Protein abundance quantification in embryonic stem cells using incomplete metabolic labelling with ¹⁵N amino acids, matrix‐assisted laser desorption/ionisation time‐of‐flight mass spectrometry, and analysis of relative isotopologue abundances of peptides

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics

2002 • 5,545 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

WWW

2002 • 1,269 citations

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

1992 • 1,259 citations

Analysis of Proteins and Proteomes by Mass Spectrometry

2001 • 1,178 citations

Accurate quantitation of protein expression and site-specific phosphorylation

1999 • 1,014 citations

Mass spectrometric identification of proteins from silver-stained polyacrylamide gel: A method for the removal of silver ions to enhance sensitivity

1999 • 896 citations

Improvement of an "In-Gel" Digestion Procedure for the Micropreparation of Internal Protein Fragments for Amino Acid Sequencing

1995 • 755 citations

Mass spectrometry and the age of the proteome

1998 • 724 citations

Quantitation of microgram amounts of protein in two‐dimensional polyacrylamide gel electrophoresis sample buffer

1985 • 489 citations

IUPAC compendium of chemical terminology

2003 • 408 citations

Dynamics of Protein Turnover, a Missing Dimension in Proteomics

2002 • 396 citations

Sample application by in‐gel rehydration improves the resolution of two‐dimensional electrophoresis with immobilized pH gradients in the first dimension

1994 • 367 citations

Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations

1999 • 311 citations

GC‐MS Analysis of Amino Acids Rapidly Provides Rich Information for Isotopomer Balancing

2000 • 231 citations

High-resolution Mass Spectrometry and Accurate Mass Measurements with Emphasis on the Characterization of Peptides and Proteins by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry

1997 • 145 citations

Site-Specific Mass Tagging with Stable Isotopes in Proteins for Accurate and Efficient Protein Identification

2000 • 119 citations

Theoretical considerations in stable isotope dilution mass spectrometry for organic analysis

1976 • 119 citations

Isotopomer Analysis of Citric Acid Cycle and Gluconeogenesis in Rat Liver

1995 • 112 citations

Table of the isotopic composition of the elements as determined by mass spectrometry

1985 • 111 citations

APPLICATIONS OF MASS ISOTOPOMER ANALYSISTO NUTRITION RESEARCH

1997 • 103 citations

A comparison of calculation procedures for isotope dilution determinations using gas chromatography mass spectrometry

1979 • 90 citations

Mass isotopomer pattern and precursor-product relationship

1992 • 88 citations

Measurement of15N enrichment in multiple amino acids and urea in a single analysis by gas chromatography/mass spectrometry

1993 • 82 citations

Stable isotope labelling in vivo as an aid to protein identification in peptide mass fingerprinting

2002 • 56 citations

Determination of the isotope enrichment of one or a mixture of two stable labelled tracers of the same compound using the complete isotopomer distribution of an ion fragment; theory and application toin vivo human tracer studies

1993 • 45 citations

Analysis of relative isotopologue abundances for quantitative profiling of complex protein mixtures labelled with the acrylamide/D₃‐acrylamide alkylation tag system

2003 • 43 citations

Inverse15N-metabolic labeling/mass spectrometry for comparative proteomics and rapid identification of protein markers/targets

2002 • 42 citations

Stable Isotopes and Mass Isotopomer Study of Fatty Acid and Cholesterol Synthesis

1996 • 39 citations

Plasma kinetics of magnesium and calcium stable isotope tracers in a human subject after simultaneous oral ingestion of25Mg and44Ca determined by thermal ionization mass spectrometry

1993 • 15 citations

Determination of epithelial magnesium transport with stable isotopes

2000 • 8 citations

PRESIDENTS MESSAGE

1992 • 7 citations

LETTERS

1992 • 6 citations

Simultaneous Determination of Plasma Enrichments of 1-13C- and15N-Labelled Phenylalanine and Tyrosine

1998 • 5 citations