Back to search

Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells.

Data up to Jan 2025

Published1995
Citations221
References74

Total Citations Per Year

Abstract

References (74)

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans

1992 • 1,095 citations

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

1989 • 961 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

1990 • 753 citations

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

1987 • 752 citations

Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.

1990 • 695 citations

Molecular cloning of syndecan, an integral membrane proteoglycan.

1989 • 505 citations

Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization.

1982 • 477 citations

10 nm filaments in normal and transformed cells

1978 • 449 citations

Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity

1990 • 444 citations

Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns.

1994 • 413 citations

Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.

1989 • 411 citations

Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.

1994 • 364 citations

Cell surface proteoglycan binds mouse mammary epithelial cells to fibronectin and behaves as a receptor for interstitial matrix

1988 • 345 citations

Novel function for beta 1 integrins in keratinocyte cell-cell interactions.

1990 • 338 citations

Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody

1984 • 318 citations

Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.

1986 • 314 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells. Cell surface proteoglycan as a receptor for interstitial collagens.

1985 • 284 citations

Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture.

1982 • 282 citations

Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse

1989 • 277 citations

Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.

1990 • 274 citations

Immunocytochemistry of cell surface heparan sulfate proteoglycan in mouse tissues. A light and electron microscopic study.

1987 • 252 citations

Catenins as mediators of the cytoplasmic functions of cadherins

1993 • 249 citations

Induced expression of syndecan in healing wounds.

1991 • 249 citations

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

1992 • 236 citations

Heparan sulfate-mediated binding of epithelial cell surface proteoglycan to thrombospondin

1989 • 222 citations

Epithelial Cell Cultures From Normal Glandular Tissue of Mice 2

1974 • 214 citations

Syndecan from embryonic tooth mesenchyme binds tenascin.

1991 • 214 citations

Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.

1993 • 210 citations

The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak

1993 • 209 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

1985 • 185 citations

Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis

1988 • 181 citations

N-linked oligosaccharides are not involved in the function of a cell-cell binding glycoprotein E-cadherin.

1986 • 177 citations

Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain.

1987 • 170 citations

Core protein structure and sequence determine the site and presence of heparan sulfate and chondroitin sulfate on syndecan-1.

1994 • 169 citations

Syndecan expression regulates cell morphology and growth of mouse mammary epithelial tumor cells.

1992 • 165 citations

Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation.

1979 • 164 citations

Integrin heterodimer and receptor complexity in avian and mammalian cells.

1989 • 156 citations

The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells

1992 • 138 citations

Growth factors induce 3T3 cells to express bFGF-binding syndecan.

1992 • 138 citations

Cytoskeleton and thyroglobulin expression change during transformation of thyroid epithelium to mesenchyme-like cells*

1988 • 138 citations

Cytodifferentiation and tissue phenotype change during transformation of embryonic lens epithelium to mesenchyme-like cells in vitro

1986 • 130 citations

[10] The determination of the exposed proteins on membranes by the use of lactoperoxidase

1974 • 123 citations

Transient expression of a cell surface heparan sulfate proteoglycan (syndecan) during limb development

1990 • 119 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells. Basal extracellular proteoglycan binds specifically to native type I collagen fibrils.

1984 • 118 citations

Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo

1991 • 115 citations

Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts.

1992 • 109 citations

Syndecan-1, a Cell-Surface Proteoglycan, Changes in Size and Abundance when Keratinocytes Stratify

1992 • 106 citations

Remodelling of the Basement Membrane: Morphogenesis and Maturation

1984 • 101 citations

Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis: I. Lung epithelial morphogenesis

1989 • 101 citations

Type I collagen gel induces Madin-Darby canine kidney cells to become fusiform in shape and lose apical-basal polarity.

1989 • 100 citations

Developmental expression of syndecan, an integral membrane proteoglycan, correlates with cell differentiation

1991 • 99 citations

Syndecan-1 expressed in Schwann cells causes morphological transformation and cytoskeletal reorganization and associates with actin during cell spreading

1994 • 95 citations

Steroid-induced epithelial-fibroblastic conversion associated with syndecan suppression in S115 mouse mammary tumor cells.

1991 • 82 citations

Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells

1993 • 79 citations

Collagen-induced morphogenesis and expression of the alpha 2-integrin subunit is inhibited in c-erbB2-transfected human mammary epithelial cells.

1993 • 74 citations

Expression of syndecan-1 is induced by differentiation and suppressed by malignant transformation of human keratinocytes.

1994 • 73 citations

Possible Regulation of FGF Activity by Syndecan, an Integral Membrane Heparan Sulfate Proteoglycana

1991 • 65 citations

Inhibition of expression of protein kinase C alpha by antisense cDNA inhibits phorbol ester-mediated arachidonate release

1993 • 59 citations

Regulation of pp60c-src synthesis by inducible RNA complementary to c-src mRNA in polyomavirus-transformed rat cells.

1986 • 49 citations

Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line.

1990 • 44 citations

Heparin and heparan sulfate delimit nephron formation in fetal metanephric kidneys

1990 • 41 citations

Basal Lamina Formation by Normal and Transformed Mouse Mammary Epithelial Cells Duplicated in Vitro<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>

1981 • 38 citations

Morphological and biological modifications induced in a rat pancreatic acinar cancer cell line (AR4-2J) by unscheduled expression of basic fibroblast growth factors.

1993 • 25 citations

Chromosome mapping of the murine syndecan gene

1991 • 18 citations

Characterization of differentiation antigens of the mouse mammary epithelial cell (MME antigens) carried on the mouse milk fat globule

1978 • 18 citations

Regulation of pp60c-src Synthesis by Inducible RNA Complementary to c-src mRNA in Polyomavirus-Transformed Rat Cells

1986 • 17 citations

Reduced expression of AP27 protein, the product of a growth factor-repressible gene, is associated with diminished adipocyte differentiation.

1992 • 14 citations

Inhibition of kidney tubule induction by charged polymers

1978 • 12 citations

Matrix receptors and development.

1992 • 4 citations

Cited By (0)

No citing papers found in database

Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent… (1995) – Molecular Biology of the Cell | Metascience Observatory Explorer