Deactivation of cultured human liver myofibroblasts by Trans -resveratrol, a grapevine-derived polyphenol

A simple, rapid, and sensitive DNA assay procedure

1980 • 5,006 citations

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

1997 • 4,867 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease

1995 • 885 citations

Chemopreventive Agent Resveratrol, a Natural Product Derived From Grapes, Triggers CD95 Signaling-Dependent Apoptosis in Human Tumor Cells

1998 • 613 citations

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: A comparison with tyrosine kinase and protein kinase C inhibition

1997 • 532 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

Effect of antioxidants, resveratrol, quercetin, andN-acetylcysteine, on the functions of cultured rat hepatic stellate cells and kupffer cells

1998 • 406 citations

Resveratrol, a remarkable inhibitor of ribonucleotide reductase

1998 • 387 citations

Book Review Ethical Problems in Dialysis and Transplantation (Developments in Nephrology. Vol. 33.) Edited by Carl M. Kjellstrand and John B. Dossetor. 235 pp., illustrated. Boston, Kluwer Academic, 1992. $108.50. 0-7923-1625-8

1993 • 329 citations

Suppression of extracellular signals and cell proliferation through EGF receptor binding by (−)-epigallocatechin gallate in human A431 epidermoid carcinoma cells

1997 • 293 citations

Antiproliferative effect of synthetic resveratrol on human breast epithelial cells.

1998 • 277 citations

Resveratrol increases nitric oxide synthase, induces accumulation of p53 and p21(WAF1/CIP1), and suppresses cultured bovine pulmonary artery endothelial cell proliferation by perturbing progression through S and G2.

1999 • 267 citations

Kinase Inhibitors from Polygonum cuspidatum

1993 • 228 citations

Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells

1997 • 202 citations

Interferon alfa and gamma inhibit proliferation and collagen synthesis of human ito cells in culture

1995 • 181 citations

Cellular localization of type I III and IV procollagen gene transcripts in normal and fibrotic human liver.

1990 • 173 citations

Fine structural analysis of the human pro-alpha 1 (I) collagen gene. Promoter structure, AluI repeats, and polymorphic transcripts.

1985 • 162 citations

Isolation, Identification, and Antioxidant Activity of Three Stilbene Glucosides Newly Extracted from Vitis vinifera Cell Cultures

1998 • 154 citations

Plasma, urine and tissue levels of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after short-term or prolonged administration of red wine to rats.

1996 • 152 citations

Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: Evidence for a role of hepatocyte growth factor

1997 • 150 citations

Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat.

1997 • 149 citations

Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: Evidence for a role of hepatocyte growth factor

1997 • 147 citations

Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor.

1993 • 127 citations

Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study

1999 • 113 citations

Mitogenic effect of transforming growth factor-β1 on human ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor

1993 • 94 citations

α-Smooth muscle actin-positive perisinusoidal stromal cells in human hepatocellular carcinoma

1994 • 93 citations

Determination of trans-Resveratrol in Plasma by HPLC

1999 • 91 citations

The Accumulation of Stilbene Glycosides inVitisviniferaCell Suspension Cultures

1996 • 77 citations

Alpha-smooth muscle actin-positive stromal cells in cholangiocarcinomas, hepatocellular carcinomas and metastatic liver carcinomas

1996 • 71 citations

Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells

1997 • 70 citations

Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase

1999 • 67 citations

Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver

1995 • 55 citations

Inhibition of Eukaryote Serine/Threonine-Specific Protein Kinases by Piceatannol

1998 • 47 citations