Apoptotic death of lymphocytes in murine acquired immunodeficiency syndrome: Involvement of Fas‐Fas ligand interaction

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1989 • 1,252 citations

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

1991 • 1,223 citations

Lpr and gld: Single Gene Models of Systemic Autoimmunity and Lymphoproliferative Disease

1991 • 1,185 citations

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1991 • 1,090 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

1992 • 510 citations

Effect of bcl-2 on Fas antigen-mediated cell death.

1993 • 442 citations

Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide.

1993 • 410 citations

T‐Cell Responses to Mls and to Bacterial Proteins that Mimic its Behavior^#

1989 • 337 citations

Severe immunodeficiency disease induced by a defective murine leukaemia virus

1989 • 258 citations

Mls — a retrovirus exploits the immune system

1991 • 233 citations

Retrovirus-induced immunodeficiency in the mouse

1992 • 221 citations

Defective virus is associated with induction of murine retrovirus-induced immunodeficiency syndrome.

1989 • 209 citations

A Virus-Encoded "Superantigen" in a Retrovirus-Induced Immunodeficiency Syndrome of Mice

1991 • 198 citations

Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission

1993 • 189 citations

The Mycoplasma arthritidis T-cell mitogen MAM: a model superantigen

1991 • 168 citations

CD4+ T cells are required for development of a murine retrovirus-induced immunodeficiency syndrome (MAIDS).

1988 • 147 citations

Functional T lymphocytes are required for a murine retrovirus-induced immunodeficiency disease (MAIDS).

1987 • 138 citations

Experiment and Discussion on Leukaemogenesis by Cell-free Extracts of Radiation-induced Leukaemia in Mice

1962 • 125 citations

Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice.

1993 • 125 citations

Fatal interactions: fas-induced apoptosis of mature T cells

1994 • 118 citations

Characteristics and contributions of defective, ecotropic, and mink cell focus-inducing viruses involved in a retrovirus-induced immunodeficiency syndrome of mice

1991 • 110 citations

B cells are required for induction of T cell abnormalities in a murine retrovirus-induced immunodeficiency syndrome.

1990 • 106 citations

Immunodeficiency and Clonal Growth of Target Cells Induced by Helper-Free Defective Retrovirus

1989 • 94 citations

Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism.

1994 • 72 citations

CD4 T cells in murine acquired immunodeficiency syndrome: polyclonal progression to anergy.

1992 • 53 citations

Characterization of the gag/fusion protein encoded by the defective Duplan retrovirus inducing murine acquired immunodeficiency syndrome

1990 • 48 citations

Murine AIDS superantigen reactivity of the T cells bearing V beta 5 T cell antigen receptor.

1992 • 33 citations

Increased Fas antigen expression in murine retrovirus‐induced immunodeficiency syndrome, MAIDS

1994 • 28 citations

Preferential expansion and activation of V beta 5+ CD4+ T cells in murine acquired immunodeficiency syndrome.

1993 • 20 citations

Sequence heterogeneity of murine acquired immunodeficiency syndrome virus: the role of endogenous virus

1995 • 13 citations

Interaction between T cells and murine acquired immunodeficiency virus superantigen: effect of second signal on T cell reactivity to the MAIDS virus superantigen

1993 • 6 citations