Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

Naturally occurring antibodies devoid of light chains

1993 • 2,872 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

Making Antibodies by Phage Display Technology

1994 • 1,516 citations

Single-Chain Antigen-Binding Proteins

1988 • 1,450 citations

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

1985 • 1,241 citations

Three-Dimensional Structure of an Antigen-Antibody Complex at 2.8 Å Resolution

1986 • 1,173 citations

Conformations of immunoglobulin hypervariable regions

1989 • 1,165 citations

Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

1991 • 1,014 citations

Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

1989 • 989 citations

Assembly of a Functional Immunoglobulin F _v Fragment in Escherichia coli

1988 • 973 citations

Man-made antibodies

1991 • 935 citations

Anatomy of the antibody molecule

1994 • 868 citations

ANTIBODY-ANTIGEN COMPLEXES

1990 • 853 citations

The outline structure of the T-cell alpha beta receptor.

1988 • 625 citations

The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops

1992 • 616 citations

Three-dimensional structure of an antibody-antigen complex.

1987 • 615 citations

Interactions of protein antigens with antibodies.

1996 • 543 citations

Bound water molecules and conformational stabilization help mediate an antigen-antibody association.

1994 • 471 citations

A comparison of strategies to stabilize immunoglobulin Fv-fragments

1990 • 469 citations

Structure of an antibody-antigen complex: crystal structure of the HyHEL-10 Fab-lysozyme complex.

1989 • 456 citations

Sequence and structure of V_H domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

1994 • 449 citations

Structural repertoire of the human VH segments

1992 • 396 citations

Crystal orientation and X-ray pattern prediction routines for area-detector diffractometer systems in macromolecular crystallography

1987 • 396 citations

Domain association in immunoglobulin molecules

1985 • 389 citations

Length distribution of CDRH3 in antibodies

1993 • 277 citations

Crystal Structure of the Principal Neutralization Site of HIV-1

1994 • 245 citations

Framework residue 71 is a major determinant of the position and conformation of the second hypervariable region in the VH domains of immunoglobulins

1990 • 238 citations

Major antigen-induced domain rearrangements in an antibody

1993 • 206 citations

Structural features of the reactions between antibodies and protein antigens

1995 • 205 citations

Immunoglobulin VH clan and family identity predicts variable domain structure and may influence antigen binding.

1992 • 178 citations

Molecular basis of antigen mimicry by an anti-idiotope

1995 • 161 citations

‘Camelising’ human antibody fragments: NMR studies on VH domains

1994 • 149 citations

Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1

1994 • 149 citations

Antibody VH Domains as Small Recognition Units

1995 • 137 citations

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

1993 • 132 citations

Bacterial expression of immunoglobulin fragments

1993 • 132 citations

Antibody-antigen interactions

1994 • 128 citations

Crystal Structure of a Cross-reaction Complex between Fab F9.13.7 and Guinea Fowl Lysozyme

1995 • 84 citations

Protein antigenicity: A thermodynamic approach

1991 • 78 citations

Three-dimensional structure of an Fv from a human IgM immunoglobulin

1992 • 76 citations

Making Antibodies by Phage Display Technology

1994 • 72 citations

Fungi for all

1988 • 67 citations

Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3

1994 • 57 citations

Structural conservation of hypervariable regions in immunoglobulins evolution

1994 • 53 citations

Rearrangement of the Former VL Interface in the Solution Structure of a Camelised, Single Antibody VH Domain

1996 • 53 citations

The minimal antigen-binding fragment of antibodies—Fv fragment

1991 • 49 citations

Refined Structure of the Monoclonal Antibody HyHEL-5 with its Antigen Hen Egg-White Lysozyme

1996 • 42 citations

Structural Patterns at Residue Positions 9, 18, 67 and 82 in the VH Framework Regions of Human and Murine Immunoglobulins

1993 • 39 citations

X-ray structure of a monoclinic form of hen egg-white lysozyme crystallized at 313 K. Comparison of two independent molecules

1994 • 31 citations

Antibody-Antigen Complexes

1990 • 29 citations

Antibody engineering

1995 • 12 citations