Clinical significance of serum cytokine patterns during start of fever in patients with neutropenia

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

Interleukin-1 receptor antagonist reduces mortality from endotoxin shock

1990 • 865 citations

Management of Fever in Patients with Cancer and Treatment-Induced Neutropenia

1993 • 850 citations

Increased plasma levels of interleukin-6 in sepsis [see comments]

1989 • 813 citations

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways

1990 • 796 citations

Circulating Interleukin-1 and Tumor Necrosis Factor in Septic Shock and Experimental Endotoxin Fever

1990 • 765 citations

Septic shock: pathogenesis

1991 • 743 citations

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways

1990 • 611 citations

Toward an Epidemiology and Natural History of SIRS (Systemic Inflammatory Response Syndrome)

1992 • 479 citations

From the Infectious Diseases Society of America: Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with Unexplained Fever

1990 • 405 citations

Anticytokine Strategies in the Treatment of the Systemic Inflammatory Response Syndrome

1993 • 397 citations

Septicemia and Shock Syndrome Due to Viridans Streptococci: A Case-Control Study of Predisposing Factors

1992 • 386 citations

Interleukin-10 production during septicaemia

1994 • 365 citations

Plasma Tumor Necrosis Factor in Patients with Septic Shock: Mortality Rate, Incidence of Adult Respiratory Distress Syndrome, and Effects of Methylprednisolone Administration

1990 • 335 citations

Plasma tumor necrosis factor and mortality in critically ill septic patients

1989 • 324 citations

Production of interleukin-1-receptor antagonist during experimental endotoxaemia

1991 • 311 citations

Release of soluble receptors for tumor necrosis factor (TNF) in relation to circulating TNF during experimental endotoxinemia.

1992 • 238 citations

Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease

1992 • 209 citations

Human neutrophils produce high levels of the interleukin 1 receptor antagonist in response to granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.

1992 • 179 citations

Endogenous haemopoietic growth factors in neutropenia and infection

1994 • 178 citations

Release of tumor necrosis factor by human polymorphonuclear leukocytes

1990 • 144 citations

Efficacy of a Monoclonal Antibody Directed against Tumor Necrosis Factor in Protecting Neutropenic Rats from Lethal Infection with Pseudomonas aeruginosa

1990 • 123 citations

Tumor necrosis factor and interleukin-6 in Candida albicans infection in normal and granulocytopenic mice

1992 • 110 citations

Interleukin-6 and Its Relationship to C-Reactive Protein and Fever in Children with Febrile Neutropenia

1992 • 99 citations

Role of Interferon- in Experimental Gram-Negative Sepsis

1992 • 90 citations

Peripheral blood neutrophil production of interleukin-1 receptor antagonist and interleukin-1β

1994 • 84 citations

Bioactive and Inactive Forms of Tumor Necrosis Factor- in Spinal Fluid from Patients with Meningitis

1991 • 64 citations

Cytokine and Acute-Phase Reactant Levels in Serum of Children with Cancer Admitted for Fever and Neutropenia

1992 • 61 citations

Cytokine mediators of septic infections in the normal and granulocytopenic host

1993 • 51 citations

Cytokine response to infection in patients with acute myelogenous leukaemia following intensive chemotherapy

1994 • 51 citations

Monitoring of endotoxin, interleukin‐6 and C‐reactive protein serum concentrations in neutropenic patients with fever

1995 • 51 citations

How gram-positive organisms cause sepsis

1993 • 42 citations

Trimethoprim-Sulfamethoxazole plus Amikacin as First-Line Therapy and Imipenem/Cilastatin as Second Empirical Therapy in Febrile Neutropenic Patients with Hematological Disorders

1992 • 20 citations