Fluid Flow Rapidly Activates G Proteins in Human Endothelial Cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Flow-mediated endothelial mechanotransduction

1995 • 2,728 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Flow Effects on Prostacyclin Production by Cultured Human Endothelial Cells

1985 • 1,237 citations

Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells

1994 • 520 citations

GTP-binding proteins in membranes and the control of adenylate cyclase activity.

1977 • 456 citations

Vascular Fluid Mechanics, the Arterial Wall, and Atherosclerosis

1992 • 451 citations

Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells

1993 • 386 citations

Shear stress induced stimulation of mammalian cell metabolism

1988 • 370 citations

Fluid shear stress modulates cytosolic free calcium in vascular endothelial cells

1992 • 355 citations

Fluid Shear Stress Stimulates Mitogen-Activated Protein Kinase in Endothelial Cells

1995 • 287 citations

Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells

1994 • 248 citations

Shear stress increases inositol trisphosphate levels in human endothelial cells

1990 • 215 citations

Shear Stress Induces ATP-Independent Transient Nitric Oxide Release From Vascular Endothelial Cells, Measured Directly With a Porphyrinic Microsensor

1995 • 209 citations

Pulsatile and steady flow induces c‐fos expression in human endothelial cells

1993 • 203 citations

Integrating with integrins.

1994 • 189 citations

Flow-induced calcium transients in single endothelial cells: spatial and temporal analysis

1992 • 184 citations

Mechanism of shear-induced prostacyclin production in endothelial cells

1989 • 136 citations

Shear‐induced platelet‐derived growth factor gene expression in human endothelial cells is mediated by protein kinase C

1992 • 134 citations

Flow-related responses of intracellular inositol phosphate levels in cultured aortic endothelial cells.

1993 • 107 citations

Fluid Shear Stress Stimulates Membrane Phospholipid Metabolism in Cultured Human Endothelial Cells

1992 • 93 citations

A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. I. Identification by photolabeling or membrane and ternary complex preparation.

1990 • 91 citations

Transfected m2 muscarinic acetylcholine receptors couple to G alpha i2 and G alpha i3 in Chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathway.

1993 • 86 citations

Flow‐induced prostacyclin production is mediated by a pertussis toxin‐sensitive G protein

1992 • 80 citations

Microaggregate formation in whole blood exposed to shear stress

1978 • 34 citations

Fluid flow increases membrane permeability to merocyanine 540 in human endothelial cells

1994 • 30 citations

Flow- and bradykinin-induced nitric oxide production by endothelial cells is independent of membrane potential

1996 • 20 citations