Back to search

Equilibrium between Metarhodopsin-I and Metarhodopsin-II Is Dependent on the Conformation of the Third Cytoplasmic Loop

Data up to Jan 2025

Published2005
Citations14
References76

Total Citations Per Year

Abstract

References (76)

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

<scp>CHARMM</scp>: A program for macromolecular energy, minimization, and dynamics calculations

1983 • 14,615 citations

All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins

1998 • 13,827 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

2000 • 5,539 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Searching for Peptide Ligands with an Epitope Library

1990 • 2,080 citations

Intrinsic Disorder and Protein Function

2002 • 1,689 citations

IMMUNOBIOLOGY : the immunesystem in health and disease

2001 • 1,685 citations

Intrinsic Disorder in Cell-signaling and Cancer-associated Proteins

2002 • 1,174 citations

The Retinal Conformation and its Environment in Rhodopsin in Light of a New 2.2 Å Crystal Structure

2004 • 1,025 citations

Phage Display : A Laboratory Manual

2001 • 959 citations

The 2.2 Å crystal structure of transducin-α complexed with GTPγS

1993 • 788 citations

Macromolecular Crystallography Part A

1997 • 779 citations

Structure of Bovine Rhodopsin in a Trigonal Crystal Form

2004 • 718 citations

Standard conformations for the canonical structures of immunoglobulins 1 1Edited by I. A. Wilson

1997 • 687 citations

Functional role of internal water molecules in rhodopsin revealed by x-ray crystallography

2002 • 662 citations

Generalized born model with a simple smoothing function

2003 • 660 citations

Structural determinants for activation of the α-subunit of a heterotrimeric G protein

1994 • 636 citations

Constitutive activity of G-protein-coupled receptors: cause of disease and common property of wild-type receptors

2002 • 606 citations

Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs),

2001 • 598 citations

G-Protein-coupled receptor oligomerization and its potential for drug discovery

2002 • 584 citations

GTPase mechanism of Gproteins from the 1.7-Å crystal structure of transducin α - GDP AIF−4

1994 • 564 citations

Epitopes on protein antigens: Misconceptions and realities

1990 • 532 citations

Site of G Protein Binding to Rhodopsin Mapped with Synthetic Peptides from the α Subunit

1988 • 491 citations

Activation of rhodopsin: new insights from structural and biochemical studies

2001 • 406 citations

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 Å resolution; enzyme–NADP interactions at 2.8 Å resolution

1994 • 358 citations

Rhodopsin structure, dynamics, and activation: A perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking

2003 • 354 citations

Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.

1992 • 307 citations

Electron crystallography reveals the structure of metarhodopsin I

2004 • 297 citations

Structural Features and Light-Dependent Changes in the Cytoplasmic Interhelical E−F Loop Region of Rhodopsin: A Site-Directed Spin-Labeling Study

1996 • 259 citations

Interactions between photoexcited rhodopsin and GTP-binding protein: kinetic and stoichiometric analyses from light-scattering changes.

1981 • 247 citations

Analysis of the Antigen Combining Site: Correlations Between Length and Sequence Composition of the Hypervariable Loops and the Nature of the Antigen

2002 • 243 citations

SURVEY AND SUMMARY: The morph server: a standardized system for analyzing and visualizing macromolecular motions in a database framework

2000 • 241 citations

Rhodopsin: Insights from Recent Structural Studies

2002 • 240 citations

A reinvestigation of the fatty acid content of bovine, rat and frog retinal rod outer segments

1979 • 232 citations

Anti-rhodopsin monoclonal antibodies of defined specificity: Characterization and application

1991 • 229 citations

The G protein‐coupled receptor rhodopsin in the native membrane

2004 • 224 citations

Monomeric G-Protein-Coupled Receptor as a Functional Unit

2005 • 211 citations

Millisecond activation of transducin in the cyclic nucleotide cascade of vision

1984 • 211 citations

NMR structure of a receptor-bound G-protein peptide

1993 • 202 citations

MolMovDB: analysis and visualization of conformational change and structural flexibility

