Treatment of Chronic Plaque Psoriasis by Selective Targeting of Memory Effector T Lymphocytes

Severe Psoriasis – Oral Therapy with a New Retinoid

1978 • 2,660 citations

An Introduction to Generalized Linear Models.

1991 • 2,659 citations

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1995 • 622 citations

Treatment of Psoriasis

1995 • 517 citations

Inflammatory Skin Diseases, T Cells, and Immune Surveillance

1999 • 474 citations

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.

1990 • 432 citations

Cyclosporine for Plaque-Type Psoriasis

1991 • 427 citations

Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells.

1995 • 248 citations

Predominance of ?memory? T cells (CD4+, CDw29+) over ?naive? T cells (CD4+, CD45R+) in both normal and diseased human skin

1989 • 218 citations

Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses.

1993 • 180 citations

PUVA bath therapy strongly suppresses immunological and epidermal activation in psoriasis: a possible cellular basis for remittive therapy.

1994 • 177 citations

Duration of remission of psoriasis therapies

1999 • 166 citations

T cell activation via CD2 [T, gp50] molecules: accessory cells are required to trigger T cell activation via CD2-D66 plus CD2-9.6/T11(1) epitopes.

1985 • 150 citations

Mechanism of lymphocyte function-associated molecule 3-Ig fusion proteins inhibition of T cell responses. Structure/function analysis in vitro and in human CD2 transgenic mice.

1994 • 126 citations

Proliferating Cells in Psoriatic Dermis Are Comprised Primarily of T Cells, Endothelial Cells, and Factor XIIIa+ Perivascular Dendritic Cells

1991 • 120 citations

The tyrosine kinase activity of p56^lck is increased in human T cells activated via CD2

1991 • 67 citations

SHORT COURSE SINGLE AGENT THERAPY WITH AN LFA-3-IgG1 FUSION PROTEIN PROLONGS PRIMATE CARDIAC ALLOGRAFT SURVIVAL1,2

1996 • 63 citations

Duration of remission during maintenance cyclosporine therapy for psoriasis. Relationship to maintenance dose and degree of improvement during initial therapy

1995 • 20 citations

Intralesional T-Lymphocyte Activation as a Mediator of Psoriatic Epidermal Hyperplasia.

1995 • 20 citations

Analysis of variance and covariance

1990 • 5 citations