Controlled Release of Drug Model from N-(2-Hydroxypropyl)-methacrylamide Copolymers

Lysosomotropic agents

1974 • 1,887 citations

Structure and properties of pharmacologically active polymers

1975 • 1,069 citations

Physical and Chemical Studies on Ceruloplasmin

1968 • 468 citations

Soluble synthetic polymers as potential drug carriers

1984 • 308 citations

Polymers containing enzymatically degradable bonds, 8. Degradation of oligopeptide sequences in N‐(2‐hydroxypropyl)methacrylamide copolymers by bovine spleen cathepsin B

1983 • 259 citations

Aminolyses of monomeric and polymeric 4‐nitrophenyl esters of N‐methacryloylamino acids

1977 • 202 citations

Polymers containing enzymatically degradable bonds, 7. Design of oligopeptide side‐chains in poly[N‐(2‐hydroxypropyl)methacrylamide] copolymers to promote efficient degradation by lysosomal enzymes

1983 • 192 citations

Carbohydrate Recognition Systems for Receptor-Mediated Pinocytosis

1980 • 184 citations

Controlled biodegradability of polymers — a key to drug delivery systems

1984 • 155 citations

Polymers containing enzymatically degradable bonds, 1. Chymotrypsin catalyzed hydrolysis of p‐nitroanilides of phenylalanine and tyrosine attached to side‐chains of copolymers of N‐(2‐hydroxypropyl)methacrylamide

1981 • 141 citations

Stability in rat plasma and serum of lysosomally degradable oligopeptide sequences in N-(2-hydroxypropyl) methacrylamide copolymers

1985 • 138 citations

Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues

1983 • 128 citations

Degradation of side-chains of N-(2-hydroxypropyl)methacrylamide copolymers by lysosomal thiol-proteinases

1982 • 102 citations

Reactive copolymers of N‐(2‐hydroxypropyl)methacrylamide with N‐methacryloylated derivatives of <scp>L</scp>‐leucine and <scp>L</scp>‐phenylalanine, 1. Preparation, characterization, and reactions with diamines

1977 • 86 citations

Tyrosinamide residues enhance pinocytic capture of N-(2-hydroxypropyl)methacrylamide copolymers

1984 • 78 citations

Effect of molecular size of 125I-labelled poly(vinylpyrrolidone) on its pinocytosis by rat visceral yolk sacs and rat peritoneal macrophages

1981 • 75 citations

Immunogenicity of N-(2-hydroxypropyl)-methacrylamide copolymers—Potential hapten or drug carriers

1983 • 74 citations

Polymers containing enzymatically degradable bonds V. Hydrophilic polymers degradable by papain

1980 • 65 citations

BIODEGRADATION OF POLYMERS FOR BIOMEDICAL USE

1982 • 62 citations

Effect of the chemical structure of N- (2- hydroxypropyl) methacrylajnide copolymers on their ability to induce antibody formation in inbred strains of mice

1984 • 60 citations

Polymers containing enzymatically degradable bonds, 3. Poly[N‐(2‐hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by trypsin

1981 • 58 citations

Polymers containing enzymatically degradable bonds, 2. Poly[N‐(2‐hydroxypropyl)methacrylamide] chains connected by oligopeptide sequences cleavable by chymotrypsin

1981 • 57 citations

Mechanism of polycation stimulation of pinocytosis

1979 • 39 citations

Adsorptive and passive pinocytic uptake

1980 • 39 citations

Pinocytosis of polyα,β-(N-2-hydroxyethyl))-DL-aspartamide and a tyramine derivative by rat visceral yolk sacs cultured in vitro

1982 • 37 citations

Receptor mediated targeting of drugs

1986 • 35 citations

Reactive copolymers of N‐(2‐hydroxypropyl) methacrylamide with N‐methacryloylated derivatives of l‐leucine and l‐phenylalanine. II. Reaction with the polymeric amine and stability of cross‐links towards chymotrypsin in vitro

1979 • 34 citations

Development of N-(2-Hydroxypropyl)Methacrylamide Copolymers as Carriers of Therapeutic Agents

1983 • 24 citations

Targeting of Antitumour and Antiprotozoal Drugs by Covalent Linkage to Protein Carriers

1982 • 17 citations

DNA, Liposomes, and Proteins as Carriers for Antitumoral Drugs

1980 • 13 citations

Soluble synthetic polymers as targetable agents for intracellular drug release

1983 • 8 citations

Antibodies and Dextran as Anti-Tumour Drug Carriers

1982 • 5 citations