Proliferating Cells in Psoriatic Dermis Are Comprised Primarily of T Cells, Endothelial Cells, and Factor XIIIa+ Perivascular Dendritic Cells

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Granulocyte- and granulocyte– macrophage-colony stimulating factors induce human endothelial cells to migrate and proliferate

1989 • 652 citations

Cyclosporine Improves Psoriasis in a Double-blind Study

1986 • 535 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin

1989 • 351 citations

Roles of Adhesion Molecules in T‐Cell Recognition: Fundamental Similarities between Four Integrins on Resting Human T Cells (LFA‐1, VLA‐4, VLA‐5, VLA‐6) in Expression, Binding, and Costimulation

1990 • 322 citations

Abnormal Cell Proliferation in Psoriasis**From the Department of Dermatology, University of Miami School of Medicine, Miami, Florida.

1968 • 293 citations

Epidermal T lymphocytes and HLA-DR expression in psoriasis

2006 • 289 citations

Degranulation of human mast cells induces an endothelial antigen central to leukocyte adhesion.

1989 • 252 citations

Immunocompetent cells in psoriasis

1983 • 241 citations

T-cell subpopulations in the blood and skin of patients with psoriasis

1984 • 227 citations

Predominance of ?memory? T cells (CD4+, CDw29+) over ?naive? T cells (CD4+, CD45R+) in both normal and diseased human skin

1989 • 218 citations

Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis

1982 • 193 citations

Cell Kinetic Basis for Pathophysiology of Psoriasis

1985 • 173 citations

The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis

1987 • 147 citations

IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta.

1990 • 140 citations

Characterization of Mononuclear Cell Infiltrates in Psoriatic Lesions

1978 • 114 citations

Psoriatic Epidermal Cells Demonstrate Increased Numbers and Function of Non-Langerhans Antigen-presenting Cells

1989 • 105 citations

UM4D4+ (CDw60) T Cells Are Compartmentalized into Psoriatic Skin and Release Lymphokines That Induce a Keratinocyte Phenotype Expressed in Psoriatic Lesions

1990 • 95 citations

Involved and uninvolved skin from psoriatic subjects: are they equally diseased? Assessment by skin transplanted to congenitally athymic (nude) mice.

1981 • 94 citations

The role of the 2H4 molecule in the generation of suppressor function in Con A-activated T cells.

1986 • 94 citations

Cutaneous Dermal Ia+ Cells Are Capable of Initiating Delayed Type Hypersensitivity Responses

1990 • 90 citations

Antigen-Presenting Cells in the Induction of Contact Hypersensitivity in Mice: Evidence that Langerhans Cells Are Sufficient but not Required

1989 • 89 citations

Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.

1989 • 78 citations

A Macrophage Phenotype for a Constitutive, Class II Antigen-Expressing, Human Dermal Perivascular Dendritic Cell

1989 • 74 citations

Characterisation of connective tissue cells containing factor XIII subunit a.

1988 • 72 citations

A novel pathway of human T lymphocyte activation. Identification by a monoclonal antibody generated against a rheumatoid synovial T cell line.

1988 • 59 citations

Mechanisms of Cyclosporine A Inhibition of Antigen-Presenting Activity in Uninvolved and Lesional Psoriatic Epidermis

1990 • 59 citations

Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A

1989 • 57 citations

Spreading of Psoriatic Plaques: Alteration of Epidermal Differentiation Precedes Capillary Leakiness and Anomalies in Vascular Morphology

1990 • 53 citations

Adherence of Human Helper/Memory T-Cell Subsets To Psoriatic Dermal Endothelium

1990 • 50 citations

Initial events in psoriasis: quantitative assessment*

2006 • 50 citations

Sequence of changes in psoriatic epidermis. Immunocompetent cell redistribution precedes altered expression of keratinocyte differentiation markers.

1988 • 41 citations

A prospective study of the Koebner reaction and T lymphocytes in uninvolved psoriatic skin.

1988 • 32 citations

Functional characterization of the CD45R (2H4) molecule on CD8 (T8) cells in the autologous mixed lymphocyte reaction system

1989 • 32 citations

Psoriasis: Leukocytes and Cytokines

1990 • 27 citations

3H-thymidine labelling of epidermis and dermal infiltrate in psoriatic erythroderma

1975 • 13 citations