A rare cryptic translation product is presented by Kb major histocompatibility complex class I molecule to alloreactive T cells.

The scanning model for translation: an update.

1989 • 3,525 citations

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1994 • 2,480 citations

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

1991 • 2,447 citations

Structural features in eukaryotic mRNAs that modulate the initiation of translation.

1991 • 1,849 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

The somatic generation of immune recognition

1971 • 974 citations

Identification of self peptides bound to purified HLA-B27

1991 • 844 citations

Identification of a Peptide Recognized by Five Melanoma-Specific Human Cytotoxic T Cell Lines

1994 • 841 citations

Peptides Naturally Presented by MHC Class I Molecules

1993 • 803 citations

Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

1990 • 689 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Exact prediction of a natural T cell epitope

1991 • 455 citations

Cellular peptide composition governed by major histocompatibility complex class I molecules

1990 • 438 citations

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens.

1992 • 407 citations

The Molecular Basis of Allorecognition

1993 • 398 citations

Structure of Peptides Associated with Class I and Class II MHC Molecules

1994 • 381 citations

LacZ inducible, antigen/MHC-specific T cell hybrids

1994 • 377 citations

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule

1992 • 344 citations

Selectivity of MHC-encoded peptide transporters from human, mouse and rat

1994 • 339 citations

A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein

1992 • 286 citations

Murine Major Histocompatibility Complex Class-I Mutants: Molecular Analysis and Structure-Function Implications

1986 • 286 citations

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1994 • 275 citations

Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast.

1991 • 266 citations

CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma

1994 • 254 citations

On the nature of peptides involved in T cell alloreactivity.

1991 • 220 citations

Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator.

1994 • 207 citations

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene.

1991 • 191 citations

Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells.

1993 • 185 citations

Peptide-dependent recognition of H–2Kb by alloreactive cytotoxic T lymphocytes

1989 • 168 citations

Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses.

1995 • 148 citations

Alloreactive T cells discriminate among a diverse set of endogenous peptides.

1991 • 136 citations

In vitro peptide binding to soluble empty class I major histocompatibility complex molecules isolated from transfected Drosophila melanogaster cells.

1992 • 134 citations

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone.

1993 • 129 citations

Direct identification of an endogenous peptide recognized by multiple HLA-A2.1-specific cytotoxic T cells.

1993 • 128 citations

Eukaryotic expression vectors for the analysis of mutant proteins

1989 • 126 citations

T cell-recognized antigenic peptides derived from the cellular genome are not protein degradation products but can be generated directly by transcription and translation of short subgenic regions. A hypothesis

1989 • 121 citations

Selecting T Cell Receptors with High Affinity for Self-MHC by Decreasing the Contribution of CD8

1992 • 98 citations

Substrate specificity of allelic variants of the TAP peptide transporter

1994 • 95 citations

Identification of a unique antigen peptide pRL1 on BALB/c RL male 1 leukemia recognized by cytotoxic T lymphocytes and its relation to the Akt oncogene.

1994 • 95 citations

Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune response gene defects.

1985 • 74 citations

Major histocompatibility complex class I allele‐specific peptide libraries: Identification of peptides that mimic an H‐Y T cell epitope

1994 • 49 citations

Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation.

1994 • 48 citations

Major Histocompatibility Class I Molecules Can Present Cryptic Translation Products to T-cells

1995 • 48 citations

A frameshift mutation at the NH2 terminus of the nucleoprotein gene does not affect generation of cytotoxic T lymphocyte epitopes.

1991 • 46 citations

The role of MHC class I molecules in the generation of endogenous peptide/MHC complexes.

1995 • 41 citations

Genes Coding for T-cell-defined Tum Transplantation Antigens: Point Mutations, Antigenic Peptides, and Subgenic Expression

1989 • 40 citations

The peptide p2Ca is immunodominant in allorecognition of Ld by beta chain variable region V beta 8+ but not V beta 8- strains.

1994 • 35 citations

Both Human and Mouse Cells Expressing H-2Kb and Ovalbumin Process the Same Peptide, SIINFEKL

1993 • 27 citations

Single T cell probes for antigen/MHC expression

1995 • 9 citations