Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1990 • 1,882 citations

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

1990 • 1,300 citations

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

1997 • 1,066 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Rb Interacts with Histone Deacetylase to Repress Transcription

1998 • 965 citations

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

1991 • 944 citations

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

1997 • 909 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene

1994 • 628 citations

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

1990 • 577 citations

The T-locus of the mouse

1975 • 567 citations

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

1997 • 536 citations

Induction of muscle pioneers and floor plate is distinguished by the zebrafish no tail mutation

1993 • 502 citations

Mechanism of active transcriptional repression by the retinoblastoma protein

1995 • 494 citations

Transcriptional Repression Mediated by the WT1 Wilms Tumor Gene Product

1991 • 492 citations

The Role of Maternal VegT in Establishing the Primary Germ Layers in Xenopus Embryos

1998 • 477 citations

WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour

1991 • 471 citations

T-Brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex

1995 • 415 citations

Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6

1998 • 408 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 406 citations

The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity

1985 • 387 citations

Isolation, structure, and expression of even-skipped: A second pair-rule gene of Drosophila containing a homeo box

1986 • 380 citations

Different activation domains stimulate transcription from remote (‘enhancer’) and proximal (‘promoter’) positions.

1992 • 359 citations

NAB2, a Corepressor of NGFI-A (Egr-1) and Krox20, Is Induced by Proliferative and Differentiative Stimuli

1996 • 353 citations

Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryos

1991 • 350 citations

eFGF regulates Xbra expression during Xenopus gastrulation.

1994 • 340 citations

Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes

1998 • 333 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning

1996 • 309 citations

The Brachyury gene encodes a novel DNA binding protein.

1993 • 308 citations

The T-box gene family

1998 • 307 citations

Development of the short‐tailed mutant in the house mouse

1935 • 305 citations

The T protein encoded by Brachyury is a tissue-specific transcription factor.

1995 • 287 citations

Functional domains of the Drosophila Engrailed protein.

1993 • 280 citations

Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm

1996 • 280 citations

Evidence of a role for T-☐ genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity

1996 • 271 citations

A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate

1997 • 270 citations

Tbx6,a Mouse T-Box Gene Implicated in Paraxial Mesoderm Formation at Gastrulation

1996 • 256 citations

Active repression of transcription by the engrailed homeodomain protein.

1991 • 248 citations

Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain.

1993 • 241 citations

Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation

1996 • 241 citations

The price of repression

1995 • 232 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

An ancient family of embryonically expressed mouse genes sharing a conserved protein motif with the T locus

1994 • 225 citations

Tbx5 is essential for heart development

1999 • 219 citations

The T genes in embryogenesis

1994 • 215 citations

GAL4 fusion vectors for expression in yeast or mammalian cells

1992 • 213 citations

The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation

1995 • 212 citations

Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta.

1994 • 206 citations

Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless

1996 • 206 citations

Expression cloning of a Xenopus T-related gene (Xombi) involved in mesodermal patterning and blastopore lip formation

1996 • 206 citations

The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation

1996 • 203 citations

A vegetally localized T-box transcription factor in Xenopus eggs specifies mesoderm and endoderm and is essential for embryonic mesoderm formation

1997 • 197 citations

Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped

1988 • 194 citations

Evolution of Mouse T-box Genes by Tandem Duplication and Cluster Dispersion

1996 • 189 citations

Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications

1995 • 183 citations

Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development

1998 • 179 citations

Differential regulation of T-box and homeobox transcription factors suggests roles in controlling chick limb-type identity

1998 • 177 citations

Brachyury-Related Transcription Factor Tbx2 and Repression of the Melanocyte-Specific TRP-1 Promoter

1998 • 171 citations

The Chick Brachyury Gene: Developmental Expression Pattern and Response to Axial Induction by Localized Activin

1995 • 166 citations

Isolation and Characterization of a Gene from the DiGeorge Chromosomal Region Homologous to the MouseTbx1Gene

1997 • 163 citations

An Ascidian Homolog of the Mouse Brachyury (T) Gene is Expressed Exclusively in Notochord Cells at the Fate Restricted Stage

1994 • 160 citations

Nonclassical binding of formylated peptide in crystal structure of the MHC class lb molecule H2-M3

1995 • 155 citations

Tbx genes and limb identity in chick embryo development

1998 • 155 citations

Correlation of wing-leg identity in ectopic FGF-induced chimeric limbs with the differential expression of chick Tbx5 and Tbx4

1998 • 119 citations

Chimeric analysis of T (Brachyury) gene function

1993 • 118 citations

Rescue of the tail defect of Brachyury mice.

