB/c RL male 1 leukemia recognized by cytotoxic T lymphocytes and its relation to the Akt oncogene.

1994 • 95 citations

Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein.

1997 • 93 citations

Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family.

1994 • 88 citations

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

1995 • 81 citations

alpha-Thalassaemia associated with the deletion of two nucleotides at position -2 and -3 preceding the AUG codon.

1985 • 77 citations

Antigen-Specific T-Cell Receptors and Their Reactions with Complexes Formed by Peptides with Major Histocompatibility Complex Proteins

1996 • 75 citations

A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells.

1995 • 70 citations

Presentation of viral antigen to class I major histocompatibility complex-restricted cytotoxic T lymphocyte. Recognition of an immunodominant influenza hemagglutinin site by cytotoxic T lymphocyte is independent of the position of the site in the hemagglutinin translation product.

1991 • 58 citations

The first and third uORFs in RSV leader RNA are efficiently translated: implications for translational regulation and viral RNA packaging

1995 • 49 citations

A frameshift mutation at the NH2 terminus of the nucleoprotein gene does not affect generation of cytotoxic T lymphocyte epitopes.

1991 • 46 citations

Cytotoxic T Cell Recognition of the SV40 Tumor Antigen: A Note of Caution

1988 • 6 citations