Animal Models of PD

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

2000 • 3,559 citations

A Drosophila model of Parkinson's disease

2000 • 2,062 citations

Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

2000 • 1,729 citations

Alpha-synuclein and neurodegenerative diseases

2001 • 1,339 citations

Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease

2002 • 1,220 citations

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

2001 • 1,218 citations

Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

2002 • 1,152 citations

Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53 → Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice

2002 • 760 citations

Dopamine-dependent neurotoxicity of α-synuclein: A mechanism for selective neurodegeneration in Parkinson disease

2002 • 722 citations

The Herbicide Paraquat Causes Up-regulation and Aggregation of α-Synuclein in Mice

2002 • 644 citations

Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.

2002 • 642 citations

Experimental models of Parkinson's disease

2001 • 617 citations

Parkinson-Like Neurodegeneration Induced by Targeted Overexpression of α-Synuclein in the Nigrostriatal System

2002 • 577 citations

β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

2001 • 573 citations

Prospects for new restorative and neuroprotective treatments in Parkinson's disease

1999 • 545 citations

Neuropathology in mice expressing human alpha-synuclein.

2000 • 499 citations

The Nigrostriatal Dopaminergic System as a Preferential Target of Repeated Exposures to Combined Paraquat and Maneb: Implications for Parkinson's Disease

2000 • 462 citations

Neuropathology in Mice Expressing Human α-Synuclein

2000 • 456 citations

β-Synuclein Inhibits α-Synuclein Aggregation

2001 • 401 citations

Behavioral and Neurochemical Effects of Wild-Type and Mutated Human α-Synuclein in Transgenic Mice

2002 • 280 citations

Genetics of Parkinson's disease and biochemical studies of implicated gene products

2002 • 119 citations

Advances in genetic models of Parkinson's disease

2001 • 9 citations