The renin-angiotensin system and volume overload-induced changes in cardiac collagen and elastin.

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

1990 • 607 citations

Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle.

1989 • 500 citations

Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries.

1991 • 411 citations

Cardioreparative effects of lisinopril in rats with genetic hypertension and left ventricular hypertrophy.

1991 • 329 citations

Reactive and reparative myocardial fibrosis in arterial hypertension in the rat

1992 • 268 citations

Fibrillar collagen and remodeling of dilated canine left ventricle.

1990 • 264 citations

Cardiac hypertrophy and antihypertensive therapy

1977 • 260 citations

Collagen network remodelling and diastolic stiffness of the rat left ventricle with pressure overload hypertrophy

1988 • 243 citations

The growth of the muscular and collagenous parts of the rat heart in various forms of cardiomegaly

1969 • 171 citations

Hemodynamic versus adrenergic control of cat right ventricular hypertrophy.

1985 • 146 citations

Morphometric analysis of collagen network and plasma perfused capillary bed in the myocardium of rats during evolution of cardiac hypertrophy

1986 • 118 citations

The renin-angiotensin system and volume overload-induced cardiac hypertrophy in rats. Effects of angiotensin converting enzyme inhibitor versus angiotensin II receptor blocker.

1993 • 117 citations

Chronic progressive pressure overload of the cat right ventricle.

1981 • 110 citations

Hemodynamic Effects of Direct Angiotensin II Blockade Compared to Converting Enzyme Inhibition in Rat Model of Heart Failure

1991 • 101 citations

Enalapril prevents cardiac fibrosis and arrhythmias in hypertensive rats.

1991 • 101 citations

Effect of age on myocardial adaptation to volume overload in the rat.

1988 • 93 citations

Enalapril suppresses normal accumulation of elastin and collagen in cardiovascular tissues of growing rats

1992 • 70 citations

Effects of arterial vasodilators on cardiac hypertrophy and sympathetic activity in rats.

1988 • 69 citations

Effects of enalapril versus losartan on regression of volume overload-induced cardiac hypertrophy in rats.

1994 • 67 citations

Myocardial Collagen and Mechanics After Preventing Hypertrophy in Hypertensive Rats

1989 • 52 citations

Myocardial collagen in different forms of heart hypertrophy in the rat

1980 • 52 citations

Vasodilating Drugs: Contrasting Haemodynamic Effects

1976 • 51 citations

Functional and morphological characteristics of compensated and decompensated cardiac hypertrophy in dogs with chronic infrarenal aorto-caval fistulas.

1990 • 36 citations

Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats

1985 • 33 citations

Time-Course of Changes in Cardiac Hypertrophy and Pressor Mechanisms in Two-Kidney, One Clip Hypertensive Rats During Treatment with Minoxidil, Enalapril or After Uninephrectomy

1987 • 27 citations

Arterial vasodilation and cardiovascular structural changes in normotensive rats

1991 • 16 citations

Accumulation and Regulation of Elastin in the Rat Uterus

1989 • 15 citations

Arterial vasodilators, cardiac volume load, and cardiac hypertrophy in normotensive rats

1989 • 13 citations

Renin-angiotensin system and minoxidil-induced cardiac hypertrophy in rats

1993 • 13 citations

Automated image analysis of myocardial collagen pattern in pressure and volume overload in rat cardiac hypertrophy.

1986 • 13 citations

Effect of Calcium Antagonists and Other Drugs on the Hypoxia-induced Increase in Rat Right Ventricular Pressure

1989 • 6 citations

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