Cystic fibrosis hetero–and homozygosity is associated with inhibition of breast cancer growth

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

1992 • 1,230 citations

An Animal Model for Cystic Fibrosis Made by Gene Targeting

1992 • 921 citations

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

1995 • 647 citations

The multidrug resistance (mdr1) gene product functions as an ATP channel.

1993 • 372 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

THE RISK OF CANCER AMONG PATIENTS WITH CYSTIC FIBROSIS

1995 • 296 citations

Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice.

1993 • 125 citations

P2-purinergic receptor agonists inhibit the growth of androgen-independent prostate carcinoma cells.

1992 • 97 citations

MDA-MB-134 breast carcinoma cells overexpress fibroblast growth factor (FGF) receptors and are growth-inhibited by FGF ligands.

1994 • 95 citations

Toward an animal model of cystic fibrosis: targeted interruption of exon 10 of the cystic fibrosis transmembrane regulator gene in embryonic stem cells.

1991 • 90 citations

Anticancer activities of adenine nucleotides in mice are mediated through expansion of erythrocyte ATP pools.

1989 • 82 citations

Growth inhibition of human tumor cells in soft-agar cultures by treatment with low levels of adenosine 5'-triphosphate.

1983 • 76 citations

Transfected MCF-7 cells as a model for breast cancer progression

1994 • 49 citations

Biosynthetic and growth abnormalities are associated with high-level expression of CFTR in heterologous cells

1996 • 41 citations

Mapping of the nu gene using congenic nude strains and in situ hybridization.

1992 • 26 citations

Frequency of carriers of cystic fibrosis gene among patients with myeloid malignancy and melanoma.

1991 • 26 citations

Anticancer activities of adenine nucleotides in tumor bearing hosts

1993 • 26 citations

Effect of Intraperitoneal ATP on Tumor Growth and Bone Marrow Radiation Tolerance

1995 • 12 citations

Localization of the cystic fibrosis transmembrane conductance regulator (<i>Cftr</i>) to mouse chromosome 6

1992 • 4 citations

Raised adenine nucleotide concentrations in erythrocytes of patients with cystic fibrosis

1993 • 4 citations

Tumor growth retardation and pathophysiological effects of adenosine 5′‐triphosphate therapy measured by thallium washout, ³¹P nuclear magnetic resonance, laser doppler flowmetry, and intradermal angiogenesis

1993 • 3 citations