NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

NMR View: A computer program for the visualization and analysis of NMR data

1994 • 3,061 citations

Protein modules and signalling networks

1995 • 2,447 citations

Liddle's syndrome: Heritable human hypertension caused by mutations in the β subunit of the epithelial sodium channel

1994 • 1,238 citations

Empirical correlation between protein backbone conformation and C.alpha. and C.beta. 13C nuclear magnetic resonance chemical shifts

1991 • 1,072 citations

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1993 • 1,026 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1992 • 1,012 citations

Epithelial sodium channel related to proteins involved in neurodegeneration

1993 • 911 citations

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.

1996 • 828 citations

HNCACB, a High-Sensitivity 3D NMR Experiment to Correlate Amide-Proton and Nitrogen Resonances with the Alpha- and Beta-Carbon Resonances in Proteins

1993 • 797 citations

Hypertension caused by a truncated epithelial sodium channel γ subunit: genetic heterogeneity of Liddle syndrome

1995 • 743 citations

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

1997 • 696 citations

Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

1997 • 681 citations

Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics

1996 • 667 citations

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

1994 • 648 citations

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.

1995 • 556 citations

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

1992 • 537 citations

Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide

1996 • 426 citations

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: A quantitative approach

1996 • 418 citations

A familial renal disorder simulating primary aldosteronism but with negligible aldosterone secretion

1963 • 417 citations

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

1995 • 408 citations

The heterotetrameric architecture of the epithelial sodium channel (ENaC)

1998 • 408 citations

Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome.

1996 • 397 citations

The WW domain: a signalling site in dystrophin?

1994 • 380 citations

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity.

1995 • 357 citations

A relational database for sequence-specific protein NMR data

1991 • 357 citations

Enhanced-Sensitivity Triple-Resonance Spectroscopy with Minimal H2O Saturation

1994 • 354 citations

Identification and Characterization of the Dystrophin Anchoring Site on β-Dystroglycan

1995 • 322 citations

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

1995 • 304 citations

The WW Domain of Neural Protein FE65 Interacts with Proline-rich Motifs in Mena, the Mammalian Homolog of DrosophilaEnabled

1997 • 243 citations

An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane.

1994 • 221 citations

FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands

1997 • 208 citations

The C2 Domain of the Ubiquitin Protein Ligase Nedd4 Mediates Ca2+-dependent Plasma Membrane Localization

1997 • 199 citations

Identification of Novel Human WW Domain-containing Proteins by Cloning of Ligand Targets

1997 • 163 citations

Side chain and backbone assignments in isotopically labeled proteins from two heteronuclear triple resonance experiments

1992 • 130 citations

The crystal structure of a mutant protein with altered but improved hydrophobic core packing.

1994 • 110 citations

WWP, a New Amino Acid Motif Present in Single or Multiple Copies in Various Proteins Including Dystrophin and the SH3-Binding Yes-Associated Protein YAP65

1994 • 98 citations

Structure of the N-terminal SH3 domain of GRB2 complexed with a peptide from the guanine nucleotide releasing factor Sos

1994 • 97 citations

Orientation of Peptide Fragments from Sos Proteins Bound to the N-Terminal SH3 Domain of Grb2 Determined by NMR Spectroscopy

1994 • 80 citations

4D NMR triple-resonance experiments for assignment of protein backbone nuclei using shared constant-time evolution periods

1992 • 63 citations

The rsp5-domain is shared by proteins of diverse functions

1995 • 63 citations