Development of the vertebral morphogenetic field in the mouse: Interactions between Crossveinless-2 and Twisted Gastrulation

Bone morphogenetic proteins: multifunctional regulators of vertebrate development.

1996 • 1,959 citations

Controlling TGF-beta signaling.

2000 • 1,806 citations

Controlling TGF-β signaling

2000 • 1,522 citations

BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning.

1995 • 1,021 citations

DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN XENOPUS EMBRYOS

2004 • 652 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

Robustness of the BMP morphogen gradient in Drosophila embryonic patterning

2002 • 463 citations

Cleavage of Chordin by Xolloid Metalloprotease Suggests a Role for Proteolytic Processing in the Regulation of Spemann Organizer Activity

1997 • 398 citations

Shaping BMP morphogen gradients in theDrosophilaembryo and pupal wing

2005 • 288 citations

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling

2000 • 278 citations

Mammalian BMP-1/Tolloid-Related Metalloproteinases, Including Novel Family Member Mammalian Tolloid-Like 2, Have Differential Enzymatic Activities and Distributions of Expression Relevant to Patterning and Skeletogenesis

1999 • 264 citations

Wing Vein Patterning in Drosophila and the Analysis of Intercellular Signaling

2007 • 249 citations

Scaling of the BMP activation gradient in Xenopus embryos

2008 • 230 citations

BMP7 Null Mutation in Mice: Developmental Defects in Skeleton, Kidney, and Eye

1997 • 230 citations

BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation

2003 • 214 citations

Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid

1996 • 210 citations

Spatial bistability of Dpp–receptor interactions during Drosophila dorsal–ventral patterning

2005 • 207 citations

BMP signaling is required for septation of the outflow tract of the mammalian heart

2002 • 205 citations

Homologues of Twisted gastrulation are extracellular cofactors in antagonism of BMP signalling

2001 • 187 citations

Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation

2002 • 170 citations

The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome

2003 • 170 citations

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

2008 • 163 citations

Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins in Drosophila

2000 • 163 citations

Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signaling

2001 • 153 citations

Essential pro-Bmp roles of crossveinless 2 in mouse organogenesis

2006 • 116 citations

Crystal Structure Analysis Reveals How the Chordin Family Member Crossveinless 2 Blocks BMP-2 Receptor Binding

2008 • 112 citations

Extracellular modulation of BMP activity in patterning the dorsoventral axis

2006 • 112 citations

The mammalian twisted gastrulation gene functions in foregut and craniofacial development

2004 • 108 citations

von Willebrand Factor Type C Domain-containing Proteins Regulate Bone Morphogenetic Protein Signaling through Different Recognition Mechanisms

2007 • 107 citations

Crossveinless 2 is an essential positive feedback regulator of Bmp signaling during zebrafish gastrulation

2006 • 107 citations

Crossveinless-2 Is a BMP Feedback Inhibitor that Binds Chordin/BMP to Regulate Xenopus Embryonic Patterning

2008 • 100 citations

Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli lacZ in mouse chimeric embryos.

1990 • 97 citations

The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing

2005 • 93 citations

A Novel Chordin-like Protein Inhibitor for Bone Morphogenetic Proteins Expressed Preferentially in Mesenchymal Cell Lineages

2001 • 91 citations

Mammalian Twisted Gastrulation Is Essential for Skeleto-Lymphogenesis

2003 • 84 citations

A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage

2003 • 84 citations

Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone

2005 • 81 citations

Inactivation of mouse Twisted gastrulation reveals its role in promoting Bmp4 activity during forebrain development

2003 • 77 citations

Human Crossveinless-2 is a novel inhibitor of bone morphogenetic proteins

2004 • 73 citations

A vertebrate crossveinless 2 homologue modulates BMP activity and neural crest cell migration

2004 • 60 citations

Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling

2002 • 57 citations

BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish

2007 • 52 citations

Neuralin-1 is a novel Chordin-related molecule expressed in the mouse neural plate

2001 • 51 citations

crossveinless defines a new family of Twisted‐gastrulation‐like modulators of bone morphogenetic protein signalling

2005 • 44 citations

Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade

2004 • 39 citations

Effect of the Short Ear Gene on Number of Ribs and Presacral Vertebrae in the House Mouse

1946 • 26 citations

RETRACTED: Mouse Crossveinless-2 is the vertebrate homolog of a Drosophila extracellular regulator of BMP signaling

2002 • 13 citations