Enhancement by Monocytes of Perform Production and Its Gene Expression by Human CD8+ T Cells Stimulated with Interleukin‐2

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

The Regulatory Role of Macrophages in Antigenic Stimulation Part Two: Symbiotic Relationship between Lymphocytes and Macrophages

1981 • 518 citations

Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor.

1981 • 516 citations

Lymphokine-activated killer cells. Analysis of progenitors and effectors.

1986 • 403 citations

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.

1985 • 398 citations

Structure and function of human perforin

1988 • 346 citations

Perforin-Mediated Target Cell Lysis by Cytolytic T Lymphocytes

1990 • 268 citations

The molecular mechanism of lymphocyte-mediated tumor cell lysis

1985 • 183 citations

Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta.

1987 • 172 citations

Synergy of tumor necrosis factor and interleukin 2 in the activation of human cytotoxic lymphocytes: effect of tumor necrosis factor alpha and interleukin 2 in the generation of human lymphokine-activated killer cell cytotoxicity.

1988 • 172 citations

IFN-beta 2/IL-6 augments the activity of human natural killer cells.

1989 • 150 citations

Killing of target cells by lymphocytes: a mechanistic view.

1989 • 134 citations

Purification and characterization of recombinant human interleukin-2 produced in Escherichia coli

1985 • 125 citations

Interleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.

1990 • 106 citations

Interaction of recombinant interferons with recombinant interleukin‐2: Differential effects on natural killer cell activity and interleukin‐2‐activated killer cells

1986 • 101 citations

IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells.

1990 • 77 citations

Synergy of human recombinant interleukin 1 with interleukin 2 in the generation of lymphokine-activated killer cells.

1989 • 74 citations

Inhibition of lymphocyte mediated cytotoxicity by perforin antisense oligonucleotides.

1990 • 73 citations

Differential Effects of Recombinant Interferons , beta, and on Induction of Human Lymphokine (IL-2)-Activated Killer Activity

1988 • 62 citations

Effects of human alveolar macrophages on the induction of lymphokine (IL 2)-activated killer cells.

1987 • 57 citations

Molecular cloning and chromosomal assignment of a human perforin (PFP) gene

1989 • 51 citations

Up‐ and down‐regulation of human lymphokine (IL‐2)‐activated killer cell induction by monocytes, depending on their functional state

1988 • 49 citations

Heterogeneity of human lymphokine (IL‐2)‐activated killer (LAK) precursors and regulation of their LAK induction by blood monocytes

1988 • 42 citations

Interleukin-4 as a potent down-regulator for human alveolar macrophages capable of producing tumour necrosis factor-alpha and interleukin-1

1992 • 41 citations

Functional interactions of IL2 and TNF in the differentiation of LGL into lak effectors

1989 • 33 citations

Interleukin‐4 Downregulates Interleukin‐6 Production by Human Alveolar Macrophages at Protein and mRNA Levels

1991 • 30 citations

Monocyte‐dependent induction of proliferation of human peripheral T cells by recombinant interleukin 2

1986 • 30 citations

Down-regulation by interleukin 4 of activation of human alveolar macrophages to the tumoricidal state.

1991 • 28 citations

Lymphokine-induced cytotoxicity: requirement of two lymphokines for the induction of optimal cytotoxic response.

1985 • 28 citations

Thy-1 -positive dendritic epidermal cells contain a killer protein perforin

1990 • 21 citations

A C9 related channel forming protein in the cytoplasmic granules of human large granular lymphocytes

1985 • 21 citations

Induction of synthesis of the cytolytic C9 (ninth component of complement)-related protein in human peripheral mononuclear cells by monoclonal antibody OKT3 or interleukin 2: correlation with cytotoxicity and lymphocyte phenotype.

1987 • 18 citations

Lymphokine-induced cytotoxicity: characterization of effectors, precursors, and regulatory ancillary cells.

1986 • 17 citations

Combined quantitative cytophotometric method for staining indolyl and sulfhydryl groups and protein.

1983 • 4 citations

Deleted Work

1955 • 0 citations

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