Loss of cell surface syndecan-1 causes epithelia to transform into anchorage-independent mesenchyme-like cells.
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References (74)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
1970 • 253,849 citations
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 • 47,043 citations
Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role
1991 • 1,686 citations
The cadherins: cell-cell adhesion molecules controlling animal morphogenesis
1988 • 1,626 citations
Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans
1992 • 1,095 citations
Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.
1989 • 961 citations
A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.
1987 • 767 citations
Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.
1990 • 753 citations
Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA
1987 • 752 citations
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells.
1990 • 695 citations
Molecular cloning of syndecan, an integral membrane proteoglycan.
1989 • 505 citations
Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization.
1982 • 477 citations
10 nm filaments in normal and transformed cells
1978 • 449 citations
Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity
1990 • 444 citations
Members of the syndecan family of heparan sulfate proteoglycans are expressed in distinct cell-, tissue-, and development-specific patterns.
1994 • 413 citations
Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.
1989 • 411 citations
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds.
1994 • 364 citations
Cell surface proteoglycan binds mouse mammary epithelial cells to fibronectin and behaves as a receptor for interstitial matrix
1988 • 345 citations
Novel function for beta 1 integrins in keratinocyte cell-cell interactions.
1990 • 338 citations
Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody
1984 • 318 citations
Cell surface proteoglycan associates with the cytoskeleton at the basolateral cell surface of mouse mammary epithelial cells.
1986 • 314 citations
Heparan sulfate proteoglycans from mouse mammary epithelial cells. Cell surface proteoglycan as a receptor for interstitial collagens.
1985 • 284 citations
Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture.
1982 • 282 citations
Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse
1989 • 277 citations
Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor.
1990 • 274 citations
Immunocytochemistry of cell surface heparan sulfate proteoglycan in mouse tissues. A light and electron microscopic study.
1987 • 252 citations
Catenins as mediators of the cytoplasmic functions of cadherins
1993 • 249 citations
Induced expression of syndecan in healing wounds.
1991 • 249 citations
Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion
1992 • 236 citations
Heparan sulfate-mediated binding of epithelial cell surface proteoglycan to thrombospondin
1989 • 222 citations
Epithelial Cell Cultures From Normal Glandular Tissue of Mice 2
1974 • 214 citations
Syndecan from embryonic tooth mesenchyme binds tenascin.
1991 • 214 citations
Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion.
1993 • 210 citations
The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak
1993 • 209 citations
Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.
1985 • 185 citations
Cell surface proteoglycan expression correlates with epithelial-mesenchymal interaction during tooth morphogenesis
1988 • 181 citations
N-linked oligosaccharides are not involved in the function of a cell-cell binding glycoprotein E-cadherin.
1986 • 177 citations
Cell surface proteoglycan of mouse mammary epithelial cells is shed by cleavage of its matrix-binding ectodomain from its membrane-associated domain.
1987 • 170 citations
Core protein structure and sequence determine the site and presence of heparan sulfate and chondroitin sulfate on syndecan-1.
1994 • 169 citations
Syndecan expression regulates cell morphology and growth of mouse mammary epithelial tumor cells.
1992 • 165 citations
Collagen reduces glycosaminoglycan degradation by cultured mammary epithelial cells: possible mechanism for basal lamina formation.
1979 • 164 citations
Integrin heterodimer and receptor complexity in avian and mammalian cells.
1989 • 156 citations
The Mouse Wnt-1 Gene Can Act Via a Paracrine Mechanism in Transformation of Mammary Epithelial Cells
1992 • 138 citations
Growth factors induce 3T3 cells to express bFGF-binding syndecan.
1992 • 138 citations
Cytoskeleton and thyroglobulin expression change during transformation of thyroid epithelium to mesenchyme-like cells*
1988 • 138 citations
Cytodifferentiation and tissue phenotype change during transformation of embryonic lens epithelium to mesenchyme-like cells in vitro
1986 • 130 citations
[10] The determination of the exposed proteins on membranes by the use of lactoperoxidase
1974 • 123 citations
Transient expression of a cell surface heparan sulfate proteoglycan (syndecan) during limb development
1990 • 119 citations
Heparan sulfate proteoglycans from mouse mammary epithelial cells. Basal extracellular proteoglycan binds specifically to native type I collagen fibrils.
1984 • 118 citations
Expression of syndecan, a putative low affinity fibroblast growth factor receptor, in the early mouse embryo
1991 • 115 citations
Differential expression of cell surface heparan sulfate proteoglycans in human mammary epithelial cells and lung fibroblasts.
1992 • 109 citations
Syndecan-1, a Cell-Surface Proteoglycan, Changes in Size and Abundance when Keratinocytes Stratify
1992 • 106 citations
Remodelling of the Basement Membrane: Morphogenesis and Maturation
1984 • 101 citations
Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis: I. Lung epithelial morphogenesis
1989 • 101 citations
Type I collagen gel induces Madin-Darby canine kidney cells to become fusiform in shape and lose apical-basal polarity.
1989 • 100 citations
Developmental expression of syndecan, an integral membrane proteoglycan, correlates with cell differentiation
1991 • 99 citations
Syndecan-1 expressed in Schwann cells causes morphological transformation and cytoskeletal reorganization and associates with actin during cell spreading
1994 • 95 citations
Steroid-induced epithelial-fibroblastic conversion associated with syndecan suppression in S115 mouse mammary tumor cells.
1991 • 82 citations
Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells
1993 • 79 citations
Collagen-induced morphogenesis and expression of the alpha 2-integrin subunit is inhibited in c-erbB2-transfected human mammary epithelial cells.
1993 • 74 citations
Expression of syndecan-1 is induced by differentiation and suppressed by malignant transformation of human keratinocytes.
1994 • 73 citations
Possible Regulation of FGF Activity by Syndecan, an Integral Membrane Heparan Sulfate Proteoglycana
1991 • 65 citations
Inhibition of expression of protein kinase C alpha by antisense cDNA inhibits phorbol ester-mediated arachidonate release
1993 • 59 citations
Regulation of pp60c-src synthesis by inducible RNA complementary to c-src mRNA in polyomavirus-transformed rat cells.
1986 • 49 citations
Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line.
1990 • 44 citations
Heparin and heparan sulfate delimit nephron formation in fetal metanephric kidneys
1990 • 41 citations
Basal Lamina Formation by Normal and Transformed Mouse Mammary Epithelial Cells Duplicated in Vitro<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>
1981 • 38 citations
Morphological and biological modifications induced in a rat pancreatic acinar cancer cell line (AR4-2J) by unscheduled expression of basic fibroblast growth factors.
1993 • 25 citations
Chromosome mapping of the murine syndecan gene
1991 • 18 citations
Characterization of differentiation antigens of the mouse mammary epithelial cell (MME antigens) carried on the mouse milk fat globule
1978 • 18 citations
Regulation of pp60c-src Synthesis by Inducible RNA Complementary to c-src mRNA in Polyomavirus-Transformed Rat Cells
1986 • 17 citations
Reduced expression of AP27 protein, the product of a growth factor-repressible gene, is associated with diminished adipocyte differentiation.
1992 • 14 citations
Inhibition of kidney tubule induction by charged polymers
1978 • 12 citations
Matrix receptors and development.
1992 • 4 citations
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