1993 • 118 citations

Two novel chick T-box genes related to mouse Brachyury are expressed in different, non-overlapping mesodermal domains during gastrulation

1997 • 117 citations

tbx6,aBrachyury-Related Gene Expressed by Ventral Mesendodermal Precursors in the Zebrafish Embryo

1997 • 110 citations

Cell Anchorage Regulates Apoptosis through the Retinoblastoma Tumor Suppressor/E2F Pathway

1997 • 108 citations

A homology domain shared between Drosophila optomotor-blind and mouse Brachyury is involved in DNA binding

1992 • 101 citations

Genetical studies on the skeleton of the mouse. XXIII. The development of brachyury and anury.

1958 • 100 citations

Domains A and B in the Rb Pocket Interact To Form a Transcriptional Repressor Motif

1996 • 98 citations

Chapter 8 The T-Locus of the Mouse: Implications for Mechanisms of Development

1970 • 98 citations

The lethal(1)optomotor-blind gene of Drosophila melanogaster is a major organizer of optic lobe development: isolation and characterization of the gene.

1992 • 90 citations

Behind the Official Optimism, Flawed Projections

1996 • 89 citations

A novel family of T-box genes in urodele amphibian limb development and regeneration: candidate genes involved in vertebrate forelimb/hindlimb patterning

1997 • 86 citations

Control of cell fate and polarity in the adult abdominal segments of Drosophila by optomotor-blind

1997 • 78 citations

Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins

1990 • 78 citations

Cloning and Mapping of a Human Gene (TBX2) Sharing a Highly Conserved Protein Motif with the Drosophila omb Gene

1995 • 76 citations

Functional differences between mammalian transcription activation domains at the yeast GAL1 promoter.

1994 • 72 citations

A Combined Analysis of Genomic and Primary Protein Structure Defines the Phylogenetic Relationship of New Members of the T-Box Family

1998 • 71 citations

The Rb Family Contains a Conserved Cyclin-Dependent-Kinase-Regulated Transcriptional Repressor Motif

1996 • 67 citations

Characterization of the zebrafish tbx16 gene and evolution of the vertebrate T-box family

1998 • 65 citations

Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans

1995 • 65 citations

Mapping and mutagenesis of the amino-terminal transcriptional repression domain of the Drosophila Krüppel protein.

1994 • 63 citations

Identification, characterization, and localization to Chromosome 17q21-22 of the human TBX2 homolog, member of a conserved developmental gene family

1995 • 51 citations

Newly Identified Paralogous Groups on Mouse Chromosomes 5 and 11 Reveal the Age of a T-Box Cluster Duplication

1997 • 43 citations

Effects of the TWis mutation on notochord formation and mesodermal patterning

1995 • 36 citations

Homozygous inactivation of WTI in a Wilms' tumor associated with the WAGR syndrome

1993 • 32 citations

Two Evolutionarily Conserved Repression Domains in the Drosophila Krüppel Protein Differ in Activator Specificity

1997 • 28 citations

Isolation of a Drosophila T-box gene closely related to human TBX1

1998 • 27 citations

Three novelT-box genes inCaenorhabditis elegans

1997 • 24 citations

TBX10, a member of the Tbx1-subfamily of conserved developmental genes, is located at human Chromosome 11q13 and proximal mouse Chromosome 19

1998 • 17 citations

Mapping and Mutagenesis of the Amino-Terminal Transcriptional Repression Domain of the Drosophila Krüppel Proteint†

1994 • 17 citations

A point mutation within exon 5 of the WT1 gene of a sporadic unilateral Wilms' tumor alters gene function.

1998 • 9 citations