Biomechanical activation of vascular endothelium as a determinant of its functional phenotype

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Flow-mediated endothelial mechanotransduction

1995 • 2,728 citations

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein

1997 • 2,050 citations

The Emerging Concept of Vascular Remodeling

1994 • 1,563 citations

MIPS: a database for genomes and protein sequences

2000 • 1,295 citations

Matrix metalloproteinases: effectors of development and normal physiology

2000 • 1,236 citations

Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent

1986 • 1,106 citations

Laminar Shear Stress

1998 • 1,052 citations

THE CELLULAR AND MOLECULAR RESPONSE OF CARDIAC MYOCYTES TO MECHANICAL STRESS

1997 • 876 citations

Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress.

1996 • 851 citations

Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro.

1986 • 835 citations

Endothelial Dysfunction, Hemodynamic Forces, and Atherogenesis^a

2000 • 828 citations

Hemodynamic forces are complex regulators of endothelial gene expression

1995 • 547 citations

The NF-κB signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation

2000 • 545 citations

Connective Tissue Growth Factor: What's in a Name?

2000 • 483 citations

p53 regulates a G ₂ checkpoint through cyclin B1

1999 • 428 citations

Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype

1999 • 384 citations

Increased endothelial cell turnover in areas of in vivo Evans Blue uptake in the pig aorta

1973 • 377 citations

Biomechanical activation: an emerging paradigm in endothelial adhesion biology.

1997 • 348 citations

Actin Filament Stress Fibers in Vascular Endothelial Cells in Vivo

1983 • 334 citations

SPATIAL RELATIONSHIPS IN EARLY SIGNALING EVENTS OF FLOW-MEDIATED ENDOTHELIAL MECHANOTRANSDUCTION

1997 • 319 citations

Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

1997 • 317 citations

Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity.

2000 • 311 citations

Fluid Flow Rapidly Activates G Proteins in Human Endothelial Cells

1996 • 265 citations

Molecular mechanism of endothelial growth arrest by laminar shear stress

2000 • 255 citations

Laminar Shear Stress Inhibits Vascular Endothelial Cell Proliferation by Inducing Cyclin-Dependent Kinase Inhibitor p21 ^{Sdi1/Cip1/Waf1}

2000 • 251 citations

Fluid Shear Stress Activates Ca ²⁺ Influx Into Human Endothelial Cells via P2X4 Purinoceptors

2000 • 250 citations

Factors influencing the expression of stress fibers in vascular endothelial cells in situ.

1983 • 233 citations

The riddle of morphogenesis: A question of solution chemistry or molecular cell engineering?

1993 • 219 citations

Apparatus for subjecting living cells to fluid shear stress

1982 • 174 citations

Secondary flow and turbulence in a cone-and-plate device

1984 • 170 citations

The molecular bases of restenosis

1997 • 129 citations

The molecular basis of cell cycle and growth control

1999 • 95 citations

Brief Reviews: Hemodynamic Theories of Atherogenesis

1973 • 95 citations

Thioredoxin reductase is the major selenoprotein expressed in human umbilical-vein endothelial cells and is regulated by protein kinase C

1999 • 50 citations

Fluid Mechanics of Arterial Flow

1979 • 46 citations

Flow-Mediated Regulation of G-Protein Expression in Cocultured Vascular Smooth Muscle and Endothelial Cells

1998 • 39 citations