2003 • 187 citations

A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface

2004 • 171 citations

X-Ray Crystallography of Antibodies

1996 • 169 citations

Maximal Rate and Nucleotide Dependence of Rhodopsin-catalyzed Transducin Activation

2001 • 163 citations

Mutation of the Fourth Cytoplasmic Loop of Rhodopsin Affects Binding of Transducin and Peptides Derived from the Carboxyl-terminal Sequences of Transducin α and γ Subunits

2000 • 159 citations

A farnesylated domain in the G protein gamma subunit is a specific determinant of receptor coupling.

1994 • 158 citations

Potent Peptide Analogues of a G Protein Receptor-binding Region Obtained with a Combinatorial Library

1996 • 152 citations

Hetero-oligomerization between β2- and β3-Adrenergic Receptors Generates a β-Adrenergic Signaling Unit with Distinct Functional Properties

2004 • 151 citations

Photoactivated Conformational Changes in Rhodopsin: A Time-Resolved Spin Label Study

1993 • 140 citations

Functional Characterization of Rhodopsin Monomers and Dimers in Detergents

2004 • 134 citations

Filamentous Phage Display of Oligopeptide Libraries

1996 • 120 citations

Allosteric behavior in transducin activation mediated by rhodopsin. Initial rate analysis of guanine nucleotide exchange.

1987 • 105 citations

Structure and Orientation of a G Protein Fragment in the Receptor Bound State from Residual Dipolar Couplings

2002 • 98 citations

Structure and Function in Rhodopsin. Single Cysteine Substitution Mutants in the Cytoplasmic Interhelical E−F Loop Region Show Position-Specific Effects in Transducin Activation

1996 • 84 citations

COMO: a program for combined molecular replacement

2001 • 84 citations

Cooperative binding of the retinal rod G-protein, transducin, to light-activated rhodopsin.

1993 • 57 citations

Antibody Imprint of a Membrane Protein Surface

1998 • 54 citations

Photoactivation of rhodopsin and interaction with transducin in detergent micelles

1989 • 51 citations

Transducin interactions with rhodopsin. Evidence for positive cooperative behavior.

1987 • 48 citations

Structural Requirements for the Stabilization of Metarhodopsin II by the C Terminus of the α subunit of Transducin

2001 • 47 citations

A New Method for Mapping Discontinuous Antibody Epitopes to Reveal Structural Features of Proteins

2003 • 44 citations

The Hydrodynamic Properties of Dark- and Light-activated States of n-Dodecyl β-D-Maltoside-solubilized Bovine Rhodopsin Support the Dimeric Structure of Both Conformations

2004 • 41 citations

Three-Dimensional Model for Meta-II Rhodopsin, an Activated G-Protein-Coupled Receptor

2003 • 41 citations

Rhodopsin Determinants for Transducin Activation

2003 • 40 citations

Actin surface structure revealed by antibody imprints: Evaluation of phage‐display analysis of anti‐actin antibodies

1999 • 27 citations

Epitope identification for human neutrophil flavocytochrome b monoclonals 48 and 449

2000 • 26 citations

Temperature and pH Dependence of the Metarhodopsin I−Metarhodopsin II Equilibrium and the Binding of Metarhodopsin II to G Protein in Rod Disk Membranes

1999 • 25 citations

Structural Models of the Photointermediates in the Rhodopsin Photocascade, Lumirhodopsin, Metarhodopsin I, and Metarhodopsin II

2004 • 18 citations

Supplementary Material 1

2013 • 16 citations

Constraints on the conformation of the cytoplasmic face of dark‐adapted and light‐excited rhodopsin inferred from antirhodopsin antibody imprints

2003 • 16 citations

Cited By (0)

Loading...
Equilibrium between Metarhodopsin-I and Metarhodopsin-II Is Dependent on the Conformation… (2005) – Journal of Biological Chemistry | Metascience Observatory Explorer