Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

1997 • 4,870 citations

Proliferation, cell cycle and apoptosis in cancer

2001 • 3,236 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

1997 • 1,568 citations

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1998 • 1,248 citations

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 • 1,068 citations

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

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Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1999 • 828 citations

Heterozygous Germline Mutations in the p53 Homolog p63 Are the Cause of EEC Syndrome

1999 • 697 citations

Expression of the T-box family genes,Tbx1-Tbx5, during early mouse development

1996 • 654 citations

The ARF/p53 pathway

2000 • 647 citations

Cells: a laboratory manual

1998 • 635 citations

P19 ^ARF stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1999 • 543 citations

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

1997 • 536 citations

The INK4A/ARF locus and its two gene products

1999 • 532 citations

twist is a potential oncogene that inhibits apoptosis

1999 • 511 citations

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1993 • 402 citations

p63 Gene Mutations in EEC Syndrome, Limb-Mammary Syndrome, and Isolated Split Hand–Split Foot Malformation Suggest a Genotype-Phenotype Correlation

2001 • 368 citations

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers

2000 • 367 citations

Cell cycle exit upon myogenic differentiation

1997 • 323 citations

c-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points

1999 • 319 citations

Split-Hand/Split-Foot Malformation Is Caused by Mutations in the p63 Gene on 3q27

2000 • 290 citations

The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia

2001 • 264 citations

T-box genes: what they do and how they do it

1999 • 241 citations

Evolution of Mouse T-box Genes by Tandem Duplication and Cluster Dispersion

1996 • 189 citations

The Spectrum of Mutations in TBX3: Genotype/Phenotype Relationship in Ulnar-Mammary Syndrome

1999 • 169 citations

TBX-3, the Gene Mutated in Ulnar-Mammary Syndrome, Is a Negative Regulator of p19 and Inhibits Senescence

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Expression of T-box genes Tbx2–Tbx5 during chick organogenesis

1998 • 147 citations

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

1999 • 121 citations

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

2001 • 107 citations

Abrogation of Retinoblastoma Protein Function by c-Abl through Tyrosine Kinase-Dependent and -Independent Mechanisms

1995 • 80 citations

Morphological transformation, focus formation, and anchorage independence induced in diploid human fibroblasts by expression of a transfected H-ras oncogene.

1987 • 55 citations

Ulnar-mammary syndrome.

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