Alterations in hepatocyte cytoskeleton caused by redox cycling and alkylating quinones

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. A study of the implications of oxidative stress in intact cells.

1982 • 893 citations

Actin polymerization and its regulation by proteins from nonmuscle cells.

1982 • 739 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

Blebbing, free Ca2+ and mitochondrial membrane potential preceding cell death in hepatocytes

1987 • 533 citations

Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes

1984 • 411 citations

Menadione-induced cytotoxicity is associated with protein thiol oxidation and alteration in intracellular Ca2+ homeostasis

1984 • 376 citations

Redox cycling and sulphydryl arylation; Their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes

1988 • 296 citations

Free radicals in molecular biology, aging, and disease

1985 • 271 citations

Altered thiol and calcium homeostasis in oxidative hepatocellular injury

1985 • 249 citations

Cystamine induces toxicity in hepatocytes through the elevation of cytosolic Ca2+ and the stimulation of a nonlysosomal proteolytic system.

1986 • 249 citations

Oxidation of glutathione during hydroperoxide metabolism

1984 • 243 citations

Cell surface changes and enzyme release during hypoxia and reoxygenation in the isolated, perfused rat liver.

1983 • 213 citations

Cytoskeletal and morphologic impact of cellular oxidant injury.

1986 • 190 citations

Unpolymerized actin in fibroblasts and brain

1976 • 186 citations

Inhibition of hepatocyte plasma membrane Ca²⁺‐ATPase activity by menadione metabolism and its restoration by thiols

1985 • 168 citations

Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin

1988 • 168 citations

Quinone toxicity in hepatocytes without oxidative stress

1986 • 166 citations

Enzymic basis for the Ca²⁺ion-induced crosslinking of membrane proteins in intact human erythrocytes

1978 • 160 citations

The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro

1984 • 147 citations

Actin microfilaments, cell shape, and secretory processes in isolated rat hepatocytes. Effect of phalloidin and cytochalasin D.

1979 • 136 citations

Interaction of menadione (2-methyl-1,4-naphthoquinone) with glutathione

1985 • 129 citations

Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes.

1975 • 127 citations

The effect of mild diamide oxidation on the structure and function of human erythrocyte spectrin.

1986 • 94 citations

Protein 4.1 in sickle erythrocytes. Evidence for oxidative damage.

1987 • 76 citations

Electron Microscopy of Isolated Rat Hepatocytes before and after Treatment with Phalloidin

1973 • 57 citations

Cytochalasin B disrupts the association of filamentous web and plasma membrane in hepatocytes

1981 • 41 citations

Hepatic cellular injury following lethal Escherichia coli bacteremia in rats.

1982 • 34 citations

Disulfide-linked and transglutaminase-catalyzed protein assemblies in platelets

1985 • 17 citations

Peripheral cytoplasmic shedding around hepatocytes — Apocrine secretion, pathological cell reaction or preparation artifact?

1980 • 14 citations